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Displaying drugs 101 - 125 of 14962 in total
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. FDA approved on...
Approved
Investigational
Nutraceutical
Matched Synonyms: … ethyl-eicosapentaenoic acid ... Timnodonic acid ethyl ester ... Eicosapentaenoic acid ethyl ester …
Matched Description: … acid (EPA). ... It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce ... Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... -thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis). ... Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Salts name: … Cefotaxime sodium
Matched Products: … Cefotaxime and Dextrose ... CEFOTAXIME SODIUM ... Cefotaxime Sodium Sterile …
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Synonyms: … Podophyllinic acid lactone …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and
Matched Mixtures name: … Cepacol Citrus Extra Strength Lozenges ... Cepacol Sore Throat Maximum Numbing Citrus ... Cepacol Extra Strength Orange Citrus Lozenge …
Matched Categories: … Esters of Aminobenzoic Acid ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Cepacol Sensations Sore Throat Hydra citrus splash ... Sting and Bite ... Bite and Sting relief …
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Potassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. It can be made as the product of potassium hydroxide's absorbent reaction with carbon dioxide. It presents a large capacity to absorb moisture.
Approved
Matched Synonyms: … Carbonic acid, dipotassium salt …
Matched Mixtures name: … Vit C W Calc-mag and Potass Powder ... Buffered Vitamin C Powder With Ca Mg and K …
Matched Categories: … Carbonic Acid
Matched Products: … Moonstar Face and Body Mist …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations ... Drug-Related Side Effects and Adverse Reactions …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid ... 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid
Matched Description: … Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA ... It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and
Matched Categories: … Gabapentin and Prodrugs ... Amino Acids, Peptides, and Proteins …
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … Pseudomonic acid ... Pseudomonic acid A ... ,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
Matched Iupac: … 2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl}oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... chemical structure and mode of action apart from other antibiotic agents. …
Matched Mixtures name: … Pre and Post Sx Pouch …
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Synonyms: … α-butyloxycinchonic acid-γ-diethylethylenediamine ... α-butyloxycinchoninic acid diethylethylenediamide ... 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide …
Matched Description: … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is …
Matched Categories: … Analgesics and Anesthetics ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxybenzoic acid methyl ester …
Matched Description: … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. ... It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic …
Matched Mixtures name: … Advanced Citrus ... Oral Dent Citrus ... Oral Dent Citrus
Matched Products: … Neuro Max Pain and Muscle Relief Gel ... Dermorub Liniment Muscle and Joint ... Flexitol Foot and Knee Pain Relief …
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Synonyms: … Indium (111In) pentetic acid
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and
Matched Categories: … indium (111In) pentetic acid
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Cloxacillin sodium ... Cloxacillin sodium hydrate …
Matched Products: … Cloxacillin Sodium for Injection ... Cloxacillin Sodium Sterile Inj 250mg/vial …
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Categories: … enalapril and nitrendipine ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Synonyms: … Nitric acid, gallium salt, anhydrate …
Matched Description: … [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. ... cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and
Matched Categories: … Calcium-Regulating Hormones and Agents …
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid
Matched Description: … [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid
Lithium has been used to treat manic episodes since the 19th century . Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Approved
Matched Synonyms: … Carbonic acid, dilithium salt …
Matched Description: … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse …
Matched Categories: … Carbonic Acid
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Products: … Dicloxacillin Sodium
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Pteroylmonoglutamic acid hydrolase G2 …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... This can lead to delayed renal clearance of methotrexate and elevated drug plasma levels, increasing …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, ... skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, …
Matched Mixtures name: … Benzocaine and Triclosan ... Benzocaine and Triclosan ... APRIL Bath and Shower Anti-bacterial Hand 3 Pack …
Matched Categories: … Fatty Acid Synthesis Inhibitors ... Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Products: … Citrus and Casaba Antibacterial Hand Wash ... Citrus Basil and Lime Antibacterial Hand Wash ... Sage and Citrus Antibacterial Foaming Hand Wash …
Displaying drugs 101 - 125 of 14962 in total