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Displaying drugs 126 - 150 of 10666 in total

Indigotindisulfonic acid

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to ... [A251405] Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was ... first approved for use in the United States in 2001. ... of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of …
Matched Products: … CYCLOCAPS FORMOTERO12UG+IN ... FORMATRIS 6UG NOV IN+2PX60 ... FORMATRIS 6UG NOV IN+3PX60 …

Talimogene laherparepvec

Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. It specifically replicates within...
Approved
Experimental
Investigational
Matched Description: … Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, ... subcutaneous, and nodal lesions in patients with recurrent melanoma. ... It was approved by the FDA in 2015 under the market name Imlygic. …
Matched Categories: … Antineoplastic cell and gene therapy …

Lovastatin

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Description: … endogenous production of cholesterol in the liver. ... HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the ... has resulted in this class becoming one of the most widely prescribed medications in North America. …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Compounds used in a research, industrial, or household setting …

Enprofylline

Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Description: … Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular ... Enprofylline is a derivative of theophylline which shares bronchodilator properties. ... Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable …

Zopiclone

Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Synonyms: … 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate …
Matched Iupac: … 6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Description: … Zopiclone is a novel hypnotic agent used in the treatment of insomnia. ... Its mechanism of action is based on modulating benzodiazepine receptors. ... In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … projection system in the brain arising from the locus ceruleus. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse ... It is also found in plants and is used pharmacologically as a sympathomimetic. …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection …

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Iupac: … dimethylhept-3-en-2-yl]-9a,11a-dimethyl-1H,2H,3H,3aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Description: … A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably ... AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans ... It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant ... Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis …
Matched Mixtures name: … Super 7 Vitamin and Mineral Supplement ... Tracel Injektionslösung in einer Fertigspritze …

Insulin beef

Insulin beef has been discontinued in the US and Canada since 2017.
Approved
Matched Description: … Insulin beef has been discontinued in the US and Canada since 2017.[L10827] …
Matched Categories: … Drugs Used in Diabetes …

Influenza B virus B/Victoria/705/2018 BVR-11 antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory ... using a combination of medications. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia …
Matched Products: … FRESOFOL MCT/LCT EMULSION FOR INJECTION OR INFUSION IN PRE-FILLED SYRINGE 2% ... Propofol "Fresenius" 1 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze ... Propofol "Fresenius" 2 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the ... of this product. …
Matched Mixtures name: … easyangin Spray zur Anwendung in der Mundhöhle ... Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Chlorhexamed 1% - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed Direkt 1 % - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed forte 2 mg/ml Dentallösung zur Anwendung in der Zahnarztpraxis …

Tetradecyl hydrogen sulfate (ester)

Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched Synonyms: … 7-Ethyl-2-methyl-4-undecanol sulfate …
Matched Iupac: … [(7-ethyl-2-methylundecan-4-yl)oxy]sulfonic acid …
Matched Description: … of injecting a 1% solution into spider angiomas in 144 patients was made. ... Also noted was an unspecified number of episodes of epidermal necrosis without significant long-term ... Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in …

Zaleplon

Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Synonyms: … 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Description: … Zaleplon is a schedule IV drug in the United States. ... Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of …

Calendula officinalis flower

Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Description: … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... Heparin Sodium In 0.9% Sodium Chloride Injection ... Heparin Sodium In 5% Dextrose Injection, 25000unit/500ml …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Iupac: … acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Mixtures name: … Minoxidil 7% / Progesterone 0.1% ... Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% ... Fluocinolone Acetonide 0.01% / Minoxidil 7% / Progesterone 0.1% …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 7 ADET ... Gesterol In Oil-liq Im 50mg/ml ... Progedex 25 mg Injektionslösung in einer Fertigspritze …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … pending approval for the treatment of bipolar disorder in the United States. ... Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Iupac: … dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19}.0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7- …
Matched Description: … In its statement, the FDA has mentioned that increased risk of venous thromboembolism with oral contraceptives ... Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination ... [A182543,A182552] In 2012, however, a safety statement by the FDA concluded that the increase in the …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Durlobactam

Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE ... SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER …
Matched Iupac: … [(1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]oxidanesulfonic acid …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of ... It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Description: … quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in …
Matched Categories: … combinations of sulfonamides …

Ciclopirox

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Description: … synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. ... In particular, the agent is especially effective in treating Tinea versicolor. ... Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …

Lactitol

Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … the treatment of hepatic encephalopathy in patients with cirrhosis. ... chronic idiopathic constipation in February 2020. ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 126 - 150 of 10666 in total