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Displaying drugs 1601 - 1625 of 1915 in total

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ZYTIGA FILM-COATED TABLET 500MG ... ZYTIGA 500 MG (FILM-COATED TABLETS) ... ZYTIGA 500mg Film-Coated Tablet …

Trametinib

Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and ... [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission ... currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors ... Mitogen-activated protein kinase (MEK) inhibitors …
Matched Products: … MEKINIST FILM-COATED TABLETS 2MG ... MEKINIST FILM-COATED TABLETS 0.5MG ... MEKINIST 2 MG FILM KAPLI TABLET ,7 TABLET …

Prasterone sulfate

DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.
Investigational
Matched Synonyms: … Androst-5-en-17-on-3beta-yl sulfuric acid …
Matched Description: … ACTH and prolactin. ... DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of …
Matched Salts name: … Prasterone sodium sulfate anhydrous …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Entecavir

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... Food and Drug Administration (FDA) in March 2005. ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTEFIL 1 MG FILM TABLET ,FILM TABLET, 30 ADET ... ENTEFIL 0.5 MG FILM TABLET ,FILM TABLET, 30 ADET ... ENTEVIR FILM-COATED TABLET 1MG …

Orthosiphon aristatus leaf

Approved
Experimental
Matched Synonyms: … Shen cha leaf …

Irbesartan

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Mixtures name: … Irbesartan and Hydrochlorothiazide ... Irbesartan and Hydrochlorothiazide ... Irbesartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... irbesartan and diuretics ... irbesartan and amlodipine ... irbesartan, amlodipine and hydrochlorothiazide …
Matched Products: … ERBETAN FILM-COATED TABLET 150MG ... ERBETAN FILM-COATED TABLET 300MG ... Tensiber Film Coated Tablet 150mg …

Solifenacin

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Description: … muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones ... tamsulosin and solifenacin …
Matched Products: … VESICARE 5 MG FILM-COATED TABLET ... VESICARE 10 MG FILM-COATED TABLET ... BLADITON FILM COATED TABLETS 5MG …

Brexpiprazole

Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Description: … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called ... It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. ... It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors. …
Matched Categories: … Sulfur Compounds …
Matched Products: … Rexulti 1mg film-coated tablets ... Rexulti 4mg film-coated tablets ... Rexulti 3mg film-coated tablets …

Etoricoxib

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Sulfur Compounds …
Matched Products: … Coxitor 90mg Film-coated Tablets ... Coxitor 120mg Film-coated Tablets ... BIOCOXIB 90MG Film Coated Tablet …

Levocetirizine

Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Mixtures name: … LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET ... LEPIXOS 5 MG/10 MG FILM TABLET ,60 ADET ... LEPIXOS 5 MG/10 MG FILM TABLET ,90 ADET …
Matched Categories: … Cetirizine and isomer …
Matched Products: … XYZAL 5MG FILM COATED TABLET ... XYZAL 5 MG FİLM TABLET, 40 ADET ... XYZAL FILM-COATED TABLET 5 MG …

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise ... The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon …
Matched Mixtures name: … Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride …
Matched Salts name: … Sitagliptin phosphate …
Matched Categories: … Protease Inhibitors ... Alimentary Tract and Metabolism ... metformin and sitagliptin ... sitagliptin and simvastatin ... sitagliptin and ertugliflozin …
Matched Products: … PTİAGLİN 100 MG FİLM KAPLI TABLET ... İVOBRA 5 MG FİLM KAPLI TABLET, 56 ADET ... Sitavia Film Coated Tablet 100mg …

Rivaroxaban

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. ... The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011. …
Matched Categories: … Blood and Blood Forming Organs ... rivaroxaban and acetylsalicylic acid ... Sulfur Compounds ... Protease Inhibitors ... Serine Protease Inhibitors …
Matched Products: … Xarelto 2.5mg Film-Coated Tablets ... Rivax 10mg Film Coated Tablets ... Rivax 20mg Film Coated Tablets …

Perampanel

Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Description: … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for ... The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and …
Matched Products: … FYCOMPA FILM-COATED TABLET 6MG ... FYCOMPA FILM-COATED TABLET 12MG ... FYCOMPA FILM-COATED TABLET 8MG …

Pazopanib

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
Approved
Matched Description: … It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009. ... Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds ... Protein Kinase Inhibitors …
Matched Products: … VOTRIENT FILM-COATED TABLET 200MG ... VOTRIENT FILM-COATED TABLET 400MG ... VOTRIENT 200 MG FİLM KAPLI TABLET, 30 ADET …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts ... Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and …
Matched Mixtures name: … BIPRETERAX 10 MG/2.5 MG FİLM KAPLI TABLET, 30 ADET ... TRIPLIXAM FILM COATED TABLET 10 mg/ 2.5 mg/ 5 mg ... BIPRETERAX 5 MG/1,25 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Sulfur Compounds ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …
Matched Products: … FLUPAMID 2.5 MG FİLM TABLET, 30 TABLET ... FLUBEST 2,5 MG FILM KAPLI TABLET, 20 ADET ... FLUDIN 2.5 MG FILM TABLET, 20 ADET …

Hydroxychloroquine

Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and ... [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … HYDROXYCHLOROQUINE SULFATE film coated ... PLAQUENIL 200 MG FILM KAPLI TABLET, 60 ADET ... PLAQUENIL 200 MG FILM KAPLI TABLET, 100 ADET …

Sulfamerazine

A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-Sulfa-4-methylpyrimidine …
Matched Salts name: … Sulfamerazine sodium …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... Gynecological Antiinfectives and Antiseptics ... sulfamerazine and trimethoprim …

Venetoclax

Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic ... chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who ... cell death) process [A18565], [A18566]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Matched Products: … VENCLEXTA FILM-COATED TABLET 10MG ... VENCLEXTA FILM-COATED TABLET 50MG ... VENCLEXTA FILM-COATED TABLET 100MG …

Dolutegravir

Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … The effect of this drug has no homology in human host cells, which gives it excellent tolerability and ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET ... TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,FILM KAPLI TABLET, 30 ADET ... TRIUMEQ FILM COATED TABLET 50mg/600mg/300mg …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … Tivicay 50mg Film-Coated Tablets ... TIVICAY FILM-COATED TABLET 25MG ... TIVICAY FILM-COATED TABLET 10MG …

Desloratadine

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... AIRCOMB 5/10 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Loratadine and derivatives …
Matched Products: … AXIVOL 5 MG FILM TABLET, 10 ADET ... AXIVOL 5 MG FILM TABLET, 30 ADET ... DESADYNE 5 MG FILM TABLET, 30 ADET …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET …

Cefprozil

Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Approved
Matched Description: … skin, bronchitis, and others. ... antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and …
Matched Categories: … Sulfur Compounds …
Matched Products: … PREFIX 250 MG FILM TABLET, 10 ADET ... PREFIX 250 MG FILM TABLET, 14 ADET ... PREFIX 250 MG FILM TABLET, 20 ADET …

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation...
Investigational
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … DAPIGRA 30 MG FILM TABLET ,3 FILM TABLET ... DAPIGRA 30 MG FILM TABLET ,6 FILM TABLET ... DAPIGRA 60 MG FILM TABLET ,3 FILM TABLET …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Mixtures name: … INDEXPA SR 75/300MG FILM KAPLI TABLET, 10 SR FILM KAPLI TABLET ... INDEXPA SR 75/300MG FILM KAPLI TABLET, 20 SR FILM KAPLI TABLET ... SKUDEXA FILM-COATED TABLET 75 MG/25 MG …
Matched Categories: … Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... tramadol and dexketoprofen ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 10 ADET ... SERTOFEN 25 MG FILM TABLET ,FILM TABLET, 20 ADET ... KETESSE 25MG FILM COATED TABLET …

Alteplase

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Displaying drugs 1601 - 1625 of 1915 in total