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Displaying drugs 126 - 150 of 6371 in total
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5- …
Matched Iupac: … 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Salts cas: … 123171-59-5
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Mixtures name: … BROCRIPTIN® 10 MG/ 5 MG ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... BRONCHOREST 10 MG/5 MG KAPSÜL ,30 KAPSÜL …
Matched Products: … AIRFIX 5 MG CIGNEME TABLETI, 56 ADET ... AIRMOL 5 MG CIGNEME TABLETI, 56 ADET ... AIRMOL 10 MG FILM TABLET, 56 ADET …
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Mixtures name: … XİGDUO XR 5 MG/ 1000 MG FİLM KAPLI TABLET, 56 TABLET ... XIGDUO XR TABLET 5/1000MG ... XIGDUO XR (TABLETS 5 MG/1000 MG) …
Matched Products: … DAPAGLEZE 5 MG FILM KAPLI TABLET, 28 ADET ... Dapagliflozin TAD 5 mg Filmtabletten ... DAPAGLEZE 5 MG FILM KAPLI TABLET, 90 ADET …
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Mixtures name: … 5%Minoxidil Hair Growth Serum …
Matched Products: … Curatin 5 mg - Tabletten ... HIOTIN 5 MG TABLET,TABLET, 60 ADET ... HIOTIN 5 MG TABLET,TABLET, 90 ADET …
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn
Matched Products: … SUNVEPRA 100 MG KAPSÜL, 56 ADET …
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Salts cas: … 928659-70-5
Matched Products: … CERDELGA 84 MG SERT KAPSÜL, 56 ADET …
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Approved
Investigational
Nutraceutical
Matched Synonyms: … 5-L-Glutamyl-L-cysteinylglycine …
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others. As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Products: … CALQUENCE 100 MG SERT KAPSÜL, 56 ADET …
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … -12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5- …
Matched Products: … AZEC 30 MG/5 ML ... PAXIRA ® 30 MG/ 5 ML ... TAXOL 30 MG/5 ML FLAKON, 1 ADET …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Iupac: … 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl …
Matched Mixtures name: … UNISIA 8 MG/5 MG ... UNISIA 8 MG/5 MG ... CANDAM ® H 5/32/12.5 …
Matched Products: … UCAND 4 MG TABLET, 56 ADET ... UCAND 8 MG TABLET, 56 ADET ... CANTAB 4 MG TABLET, 56 ADET …
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN …
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … 3,4',5-trihydroxystilbene-3-β-d-glucoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine …
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Products: … DULOXX 60 MG KAPSUL, 56 ADET ... DULOXAT 30 MG KAPSÜL, 56 ADET ... DULAXAT 60 MG KAPSÜL, 56 ADET …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Products: … LUDIOMIL 75 MG TABLET, 56 ADET …
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Synonyms: … 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Products: … PANTPAS 40 MG TABLET, 56 ADET ... PROTINUM 40 MG ENTERIK TABLET, 56 ADET ... GASPAZOL 40 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 5 FLAKON …
Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Products: … BEKLAMEN 4 MG EFERVESAN TABLET, 56 ADET ... BEKLAMEN 8 MG EFERVESAN TABLET, 56 ADET …
Approved
Matched Mixtures name: … Plasma-lyte 56 5% Dextrose Inj ... Normosol-M & 5% Dextrose ... AMINOPLASMAL-5% E INFUSION …
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1D Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … โปรโคมิล 5 มก. ... Yocon-Glenwood Tabletten 5 mg …
NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by...
Approved
Nutraceutical
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy] ... ({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic …
Matched Description: … -diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. ... reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5' …
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. ... Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention ... It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that …
Matched Categories: … Serotonin 5-HT3 Receptor Antagonists ... Antiemetic Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … ZİAXE 250 MCG / 5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ML ... PALOCIP® 250 MCG/5 ML ... PELATOS 250 MCG/5 ML I.V. ENJEKSİYONLUK ÇÖZELTİ …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … Plasma-lyte 56 5% Dextrose Inj ... ดี-5-1/5เอส ... DEXTROSE 5% IN 1/5 STR. SALINE …
Matched Products: … Dextrose Inj 5% ... GLUCOSIO 5% BAXTER ... 5% Dextrose Injection USP …
Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. It was approved by the FDA after being given the status of priority review for on July 7, 2015....
Approved
Matched Iupac: … 3-{[(2S,4R)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid …
Matched Mixtures name: … ONEPTUS 49 MG/51 MG FILM KAPLI TABLET, 56 ADET ... ONEPTUS 97 MG/103 MG FILM KAPLI TABLET, 56 ADET …
Displaying drugs 126 - 150 of 6371 in total