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Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6a individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Investigational
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... the capsular antigens of *Streptococcus pneumoniae* serotype 6a individually conjugated to the CRM197 …
Matched Mixtures name: … Prevnar 13 ... Prevnar 13 ... Prevnar 13
Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Description: … genotype 1a patients and Y93H in genotype 3 patients. ... Binding to the N-terminus of the D1 domain of NS5A prevents its interaction with host cell proteins and ... According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is …
Matched Categories: … Antivirals for treatment of HCV infections …
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate ... alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester …
Matched Iupac: … (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate …
Matched Description: … Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar ... As an acetylcholine analogue, scopolamine can antagonize muscarinic acetylcholine receptors (mAChRs) in ... [A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Products: … Curocef 1500 mg Pulver zur Herstellung einer Infusionslösung in einer Einzelampulle …
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds. It has been...
Approved
Matched Description: … Coal tar is a brown or black liquid of extremely high viscosity. ... Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and ... It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea …
Matched Mixtures name: … Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner …
Matched Products: … Psoriasin In-Shower Treatment ... COAL TAR SOLUTION 10% IN AQUEOUS CREAM ... COAL TAR SOLUTION 5% IN AQUEOUS CREAM …
Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 9v individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Mixtures name: … Prevnar 13 ... Prevnar 13 ... เพรฟนาร์ 13
Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 14 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Mixtures name: … Prevnar 13 ... Prevnar 13 ... เพรฟนาร์ 13
Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 18c individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae ... It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Mixtures name: … Prevnar 13 ... Prevnar 13 ... เพรฟนาร์ 13
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … This drug is unique from others in this class due to its rapid onset of effects and short duration of ... [L45098] In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive ... intermittent, stereotypic seizure episodes in patients 12 years of age and older. …
Matched Products: … Midazolam in Sodium Chloride ... Midazolam In Sodium Chloride ... Epistatus 5 mg Lösung zur Anwendung in der Mundhöhle …
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Iupac: … (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7- …
Matched Description: … Similar to echinocandins, ibrexafungerp targets the fungal β-1,3-glucan synthase, which is not present in ... humans, limiting the chance of renal or hepatic toxicity. ... or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of
Tabelecleucel is an innovative therapy that uses Epstein-Barr virus (EBV)-specific allogeneic cytotoxic T cells (CTLs). It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV). Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers....
Approved
Investigational
Matched Description: … [A253292,A253297,L43557] In October 2022, the EMA's Committee for Medicinal Products for Human Use ... (CHMP) recommended tabelecleucel be granted marketing authorization for the treatment of adult and pediatric …
Matched Categories: … Antineoplastic cell and gene therapy …
Lovotibeglogene autotemcel consists of autologous hematopoietic stem and progenitor cells transduced with the BB305 lentiviral vector encoding a modified β-globin gene. Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (βA-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as wild type hemoglobin. Additionally,...
Approved
Investigational
Matched Description: … two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients 12 ... sickle cell disease (SCD) in patients ages 12 and older who have a history of vaso-occlusive events. ... Specifically, lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β …
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.
Approved
Matched Description: … Topical antiseptic used mainly in wound dressings. …
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. ... trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in
Matched Mixtures name: … Nitroglycerin In 5% Dextrose Inj.-400mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-200mcg/ml ... Nitroglycerin In 5% Dextrose Inj.-100mcg/ml …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Vasodilators Used in Cardiac Diseases ... Compounds used in a research, industrial, or household setting …
Matched Products: … Nitroglycerin in Dextrose ... Nitroglycerin In Dextrose …
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory ... multiple myeloma in treatment-experienced patients. ... variable in its presentation - some patients may remain entirely asymptomatic, while others may experience …
Matched Categories: … Antineoplastic cell and gene therapy …
Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 …
Matched Description: … is beneficial in the treatment of migraine. ... of migraine with or without aura in adults. ... Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. …
Matched Salts cas: … 1414976-20-7
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists ... Receptors, Calcitonin Gene-Related Peptide, antagonists & inhibitors …
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Iupac: … (3R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl …
Matched Description: … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon ... to improve control of blood sugar[FDA label,A2255]. ... Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise …
Matched Salts cas: … 837430-24-7
Matched Categories: … Drugs Used in Diabetes …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Ancestim is a non-glycosylated recombinant methionyl human stem cell factor. It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine . Ancestim was...
Approved
Investigational
Withdrawn
Matched Description: … [T68] It was also approved by Health Canada in 1999 but it is currently under the status of canceled ... Ancestim was developed by Amgen and sold to Biovitrium in December 2008. ... It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes. …
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Iupac: … -5-methoxy-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraene-10-carboxylate ... )-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy ... methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(1R,13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl …
Matched Description: … because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical ... It is marketed under several brand names, many of which have different formulations such as Marqibo ( ... Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, …
Matched Products: … CYTOCRISTIN AQUEOUS (VL OF 1ML) …
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration …
Matched Mixtures name: … Phaze 13 Light N' Block Pigment Cream ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Description: … It is an ester of salicylic acid and 2-ethylhexanol. ... Octyl salicylate is used to augment the UVB protection in a sunscreen. ... It covers wavelength in the range 295-315 nm, peak at 307-310 nm. …
Matched Mixtures name: … Olay Total Effects 7-IN-1 Anti-aging Uv Moisturizer Plus Touch Of Foundation ... 7 In One Cc Tone Correcting ... CareOne 7-in-1 Anti-Aging Vitamin …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Mixtures name: … Dobutamine Hydrochloride in Dextrose …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Dobutamine in Dextrose ... Dobutamine Hydrochloride in Dextrose …
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Synonyms: … 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one ... 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one ... 7-nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Displaying drugs 126 - 150 of 11315 in total