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Displaying drugs 101 - 125 of 11641 in total
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Iduronate 2-sulfatase …
Matched Description: … Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. ... Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues …
Matched Products: … ELAPRASE 2 MG/ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Approved
Investigational
Matched Synonyms: … 2-Phenyl-1,3-indandione ... 2-phenyl-1,3-diketohydrindene ... 2-phenyl-1,3(2H)-Indenedione …
Matched Iupac: … 2-phenyl-2,3-dihydro-1H-indene-1,3-dione …
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- ... (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Synonyms: … (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide ... 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine ... N-(2-(1-(3-(isopropylamino)pyridin-2-yl)piperazine-4-carbonyl)-1H-indol-5-yl)methanesulfonamide …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Synonyms: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Mixtures name: … Levocetirizine Dihydrochloride 2% / Mupirocin 2% / Triamcinolone Acetonide 0.025% ... Hydrocortisone 2.5% / Levocetirizine Dihydrochloride 2% ... Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Used in treatment of iron deficiency anemia.
Approved
Matched Synonyms: … Iron(2+) fumarate …
Matched Iupac: … lambda2-iron(2+) (2E)-but-2-enedioate …
Matched Mixtures name: … Stom #2 ... Super Daily No 2 ... VemaVite-PRx 2 with Fish-Based DHA …
Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak...
Approved
Matched Synonyms: … 2-phenyl-1,3-propanediol dicarbamate ... carbamic acid 2-phenyltrimethylene ester ... Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester …
Matched Iupac: … 3-(carbamoyloxy)-2-phenylpropyl carbamate …
Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Synonyms: … (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2- ... 2-pyridinecarbonitrile, 5-(((1s)-1-(6-chloro-1,2-dihydro-2-oxo-3-quinolinyl)ethyl)amino)-1,6-dihydro- ... 5-(((1s)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2
Matched Description: … hydroxyglutarate (2-HG), a metabolite that participates in tumerogenesis. ... cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an increase in 2- …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring …
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … 2-ene-2-carboxylic acid ... (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct- …
Matched Iupac: … oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Synonyms: … 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide ... 5-acetamido-1,3,4-thiadiazole-2-sulfonamide ... 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Salts cas: … 130693-82-2
Matched Mixtures name: … ARUDOR % 2 + % 0.5 GOZ DAMLASI, 5 ML ... OFTOMIX %2 + %0.5 GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML …
Matched Products: … TRUVEX EYE DROPS 2% W/V ... Dorzolamide Hydrochloride Ophthalmic Solution 2%, 10mL Ophthalmic Solution 2%, 10mL ... Truvex 2% w/v Eye Drops …
A histamine H2 agonist used clinically to test gastric secretory function.
Approved
Matched Synonyms: … 3-(2-aminoethyl)pyrazole ... 2-(3-pyrazolyl)ethylamine ... 2-(1H-pyrazol-5-yl)ethanamine …
Matched Iupac: … 2-(1H-pyrazol-5-yl)ethan-1-amine …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … 2-methoxyphenol ... 2-methoxyl-4-vinylphenol ... 1-hydroxy-2-methoxybenzene …
Matched Iupac: … 2-methoxyphenol …
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Synonyms: … Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside …
Matched Iupac: … (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]- ... 1-methyl-4-propylpyrrolidine-2-carboxamide …
Matched Salts cas: … 24729-96-2
Matched Mixtures name: … LINDAZOL-2 ® ... LINDAZOL-2 ® ... LINDAZOL-2 PLUSS …
Matched Products: … Clinacin 75 mg Tablets For Dogs ... Dalacin C 75 mg/5 ml - Granulat für orale Lösung ... CLINDAMICINA 2% …
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Matched Synonyms: … (E)-5-(2-Bromovinyl)-deoxyuridine …
Matched Iupac: … 5-[(1E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Products: … FUROSEMIDA 20 MG/ 2 ML ... Lasix 20 mg/2 ml Ampullen ... DIRINE INJECTION 20 mg/2 ml …
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxypropanoic acid ... 2-Hydroxypropionic acid ... (±)-2-hydroxypropanoic acid …
Matched Iupac: … 2-hydroxypropanoic acid …
Matched Mixtures name: … Dextrose and Electrolyte No. 75 ... EXTRANEAL PERITONEAL DIALYSIS SOLUTION 75 g/l ... CAPD/DPCA 2
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino ... }-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia ... -1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Synonyms: … L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester ... L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine …
Matched Iupac: … 2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate …
Matched Description: … is an antiviral drug that has been used to manage and treat various herpes infections for more than 2
Matched Salts cas: … 521915-75-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Synonyms: … (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime) …
Matched Iupac: … -hexamethyl-10-(2,4,7-trioxa-1-azaoctan-1-ylidene)-1-oxacyclotetradecan-2-one ... (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy ... }-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13 …
Matched Products: … CLARIPIDINA POLVO PARA SUSPENSION 75 MG/5ML …
Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … 2',3',5'-Triacetyluridine ... 2',3',5'-tri-O-acetyluridine ... Uridine 2',3',5'-triacetate …
Matched Iupac: … [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl acetate …
Matched Description: … It reduces toxicity and cell-death associated with two cytotoxic intermediates: 5-fluoro-2'-deoxyuridine …
Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which...
Approved
Matched Products: … PRALUENT 75 MG/ML SC ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM,2 ADET ... PRALUENT 75 MG/ML SC ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR ENJEKTÖR,2 ADET ... PRALUENT 150 MG/ML SC ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR KALEM,2 ADET …
2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-Benzothiazolyl disulfide ... 2-Mercaptobenzothiazole disulfide ... Bis(2-benzothiazyl) disulfide …
Matched Iupac: … 2-(1,3-benzothiazol-2-yldisulfanyl)-1,3-benzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Synonyms: … (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine- ... (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine- ... 1-Piperazinecarobxylic acid,4-methyl-,(5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4- …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Products: … ZOPLIMAX ® 2 ... ZOMILAN® 2 MG ... ESZOPICLONA 2 MG …
Displaying drugs 101 - 125 of 11641 in total