Displaying drugs 101 - 125 of 11315 in total
Iodide I-131
Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … It is also indicated for use in performance of the radioactive iodide (RAI) uptake test to evaluate thyroid ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its ... For this reason, less toxic iodine isotopes such as I-123 are more frequently used in nuclear imaging …
Ranibizumab
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … only biosimilar drug of ranibizumab available in Canada. ... discovered to inhibit neovascularization and used in the off-label treatment of neovascular age-related ... BYOOVIZ, a biosimilar of LUCENTIS, was approved by Health Canada in March 2022, making it the first and …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml …
Matched Products: … LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml …
Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis ... [A18561,A18562,A18563,A18564,A174934]
Insulin is an essential treatment in the management of Type ... [A18561,A18562,A18563,A18564,A174934] Insulin is also used in the treatment of Type 2 Diabetes (T2D), …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 200 U/ML …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 200 U/ML …
Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Mixtures name: … Theophylline in Dextrose ... Theophylline in Dextrose ... Theophylline 0.8mg/ml In 5% Dextrose Inj …
Matched Categories: … combinations of xanthines …
Matched Products: … Theophylline in Dextrose …
Matched Categories: … combinations of xanthines …
Matched Products: … Theophylline in Dextrose …
Ganirelix
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction ... program was reported in 1998. ... Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. …
Matched Products: … Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze ... Ganirelix Theramex 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze …
Matched Products: … Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze ... Ganirelix Theramex 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of …
Matched Salts cas: … 118120-51-7 …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Description: … synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of …
Matched Salts cas: … 118120-51-7 …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Chenodeoxycholic acid
Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Description: … in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. ... Chenodeoxycholic acid is a bile acid naturally found in the body. ... Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] ... teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic ... [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Matched Salts cas: … 99294-94-7 …
Matched Products: … SONDELBAY (Teriparatide) 20 micrograms/ 80 microliters solution for injection in pre-filled pen ... Teriparatid ratiopharm 20 Mikrogramm/80 Mikroliter Injektionslösung in einem vorgefüllten Injektor …
Matched Salts cas: … 99294-94-7 …
Matched Products: … SONDELBAY (Teriparatide) 20 micrograms/ 80 microliters solution for injection in pre-filled pen ... Teriparatid ratiopharm 20 Mikrogramm/80 Mikroliter Injektionslösung in einem vorgefüllten Injektor …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Description: … It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate ... Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). ... Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). …
Matched Products: … Vaprisol Dextrose In Plastic Container …
Matched Products: … Vaprisol Dextrose In Plastic Container …
Flotufolastat F-18
Flotufolastat F-18 (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane antigen (PSMA).[A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of 18F-labeled ligands for positron emission tomography (PET) offers accurate diagnostic imaging. Unlike 68Ga-labeled PSMA-targeting ligands, 18F-labeled compounds targeting this protein have a longer...
Approved
Investigational
Matched Description: … Flotufolastat F-18 is a diastereoisomer of 18F-rhPSMA-7, and compared to the other diastereoisomers ... a high level of accumulation in tumors. ... [A259846]
In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions …
Ivabradine
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Synonyms: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate ≥70 beats ... Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart ... node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the …
Matched Salts cas: … 1086026-42-7 …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate ≥70 beats ... Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart ... node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the …
Matched Salts cas: … 1086026-42-7 …
Synthetic camphor
Approved
Experimental
Matched Mixtures name: … Re-Lieved 3 in 1 Patch ... 24/7 Life Medicated Chest Rub …
Lipegfilgrastim
Lipegfilgrastim, previously known as XM22, is a pegylated, recombinant granulocyte colony-stimulating factor (G-CSF) that was synthetized using a highly site-specific glycoPEGylation technology . It is used as an alternate to DB00019 for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia. Since July 2013, lipegfilgrastim...
Approved
Investigational
Matched Description: … It aims to reduce the duration of neutropenia and the incidence of febrile neutropenia. ... It is used as an alternate to [DB00019] for prophylactic use in cancer patients receiving chemotherapy ... and less frequent dosing-schedule in addition to acceptable safety and efficacy profile [A32665]. …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …
Matched Products: … LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML …
Sodium ferric gluconate complex
Sodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography. It is composed of iron (III) oxide hydrate directly bonded to sucrose...
Approved
Matched Description: … in a molar ratio of two iron molecules to one gluconate. ... It is used in adult and in pediatric patients over the age of 6 years with chronic kidney disease (CKD ... Sodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia …
Matched Products: … Sodium Ferric Gluconate Complex in Sucrose …
Matched Products: … Sodium Ferric Gluconate Complex in Sucrose …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo ... (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5 ... (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1- …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5 …
Matched Description: … In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5 …
Matched Description: … In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Mavorixafor
Mavorixafor is a CXC chemokine receptor 4 (CXCR4) antagonist. It was first approved by the FDA on April 30, 2024, for the treatment of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a genetic immunodeficiency disorder characterized by a reduced number of mature neutrophils and lymphocytes. WHIM syndrome is caused by...
Approved
Investigational
Matched Description: … [L50647] WHIM syndrome is caused by mutations in the _CXCR4_ gene, which leads to overactivation of CXCR4 ... [A263652] Mavorixafor prevents the activation of CXCR4. ... B-cell non-Hodgkin lymphoma, and solid tumours, including melanoma, mavorixafor is being investigated in …
Magnesium sulfate
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It causes direct inhibition of action potentials in myometrial muscle cells. ... treatment of pre-eclampsia and eclampsia. ... A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the …
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) …
Matched Products: … Magnesium Sulfate in Water ... Magnesium Sulfate in Dextrose ... Magnesium Sulfate In Dextrose …
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) …
Matched Products: … Magnesium Sulfate in Water ... Magnesium Sulfate in Dextrose ... Magnesium Sulfate In Dextrose …
Dopamine
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … One of the catecholamine neurotransmitters in the brain. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating ... A family of receptors (receptors, dopamine) mediate its action. …
Matched Salts cas: … 62-31-7 …
Matched Mixtures name: … Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Dopamine Hci In 5% Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Salts cas: … 62-31-7 …
Matched Mixtures name: … Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose ... Dopamine Hydrochloride in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Dopamine Hci In 5% Dextrose ... Dopamine Hydrochloride in Dextrose …
Dihydroergotamine
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile.
Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6] …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 …
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... Recent improvements have been made in the design of intranasal delivery devices allowing for greater ... A 9,10alpha-dihydro derivative of [ergotamine]. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 …
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... Recent improvements have been made in the design of intranasal delivery devices allowing for greater ... A 9,10alpha-dihydro derivative of [ergotamine]. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Capmatinib
Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and tissue repair. Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known to occur in many...
Approved
Investigational
Matched Iupac: … 2-fluoro-N-methyl-4-{7-[(quinolin-6-yl)methyl]imidazo[1,2-b][1,2,4]triazin-2-yl}benzamide …
Matched Description: … exon 14 skipping. ... [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC. ... of _MET_ amplification in epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)-naive …
Matched Description: … exon 14 skipping. ... [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC. ... of _MET_ amplification in epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)-naive …
Aluminum zirconium octachlorohydrex gly
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … Currently, the FDA allows the inclusion of this substance in concentrations of up to 20% in antiperspirants ... Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of ... The anhydrous form of the compound also has water-absorbing properties. …
Matched Products: … Old Spice Palm Trees In A Box Fiji ... Speed Stick 24/7 Gametime ... Old Spice Arrrrrrg In A Box Krakengard …
Matched Products: … Old Spice Palm Trees In A Box Fiji ... Speed Stick 24/7 Gametime ... Old Spice Arrrrrrg In A Box Krakengard …
Calcium gluconate
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection,...
Approved
Vet approved
Matched Description: … Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium ... Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate …
Matched Products: … Calcium Gluconate in Sodium Chloride ... 2% Calcium Gluconate In Sodium Chloride Injection …
Matched Products: … Calcium Gluconate in Sodium Chloride ... 2% Calcium Gluconate In Sodium Chloride Injection …
Sea salt
Sea salt is the salt obtained from the evaporation of seawater or water from saltwater lakes. Sea salt production is subject to little processing which leaves certain trace minerals and elements behind. In comparison, table salt is mined from underground sedimentary deposits and is more heavily processed to eliminate minerals....
Approved
Matched Description: … In comparison, table salt is mined from underground sedimentary deposits and is more heavily processed ... Sea salt is the salt obtained from the evaporation of seawater or water from saltwater lakes. ... Unlike sea salt, table salt usually contains an additive to prevent clumping and involves addition of …
Matched Products: … S Panax All In One Liquidsoap …
Matched Products: … S Panax All In One Liquidsoap …
Testosterone propionate
Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. Currently, this drug has been discontinued...
Approved
Investigational
Vet approved
Withdrawn
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Description: … It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of ... Currently, this drug has been discontinued in humans, but the vet application is still available as an …
Matched Products: … Malogen In Oil Liq 100mg/ml …
Matched Description: … It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of ... Currently, this drug has been discontinued in humans, but the vet application is still available as an …
Matched Products: … Malogen In Oil Liq 100mg/ml …
Xenon-133
Xenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess pulmonary function.
Approved
Matched Description: … Xenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess …
Displaying drugs 101 - 125 of 11315 in total