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Displaying drugs 1401 - 1425 of 1737 in total

Acalabrutinib

To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others. As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Description: … in adult patients with Mantle cell lymphoma (MCL) who have already received at least one prior therapy ... been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and ... inhibitor indicated for the treatment of chronic lymphocytic leukemia, small lymphocytic lymphoma, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … CALQUENCE® 100MG ... CALQUENCE HARD CAPSULES 100MG ... Calquence Hard Capsules 100mg …

Insulin degludec

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and ... tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. …
Matched Mixtures name: … Xultophy 100/3.6 ... RYZODEG 100 UNIDADES/ML ... Ryzodeg® FlexTouch® 100 U/ml Solution for Injection …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRESIBA® 100 U/ML ... เทรสิบา เฟล็กซ์ทัช 100 ยูนิต/มล. ... Tresiba® FlexTouch® 100 U/ml Solution for Injection …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited …
Matched Products: … PALEXIS® RETARD 100 MG ... Nucynta ER Tablets 100 mg ... NUCYNTA ER Tablets 100mg …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays. ... (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left ... benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Iodinated ... Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media …
Matched Products: … Optiray 350 Prefilled Syringe 100ml ... OPTIRAY 240 STERIL ENJEKTABL COZELTI ICEREN CAM SISE, 100 ML ... OPTIRAY 320 STERIL ENJEKTABL COZELTI ICEREN CAM SISE, 100 ML …

Rebamipide

Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Approved
Investigational
Matched Description: … Gastric Adenoma and Early Gastric Cancer. ... Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … REBA - 100 ... บาปิด 100 ... MUCOSTA TABLETS 100 …

Guselkumab

Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … TREMFYA 100MG/ML SOLUTION FOR INJECTION ... Tremfya One-Press 100mg/ml Solution for Injection ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …

Celecoxib

Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... tramadol and celecoxib ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... amlodipine and celecoxib …
Matched Products: … CELEBIB 100 (CELECOXIB CAPSULES 100MG) ... CELCOX 100 ... Celecoxib 100 mg …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … XOLYXA® 100 MG ... BOSULIF®100 MGTABLETAS RECUBIERTAS. ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Sugammadex

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intubation that patients may require...
Approved
Matched Description: … Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United ... relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and ... Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary …
Matched Salts name: … Sugammadex sodium …
Matched Products: … BRIDION 100MG/ML SOLUTION FOR INJECTION ... Bridion Solution For Injection 100mg/ml ... Sugagelan 100 mg/ml-Injektionslösung …

Acetohydroxamic acid

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Description: … Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure ... Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … CIPROFLOXACINO 100 MG/10 ML INYECTABLE ... CIPROFLOXACINO 100 MG / 10 ML INYECTABLE …

Papaverine

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and ... it may have direct actions on calcium channels. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Papaverine and Derivatives …
Matched Products: … PAPAVERIN HCL BIOFARMA 40 MG / 2ML AMPUL, 100 ADET ... PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 100 ADET ... PAPAVERIN HCL BIOFARMA 60 MG / 2ML AMPUL, 100 ADET …

Botulinum toxin type A

In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic...
Approved
Investigational
Matched Description: … is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other ... [A231824] With a wide variety of applications and favourable safety profile, Botulinum toxin A injection ... [A231819,L32569] A popular use for Botox is the treatment of facial wrinkles and lines, however, there …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … NEURONOX® 100 UI ... XEOMIN®100 U LD50 ... XEOMIN (100 LD50 UNIT) …

Aprotinin

Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI). Since it demonstrates the capacity to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and liver surgery. For this use, it is typically administered by injection. The goal...
Approved
Investigational
Withdrawn
Matched Description: … to slow fibrinolysis, it has been employed to reduce bleeding during complex surgery such as heart and ... was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Trasylol Inj 10000 Kiu/ml …

Pyritinol

Pyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … เมโมนอล 100 ... ENCEFABOL 100 MG …

Cenobamate

Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.[A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABAA and inhibits voltage gated sodium channels. Cenobamate was granted FDA approval on 21 November 2019.
Approved
Investigational
Matched Description: … inhibits voltage gated sodium channels. ... Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial ... of action has not been described in the literature, though it positively modulates GABAA and …
Matched Categories: … Voltage-Gated Sodium Channel Blockers …
Matched Products: … XCOPRI TITRATION PACK 50 mg, 100 mg ... XCOPRI MAINTENANCE PACK 100 mg, 150 mg …

Cefadroxil

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Salts name: … Cefadroxil sodium …
Matched Products: … CEFADROXIL HEXAL 1000MG ... Biodroxil 1000 mg - Filmtabletten ... CEFADROXIL SANDOZ 1000MG …

Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and ... Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality. …
Matched Categories: … X-Ray Contrast Activity ... X-Ray Contrast Media, Iodinated ... Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media …
Matched Products: … ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON , 100 ML ... OPAXOL 350 MGl/ML IA/IV ENJEKSİYONLUK ÇÖZELTİ, 100 ML ... IOBRIX INJ. 300 MG/ML ENJEKSIYON ICIN STERIL COZELTI 100 ML …

Doxepin

Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. ... [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer ... [L5977] Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. …
Matched Categories: … Antipruritics and Local Anesthetics ... Hypnotics and Sedatives ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … MAREEN 100MG ... DOXEPIN AL 100 ... Triadapin Cap 100mg …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LYNPARZA® 100 MG ... LYNPARZA (100 MG TABLET) ... LYNPARZA FILM-COATED TABLET 100MG …

Triethylenetetramine

Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Description: … Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective ... are de-coppered and tolerant to [penicillamine]. ... It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … NOVİLS 250 MG SERT KAPSÜL, 100 ADET ... TRENDİN 250 MG SERT KAPSÜL, 100 ADET ... WİLENTİN 250 MG SERT KAPSÜL, 100 ADET …

Infliximab

Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … inflammatory diseases and induction of remission in patients who have had an inadequate response to ... Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody ... composed of human constant (75%) and murine variable (25%) regions [A31469]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … FLIXABI 100MG ... REMSIMA 100MG ... REMICADE 100MG …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic colorectal cancer with ... /mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and ... cells; it is responsible for regulating epithelial tissue development and homeostasis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 100 MG/20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... ERBITUX 500 MG/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …

Naftidrofuryl

Experimental
Matched Products: … NAFTILONG 100 ... DUSODRIL RETARD 100MG ... NAFTI RATIOPHARM 100MG REK …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … ASTERAL SUBLINGUAL TABLET, 1000 ADET …

Isoflurane

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Approved
Vet approved
Matched Products: … ISOFLURANE USP %100 İNHALASYON ÇÖZELTİSİ, 100 ML ... ISOFLUDEM 100 ML SISE ... ISORANE (Isoflurane Inhalation Liquid 100% V/V) …
Displaying drugs 1401 - 1425 of 1737 in total