Displaying drugs 1451 - 1475 of 2943 in total
Benoxaprofen
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
OMS906
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease …
Anisotropine methylbromide
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched International brands: … Valpin …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
Matched Description: … gastric acid secretion. ... gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. …
N,N-dimethylarginine
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a...
Experimental
Matched Synonyms: … dimethyl-L-arginine ... NG,NG-Dimethyl-L-arginine …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Matched Description: … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and ... , a conditionally-essential amino acid. ... continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Matched Description: … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and ... , a conditionally-essential amino acid. ... continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Protamine sulfate
Since it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps the only viable option for reversing the anticoagulant effect of heparin use for over 77 years [A174778,...
Approved
Matched Description: … kidney tissue damage, and anaphylactic reaction, amongst others [A174778, L5371]. ... reversal predominantly via the formation of an inactive complex between the anionic nature of heparin and ... but genuinely severe adverse effects that include systemic hypotension, pulmonary hypertension, liver and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PROMIN 5000 IU/5 ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PROMIN 5000 IU/5 ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL …
L-Pentahomoserine
Experimental
Matched Synonyms: … 5-Hydroxy-2-aminovaleric acid ... L-alpha-Amino-delta-hydroxyvaleric acid …
Matched Iupac: … (2S)-2-amino-5-hydroxypentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-5-hydroxypentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Iron (III) oxide adipate
Investigational
Matched Synonyms: … Adipic acid ion (2-) ... Hexanedioic acid, ion(2-) …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Coproporphyrinogen III
Experimental
Matched Synonyms: … 3,8,13,17-tetramethyl-5,10,15,20,22,24-hexahydroporphyrin-2,7,12,18-tetrapropionic acid ... 5,10,15,20,22,24-hexahydro-3,8,13,17-tetramethyl-21H,23H-porphine-2,7,12,18-tetrapropanoic acid …
Matched Iupac: … tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(20),3,5,8,10,13,15,18-octaen-4-yl]propanoic acid …
Matched Iupac: … tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(20),3,5,8,10,13,15,18-octaen-4-yl]propanoic acid …
Sodium ascorbate
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid sodium salt ... L-Ascorbic acid sodium salt ... L-Ascorbic acid, monosodium salt …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Carboxylic Acids ... Sugar Acids …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Carboxylic Acids ... Sugar Acids …
Suprofen
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … p-2-thenoylhydratropic acid ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids …
Alfuzosin
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads ... to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. ... The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to …
Matched Categories: … Genito Urinary System and Sex Hormones ... alfuzosin and finasteride …
Matched Products: … ALFUZOSIN ACINO 5MG RET ... ALFUZOSIN ACINO 10MG RET …
Matched Categories: … Genito Urinary System and Sex Hormones ... alfuzosin and finasteride …
Matched Products: … ALFUZOSIN ACINO 5MG RET ... ALFUZOSIN ACINO 10MG RET …
KH064
Experimental
Matched Synonyms: … (S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid ... 5-(4-Benzyloxyphenyl)-4S-(7-phenylheptanoylamino)pentanoic acid …
Matched Iupac: … (4S)-5-[4-(benzyloxy)phenyl]-4-(7-phenylheptanamido)pentanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … (4S)-5-[4-(benzyloxy)phenyl]-4-(7-phenylheptanamido)pentanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Fentiazac
Experimental
Matched Synonyms: … 4-(4-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid ... 4-(p-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid …
Matched Iupac: … 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Acids, Acyclic …
Matched Iupac: … 2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain ... Acids, Acyclic …
Mesalazine
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Synonyms: … 5-aminosalicylic acid ... m-Aminosalicylic acid …
Matched Iupac: … 5-amino-2-hydroxybenzoic acid …
Matched Description: … drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. ... An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine …
Matched Categories: … Aminosalicylic Acids …
Matched Products: … Ntp-5-aminosalicylic Acid …
Matched Iupac: … 5-amino-2-hydroxybenzoic acid …
Matched Description: … drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. ... An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine …
Matched Categories: … Aminosalicylic Acids …
Matched Products: … Ntp-5-aminosalicylic Acid …
Meprobamate
A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated)....
Approved
Illicit
Matched Synonyms: … Meprobamic acid …
Matched Description: … A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses ... It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia …
Matched Categories: … Hypnotics and Sedatives ... Acids, Acyclic ... Carboxylic Acids …
Matched Description: … A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses ... It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia …
Matched Categories: … Hypnotics and Sedatives ... Acids, Acyclic ... Carboxylic Acids …
L-gulonic acid 6-phosphate
Experimental
Matched Synonyms: … 6-O-phosphono-L-gulonic acid …
Matched Name: … L-gulonic acid 6-phosphate …
Matched Iupac: … (2S,3S,4R,5S)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid …
Matched Name: … L-gulonic acid 6-phosphate …
Matched Iupac: … (2S,3S,4R,5S)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexanoic acid …
Potassium perchlorate
Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags . The use of potassium perchlorate as a component in sealing gaskets for food containers...
Approved
Investigational
Matched Synonyms: … Perchloric acid, potassium salt …
Matched Description: … Potassium is most commonly used in flares and automobile airbags [A32609]. ... Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates ... perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and …
Matched Categories: … Sex Hormones and Insulins ... Acids ... Acids, Noncarboxylic …
Matched Description: … Potassium is most commonly used in flares and automobile airbags [A32609]. ... Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates ... perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and …
Matched Categories: … Sex Hormones and Insulins ... Acids ... Acids, Noncarboxylic …
Zinc citrate
Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration .
Investigational
Matched Synonyms: … Citric acid, zinc salt …
Matched Description: … It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is ... Zinc citrate is a zinc salt of citric acid. …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Palm Springs Multvit and Min Tab ... Children's Chewable Vit and Min Tab …
Matched Description: … It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is ... Zinc citrate is a zinc salt of citric acid. …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Palm Springs Multvit and Min Tab ... Children's Chewable Vit and Min Tab …
Coenzyme M
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-mercaptoethanesulfonic acid ... 2-mercaptoethanesulphonic acid ... β-mercaptoethanesulfonic acid …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is ... used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations ... Alkanesulfonic Acids ... Sulfur Acids ... Sulfonic Acids …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is ... used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations ... Alkanesulfonic Acids ... Sulfur Acids ... Sulfonic Acids …
Fosinoprilat
Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Experimental
Matched Synonyms: … Fosinoprilic acid …
Matched Iupac: … (2S,4S)-4-cyclohexyl-1-{2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylic acid …
Matched Description: … It binds zinc with phosphinic acid group. ... Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Phosphinic Acids …
Matched Iupac: … (2S,4S)-4-cyclohexyl-1-{2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylic acid …
Matched Description: … It binds zinc with phosphinic acid group. ... Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Phosphinic Acids …
Nano-diamino-tetrac
Investigational
Matched Synonyms: … nano-diamino-tetraiodothyroacetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Ceftobiprole medocaril
Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA).
The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Synonyms: … Ceftobiprole medocaril free acid …
Matched Iupac: … -2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and …
Matched Iupac: … -2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and …
Sodium arsenite
Investigational
Matched Synonyms: … Arsenious acid, sodium salt ... Arsenenous acid, sodium salt (1:1) ... Arsenious acid, monosodium salt …
Butalbital
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Synonyms: … Allylbarbituric acid ... iso-butylallylbarbituric acid ... 5-allyl-5-isobutylbarbituric acid …
Matched Description: … Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... at position 5 are substituted by an allyl group and an isobutyl group. ... , acetaminophen, aspirin, and caffeine. …
Matched Mixtures name: … Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Butalbital, Aspirin, and Caffeine ... Butalbital, Aspirin and Caffeine …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... at position 5 are substituted by an allyl group and an isobutyl group. ... , acetaminophen, aspirin, and caffeine. …
Matched Mixtures name: … Butalbital, Aspirin, Caffeine and Codeine Phosphate ... Butalbital, Aspirin, and Caffeine ... Butalbital, Aspirin and Caffeine …
Matched Categories: … Hypnotics and Sedatives …
CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE
Experimental
Matched Name: … CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE …
Displaying drugs 1451 - 1475 of 2943 in total