Displaying drugs 1251 - 1275 of 8802 in total
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Synonyms: … 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide ... Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)- …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Matched Iupac: … 2-chloro-N-[4-chloro-3-(pyridin-2-yl)phenyl]-4-methanesulfonylbenzamide …
Parachlorophenol
P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Approved
Matched Synonyms: … 4-chlorphenol ... 4-Chlorophenol …
Matched Iupac: … 4-chlorophenol …
Matched Iupac: … 4-chlorophenol …
Fomepizole
Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Synonyms: … 4-methylpyrazol ... 4-methylpyrazole …
Matched Iupac: … 4-methyl-1H-pyrazole …
Matched Iupac: … 4-methyl-1H-pyrazole …
Medicago sativa pollen
Medicago sativa pollen is the pollen of the Medicago sativa plant. Medicago sativa pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET …
Chrysonilia sitophila
Chrysonilia sitophila is a fungus which can provoke allergic reactions. Chrysonilia sitophila extract is used in allergenic testing.
Approved
Orthosiphon aristatus leaf
Approved
Experimental
Thiabendazole
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Synonyms: … 4-(2-benzimidazolyl)thiazole ... 2-(thiazol-4-yl)benzimidazole ... 2-(4-thiazolyl)-1H-benzimidazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole …
Pine tar
Approved
Experimental
Dextroamphetamine
Dextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Approved
Illicit
Matched Synonyms: … (+)-(S)-amphetamine ... (S)-amphetamine ... (S)-(+)-amphetamine …
Cefamandole
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Ambroxol
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Synonyms: … Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)- ... trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol ... trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol …
Matched Iupac: … (1r,4r)-4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol …
Matched Salts cas: … 23828-92-4 …
Matched Products: … AMBROHEXAL S SAFT ... AMBROHEXAL S HUSTEN15MG/ML …
Matched Iupac: … (1r,4r)-4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol …
Matched Salts cas: … 23828-92-4 …
Matched Products: … AMBROHEXAL S SAFT ... AMBROHEXAL S HUSTEN15MG/ML …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Mixtures name: … AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S …
Matched Products: … BRENOXIL-S ... Amox S 250 Sus 250mg/5ml ... Amox S 125 Sus 125mg/5ml …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0 …
Matched Mixtures name: … AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S ... AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S …
Matched Products: … BRENOXIL-S ... Amox S 250 Sus 250mg/5ml ... Amox S 125 Sus 125mg/5ml …
Oxymetazoline
Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Synonyms: … 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline …
Talc
Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes.
Although talc has been widely used...
Approved
Matched Iupac: … tetrasilicon(4+) trimagnesium(2+) dihydroxide decaoxidandiide …
Trilaciclib
Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage small cell lung cancer. CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis...
Approved
Investigational
Matched Iupac: … [7.4.0.0^{2,7}]tridecane]-1'(9'),7',10',12'-tetraen-6'-one ... 12'-{[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}-2',5',11',13'-tetraazaspiro[cyclohexane-1,3'-tricyclo …
Matched Categories: … Cyclin-dependent Kinase 4 Inhibitors …
Matched Categories: … Cyclin-dependent Kinase 4 Inhibitors …
Noxytiolin
Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for burns.
Approved
Matched International brands: … Noxyflex S …
Calfactant
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Iobenguane sulfate I-123
Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Approved
Investigational
Salix lasiolepis pollen
Salix lasiolepis pollen is the pollen of the Salix lasiolepis plant. Salix lasiolepis pollen is mainly used in allergenic testing.
Approved
Pinus sylvestris pollen
Pinus sylvestris pollen is the pollen of the Pinus sylvestris plant. Pinus sylvestris pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 4-pine Mix, Austrian/loblolly/scotch/white Pollen …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Iupac: … disodium 4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)[(1Z,4Z)-4-{ethyl[(3-sulfophenyl)methyl]iminiumyl …
Haemagglutinin-strain B
Approved
Serdexmethylphenidate
Attention Deficit Hyperactivity Disorder (ADHD) is an early-onset neurodevelopmental disorder that often extends into adulthood and is characterized by developmentally inappropriate and impaired attention, impulsivity, and motor hyperactivity.[A230698, A230703] The underlying cause of ADHD is unclear but likely involves dysfunction in dopaminergic and noradrenergic neurotransmission, as evidenced by the clear...
Approved
Displaying drugs 1251 - 1275 of 8802 in total