Methoxyphenamine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Methoxyphenamine
DrugBank Accession Number
DB13624
Background

Not Available

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 179.2588
Monoisotopic: 179.131014171
Chemical Formula
C11H17NO
Synonyms
  • 2-Methoxymethamphetamine
  • Méthoxyphénamine
  • Methoxyphenamine
  • Methoxyphenaminum
  • Metoxifenamina

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbaloparatideThe risk or severity of adverse effects can be increased when Methoxyphenamine is combined with Abaloparatide.
AcebutololThe therapeutic efficacy of Acebutolol can be decreased when used in combination with Methoxyphenamine.
AceclofenacThe risk or severity of hypertension can be increased when Aceclofenac is combined with Methoxyphenamine.
AcemetacinThe risk or severity of hypertension can be increased when Methoxyphenamine is combined with Acemetacin.
AcetazolamideAcetazolamide may decrease the excretion rate of Methoxyphenamine which could result in a higher serum level.
AcetophenazineAcetophenazine may decrease the stimulatory activities of Methoxyphenamine.
Acetylsalicylic acidThe risk or severity of hypertension can be increased when Acetylsalicylic acid is combined with Methoxyphenamine.
AclidiniumThe risk or severity of Tachycardia can be increased when Aclidinium is combined with Methoxyphenamine.
AcrivastineMethoxyphenamine may decrease the sedative and stimulatory activities of Acrivastine.
AdenosineThe risk or severity of Tachycardia can be increased when Adenosine is combined with Methoxyphenamine.
Interactions
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Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Methoxyphenamine hydrochloride52V8BVV7FX5588-10-3FGSJNNQVSUVTPW-UHFFFAOYSA-N

Categories

ATC Codes
R03CB02 — Methoxyphenamine
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as amphetamines and derivatives. These are organic compounds containing or derived from 1-phenylpropan-2-amine.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Phenethylamines
Direct Parent
Amphetamines and derivatives
Alternative Parents
Phenylpropanes / Phenoxy compounds / Methoxybenzenes / Anisoles / Aralkylamines / Alkyl aryl ethers / Dialkylamines / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
Alkyl aryl ether / Amine / Amphetamine or derivatives / Anisole / Aralkylamine / Aromatic homomonocyclic compound / Ether / Hydrocarbon derivative / Methoxybenzene / Organic nitrogen compound
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
J3Z5SRI26Z
CAS number
93-30-1
InChI Key
OEHAYUOVELTAPG-UHFFFAOYSA-N
InChI
InChI=1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
IUPAC Name
[1-(2-methoxyphenyl)propan-2-yl](methyl)amine
SMILES
CNC(C)CC1=CC=CC=C1OC

References

General References
  1. FDA Thailand Product Information: Asmeton-S (methoxyphenamine/noscapine/aminophylline/chlorpheniramine) oral tablets [Link]
Human Metabolome Database
HMDB0041930
ChemSpider
3974
RxNav
29704
ChEBI
134817
ChEMBL
CHEMBL2010507
Wikipedia
Methoxyphenamine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.783 mg/mLALOGPS
logP2.13ALOGPS
logP2.08ChemAxon
logS-2.4ALOGPS
pKa (Strongest Basic)10.04ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area21.26 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity54.94 m3·mol-1ChemAxon
Polarizability20.79 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on June 23, 2017 20:45 / Updated on February 21, 2021 18:54