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Displaying drugs 1351 - 1375 of 8681 in total
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising...
Approved
Investigational
Matched Synonyms: … (±)-trans-2-phenylcyclopropylamine ... trans-2-phenylcyclopropylamine ... trans-DL-2-Phenylcyclopropylamine …
Matched Iupac: … 2-phenylcyclopropan-1-amine …
Matched Description: … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1- …
Matched Salts cas: … 13492-01-8
Hormone receptor (HR) positive, especially estrogen receptor-positive, HER2-negative breast cancer is the most common subtype of metastatic breast cancer, resulting in more than 400,000 deaths annually. Although endocrine-based therapy is the first line of treatment, resistance eventually emerges, leaving chemotherapy the only but often ineffective treatment left. Therefore, significant research...
Approved
Investigational
Matched Iupac: … 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine-4-carboxamide …
Matched Categories: … MATE 2 Inhibitors …
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ATODEL 2 TABLET 2 mg ... ไบเพรส 2 ... กาเพรส 2
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid …
Matched Iupac: … N-benzyl-3-[(pyridin-4-yl)formohydrazido]propanamide …
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as...
Approved
Vet approved
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Synonyms: … Norplant 3-oxime ... D-Norgestrel 3-oxime ... Levonorgestrel 3-oxime …
Matched Iupac: … (1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en …
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one ... 5-aza-2'-deoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system. Agonism of peripheral...
Approved
Investigational
Matched Synonyms: … 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2
Matched Iupac: … 5-{[(2S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]propanamido ... ]methyl}-2-methoxybenzoic acid …
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … (AcelRx), was approved on November 2, 2018 [L4717]. …
Matched Salts cas: … 60561-17-3
Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Synonyms: … Copper(2+) chloride …
Matched Salts cas: … 10125-13-0
Approved
Matched Iupac: … ,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid ... 4-{2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H …
Matched Salts cas: … 125-04-2
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-sulfanilamidopyrimidine ... 2-sulfanilylaminopyrimidine ... N(1)-2-Pyrimidylsulfanilamide …
Matched Iupac: … 4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 547-32-0
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … MATE 2 Substrates …
Matched Products: … DOLPIRID 100 MG/2 ML AMPUL, 6 ADET ... MERESA 100MG / 3 ML ENJEKSİYONLUK ÇÖZLELTİ, 100 ADET ... ZEPRID 100 MG/ 2 ML ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B virus vaccine, B-Massachusetts-2-2012-like virus, recombinant …
Matched Name: … Influenza B virus B/Massachusetts/2/2012 recombinant hemagglutinin antigen …
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … 2-(Cyclohexylaminothio)benzothiazole ... Benzothiazyl-2-cyclohexylsulfenamide ... N-cyclohexyl-2-Benzothiazosulfenamide …
Matched Iupac: … N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Synonyms: … N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine ... 2-methyldiphenhydramine ... 2-(phenyl-o-tolylmethoxy)ethyldimethylamine …
Matched Iupac: … dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine …
Streptococcus pneumoniae type 3 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 3 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … pneumococcal capsular polysaccharide type 3 vaccine …
Matched Name: … Streptococcus pneumoniae type 3 capsular polysaccharide antigen …
Matched Description: … capsular polysaccharides from the invasive pneumococcal type 3 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 3 capsular polysaccharide antigen is a vaccine that contains highly purified …
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 2'-Deoxy-5-fluorouridine ... 5-Fluoro-2-desoxyuridine ... 5-fluoro-2'-deoxyuridine …
Matched Iupac: … 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Approved
Matched Synonyms: … 2-Carbamoylphenol ... 2-Hydroxybenzamide ... 2-Carboxamidophenol …
Matched Iupac: … 2-hydroxybenzamide …
Matched Categories: … Non COX-2 selective NSAIDS …
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is...
Approved
Investigational
Vet approved
Matched Synonyms: … Calcium 2-hydroxypropanoate (1:2) ... 2-Hydroxypropanoic acid calcium salt …
Matched Iupac: … calcium bis(2-hydroxypropanoate) …
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … (+)-5-Iodo-2'-deoxyuridine ... 2'-Deoxy-5-iodouridine ... 5-iodo-2'-deoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Synonyms: … N-(2-Methylphenyl)-2-(propylamino)propanamide ... 2-(Propylamino)-o-propionotoluidide ... o-Methyl-2-propylaminopropionanilide …
Matched Iupac: … N-(2-methylphenyl)-2-(propylamino)propanamide …
Matched Salts cas: … 1786-81-8
Matched Mixtures name: … PRICANEST 3% FELIPRESINACARPULES …
Matched Products: … Takipril hyperbar 2 % Injektionslösung ... PRİLOSEL % 2 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... PRİNEST %2 ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol ... 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol …
Matched Iupac: … 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol …
Displaying drugs 1351 - 1375 of 8681 in total