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Displaying drugs 101 - 125 of 8327 in total

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … in the pathophysiology and treatment of affective disorders, plus discussed the potential value of zinc ... as a marker of these diseases [L2097]. ... A metallic element of atomic number 30 and atomic weight 65.38. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Matched Categories: … combinations of penicillins …

Sarecycline

Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Description: … from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 [A40005]. ... inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients nine years of age and ... of young adults aged 12 to 25 years globally - with the possibility of permanent physical and mental …
Matched Categories: … combinations of tetracyclines …

Temocillin

Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Phthalylsulfathiazole

Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Matched Categories: … combinations of sulfonamides …

Gallium Ga-68 gozetotide

Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Description: … [L43542] In December of the same year, the drug was fully authorized by the EMA. ... [L26981] Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries ... Human Use (CHMP) recommended Ga-68 gozetotide be granted marketing authorization for the diagnosis of …
Matched Categories: … Diagnostic Uses of Chemicals …

Perflutren

Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the...
Approved
Matched Description: … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart ... to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of ... difference in density between the gas-filled bubbles and the blood around them creates an increased level of …
Matched Categories: … Diagnostic Uses of Chemicals …

Tigecycline

Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Description: … It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus …
Matched Categories: … combinations of tetracyclines …

Sibutramine

Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … heart attack and stroke in patients with a history of heart disease. ... usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of ... Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pretomanid

Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Description: … Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality ... forms of this disease, which have shown resistance to standard therapy regimens. ... Research in recent years has been geared toward the development of novel therapies that target persistent …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Corifollitropin alfa

Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … risk of ovarian hyperstimulation in the high responder study group of women [L2276], [A32526]. ... effectiveness of this drug, however, warns at the same time against the possibility of an increased ... In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … time to achieving normal potassium levels in the blood was 2.2 hours, with 92% of patients achieving ... [L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials ... and two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Lithium citrate

Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Carbenicillin

Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Ethionamide

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Description: … It also may be used for treatment of leprosy. ... (From Smith and Reynard, Textbook of Pharmacology, 1992, p868) …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Methoxyphenamine

Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pivmecillinam

Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Matched Categories: … combinations of penicillins …

Hydrocortisone acetate

Approved
Vet approved
Matched Mixtures name: … Cortisporin-TC ... Cortisporin TC ... Cortisporin-TC …

Levomilnacipran

Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Description: … selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of …
Matched Categories: … combinations of tetracyclines …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic ... Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced ... of pyridoxine in the above-mentioned metabolic functions). …
Matched Mixtures name: … Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Chloroprocaine

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … the nerve impulse and reducing the rate of rise of the action potential. ... anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of ... [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration …
Matched Categories: … Esters of Aminobenzoic Acid …

Quinethazone

Quinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Approved
Matched Categories: … combinations of sulfonamides …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … [A263071] Chemically, it consists of 2 heavy and 2 light chains, with each light chain consisting of ... Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear ... factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Displaying drugs 101 - 125 of 8327 in total