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Displaying drugs 1351 - 1375 of 1987 in total

4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol

Experimental
Matched Name: … 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol …
Matched Iupac: … 4-{2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl}phenol …

Metamfetamine

Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse. The...
Approved
Illicit
Withdrawn
Matched Synonyms: … d-1-phenyl-2-methylaminopropane …
Matched Description: … It is a scheduled drug in most countries due to its high potential for addiction and abuse. ... Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine ... Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Azafenidin

Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Investigational
Matched Synonyms: … 2-(2,4-dichloro-5-(2-propynyloxy)phenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one …
Matched Description: … investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and …

Pralatrexate

Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell ... lung cancer, breast cancer, and bladder cancer. ... that is overexpressed in malignant cells and is upregulated by oncogenes. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … SOLUTION FOR INFUSION 20MG/ML ... Folotyn 20mg/ml Solution for Infusion …

Human cytomegalovirus immune globulin

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … antibody for cytomegalovirus (CMV). ... CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and ... vaginal excretions, semen, breast milk and blood [L2228]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …

Pyrophosphoric acid

Approved
Experimental
Matched Products: … TECHNESCAN PYP, KIT FOR RADIOPHARMACEUTICAL PREPARATION, 20MG/VIAL …

Carmustine

A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Carmustine for Injection USP ... BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …

VK-0214

Investigational
Matched Synonyms: … Phosphonic acid, p-((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy)methyl)- …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Iupac: … 2-[({[2,6-bis(propan-2-yl)phenyl]carbamoyl}methyl)(carboxymethyl)amino]acetic acid (99Tc)technetium …
Matched Description: … It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure ... the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary ... Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents ... Hepatic and Reticulo Endothelial System …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …

Methylnaltrexone

Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... as interchain bonds and 23 interchain bonds. ... [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KEYTRUDA SOLUTION FOR INFUSION 25MG/ML ... Keytruda 100mg Solution for Infusion …

Faricimab

Retinal vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) are typically caused by retinal ischemia and subsequent neovascularization (NV).[A225985, A225990, A225995] Vascular endothelial growth factor A (VEGF-A) is a well-known mediator of retinal NV, and many currently approved RVD therapies...
Approved
Investigational
Matched Description: … [L42305] In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended faricimab ... and diabetic macular edema. ... vascular diseases (RVDs) such as diabetic macular edema (DME), age-related macular degeneration (AMD), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … VABYSMO 6mg/0.05mL Solution for Intravitreal Injection …

3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE

Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
Matched Iupac: … (2S,3R)-3-formyl-N,2-dihydroxy-5-methylhexanamide …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …

Dupilumab

Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Agents for Dermatitis, Excluding Corticosteroids …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … forms and those products formulated for preparation of solution prior to ingestion. ... in fertilizers and explosives. ... crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and …
Matched Mixtures name: … Accusol 35 Potassium 4 mmol/l Solution for Haemofiltration, Haemodialysis and Haemodiafiltration ... ELECTRAL FORTE GRANULES ... FORTRANS FOR ORAL SOLUTION …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Potassium Chloride for Oral Solution ... Potassium Chloride for Hemodialysis 7.55 ... Potassium Chloride for Injection Concentrate …

Oxidronic acid

Approved
Matched Products: … TECHNESCAN HDP FOR INJECTION 3 mg/vial ... TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vial …

Ferric carboxymaltose

Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Description: … Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. …
Matched Products: … Ferinject Solution for Injection 50mg/ml ... Ferinject® 50 mg iron/mL solution for injection/infusion …

Sincalide

Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as CCK-8. Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating protein and fat digestion...
Approved
Matched Description: … small bowel for cholesterol analysis, enzymatic activity analysis, and x-ray examination respectively ... protein and fat digestion in the body. ... Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders …
Matched Categories: … Tests for Bile Duct Patency ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Sincalide for Injection …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … There is no specific treatment for hepatitis. ... The hepatitis B virus induces a severe form of viral hepatitis. ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …

Antithrombin III human

A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Anbinex Powder For Injection 500 I.U. ... Anbinex Powder For Injection 1000 I.U. …

Basiliximab

A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … light chain constant region genes and mouse heavy and light chain variable region genes encoding the ... ) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and ... established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMULECT FOR INJECTION 20 mg/vial ... SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL …

4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE

Experimental
Matched Name: … 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE …
Matched Iupac: … 4-phenoxy-N-[(pyridin-2-yl)methyl]benzamide …

3-(4-NITRO-PHENOXY)-PROPAN-1-OL

Experimental
Matched Name: … 3-(4-NITRO-PHENOXY)-PROPAN-1-OL …
Displaying drugs 1351 - 1375 of 1987 in total