Displaying drugs 1351 - 1375 of 8310 in total
Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … (2-bromobenzyl)ethyldimethylaminium ... 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium ... N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
PBT-434
Approved
Investigational
Matched Synonyms: … 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-one …
Matched Iupac: … 5,7-dichloro-2-[(ethylamino)methyl]-8-hydroxy-3-methyl-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 5,7-dichloro-2-[(ethylamino)methyl]-8-hydroxy-3-methyl-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Carbidopa
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid …
Matched Iupac: … (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid …
Matched Description: … Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Matched Iupac: … (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid …
Matched Description: … Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Abrocitinib
Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Iupac: … N-[(1s,3s)-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]cyclobutyl]propane-1-sulfonamide …
Tipiracil
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Salts cas: … 183204-72-0 …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Salts cas: … 183204-72-0 …
Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Influenza A virus A/Cambodia/e0826360/2020 IVR-224 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Cephalexin
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Salts cas: … 23325-78-2 ... 105879-42-3 ... 38932-40-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Salts cas: … 23325-78-2 ... 105879-42-3 ... 38932-40-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pemigatinib
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … metastatic cholangiocarcinoma in previously treated adult patients with a fibroblast growth factor receptor 2 ... intrahepatic cholangiocarcinoma exhibited gene rearrangements resulting in oncogenic fibroblast growth factor 2 …
Matched Categories: … Fibroblast Growth Factor 2, antagonists & inhibitors ... Receptor, Fibroblast Growth Factor, Type 2, antagonists & inhibitors …
Matched Categories: … Fibroblast Growth Factor 2, antagonists & inhibitors ... Receptor, Fibroblast Growth Factor, Type 2, antagonists & inhibitors …
Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Influenza A virus A/Indiana/08/2018 (H3N2) antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Calcium carbimide
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Salts cas: … 8000-10-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FILINSEL 24 MG/ML IV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 10 ML X 3 AMPUL …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … FILINSEL 24 MG/ML IV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 10 ML X 3 AMPUL …
2-mercaptobenzothiazole
Approved
Experimental
Vet approved
Matched Synonyms: … 2-MBT ... 2-Benzothiazolethiol ... Benzothiazole-2-thiol …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Zavegepant
Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl ... )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- …
Matched Iupac: … -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide ... N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide ... N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sodium phosphate, dibasic
Approved
Matched Synonyms: … Phosphoric acid, sodium salt (1:2) …
Matched Mixtures name: … Phoxillum B22k4/0 …
Matched Mixtures name: … Phoxillum B22k4/0 …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Description: … By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 …
Mupirocin
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid ... 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] …
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Mixtures name: … Lidocaine 2% / Mupirocin 2% ... Levocetirizine Dihydrochloride 2% / Mupirocin 2% / Triamcinolone Acetonide 0.025% ... Metronidazole 1% / Mupirocin 2% / …
Matched Products: … Mupirocin 2% ... Bactroban 2 % - Creme ... Mupicin ointment 2%w/w …
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Mixtures name: … Lidocaine 2% / Mupirocin 2% ... Levocetirizine Dihydrochloride 2% / Mupirocin 2% / Triamcinolone Acetonide 0.025% ... Metronidazole 1% / Mupirocin 2% / …
Matched Products: … Mupirocin 2% ... Bactroban 2 % - Creme ... Mupicin ointment 2%w/w …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta ... (b)pyrrole-2-carboxylic acid …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … b]pyrrole-2-carboxylic acid ... (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sertraline
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
Several weeks of therapy with sertraline may be required before...
Approved
Matched Salts cas: … 79559-97-0 …
Influenza A virus A/Hong Kong/2671/2019 (H3N2) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Fingolimod
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Iupac: … 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol …
Matched Description: … Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 …
Matched Salts cas: … 162359-56-0 …
Matched Description: … Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 …
Matched Salts cas: … 162359-56-0 …
Phendimetrazine
Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Approved
Illicit
Matched Synonyms: … (2S,3S)-3,4-dimethyl-2-phenylmorpholine …
Matched Iupac: … (2S,3S)-3,4-dimethyl-2-phenylmorpholine …
Matched Iupac: … (2S,3S)-3,4-dimethyl-2-phenylmorpholine …
Povidone K30
A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See povidone for full details.
Approved
Experimental
Matched Synonyms: … 1-vinylpyrrolidin-2-one homopolymer …
Displaying drugs 1351 - 1375 of 8310 in total