Displaying drugs 1626 - 1650 of 2325 in total
Timolol
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … Timolol anhydrous …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... timolol, thiazides and other diuretics …
Matched Products: … Dom-timolol ... MALEATO DE TIMOLOL AL 0.5% ... MALEATO DE TIMOLOL 0.5% SOLUCIÓN OFTALMICA …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... timolol, thiazides and other diuretics …
Matched Products: … Dom-timolol ... MALEATO DE TIMOLOL AL 0.5% ... MALEATO DE TIMOLOL 0.5% SOLUCIÓN OFTALMICA …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … Mercaptopurine anhydrous …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Lincomycin
Lincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use.[A190657, A190621]
Lincomycin was approved...
Approved
Vet approved
Matched Description: … to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains in use. ... Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due …
Matched Salts name: … Lincomycin hydrochloride ... Lincomycin hydrochloride monohydrate …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Products: … Lincomycin Hydrochloride ... Lincomycin hydrochloride …
Matched Salts name: … Lincomycin hydrochloride ... Lincomycin hydrochloride monohydrate …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Products: … Lincomycin Hydrochloride ... Lincomycin hydrochloride …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate ... 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
Azelastine
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Description: … phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and ... vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis. ... racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and …
Matched Mixtures name: … DYMISTA D ... Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Salts name: … Azelastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Azelastine Hydrochloride ... Azelastine Hydrochloride Ophthalmic Solution 0.05% …
Matched Mixtures name: … DYMISTA D ... Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Salts name: … Azelastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Azelastine Hydrochloride ... Azelastine Hydrochloride Ophthalmic Solution 0.05% …
Lurasidone
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts name: … Lurasidone hydrochloride …
Matched Categories: … Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-2 Receptor Antagonists …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …
Matched Salts name: … Lurasidone hydrochloride …
Matched Categories: … Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-2 Receptor Antagonists …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …
Beta-D-Glucopyranose Spirohydantoin
Experimental
Matched Name: … Beta-D-Glucopyranose Spirohydantoin …
ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE
Experimental
Matched Name: … ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE …
D-fluoromethyltyrosine F-18
D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety, Tolerability and Diagnostic Performance of BAY86-9596 in Patients With Non-small Cell Lung Cancer, Breast Cancer, Head and Neck Cancer and Patients With Inflammations).
Investigational
Matched Name: … D-fluoromethyltyrosine F-18 …
Matched Description: … D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for ... Breast Cancer, Head and Neck Cancer and Patients With Inflammations). ... Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety …
Matched Description: … D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for ... Breast Cancer, Head and Neck Cancer and Patients With Inflammations). ... Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety …
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine …
Matched Iupac: … chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Iupac: … chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Nerofe
Nerofe is under investigation in clinical trial NCT03059615 (A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS).
Investigational
Matched Synonyms: … WWTFFLPSTLWERK, (ALL D)- ... TRP-TRP-THR-PHE-PHE-LEU-PRO-SER-THR-LEU-TRP-GLU-ARG-LYS, (ALL D)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lysergic acid diethylamide
Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD...
Illicit
Investigational
Withdrawn
Matched Synonyms: … D-lysergic acid diethylamide ... N,N-diethyl-D-lysergamide …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and …
Matched Categories: … Ergot Alkaloids and Derivatives …
Prednisolone
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Sex Hormones and Insulins ... prednisolone and mydriatics …
Matched Products: … SCHERISOLONA® TABLETAS DE 5 MG ... STERILE PREDNISOLONE ACETATE SUSPENSION …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Sex Hormones and Insulins ... prednisolone and mydriatics …
Matched Products: … SCHERISOLONA® TABLETAS DE 5 MG ... STERILE PREDNISOLONE ACETATE SUSPENSION …
TOL-101
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Immucillin-G
Experimental
Matched Synonyms: … (1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-D-ribitol …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
2-Iminobiotin
Experimental
Investigational
Matched Synonyms: … Hexahydro-2-imino-1h-thieno(3,4-d)imidazole-4-pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride ... Dom-nortriptyline 10mg Capsules ... Dom-nortriptyline 25mg Capsules …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Salts name: … Nortriptyline hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride ... Dom-nortriptyline 10mg Capsules ... Dom-nortriptyline 25mg Capsules …
Carbon black
Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment with demonstrated adverse effects on pulmonary function. Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue and has been linked to carcinogenicity.[A263406, A263411, A263416]
Investigational
Matched Synonyms: … D&C black no. 2 ... DC BLACK NO. 2 ... D&C BLACK NO. 2 [II] …
Matched Description: … inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and …
Matched Description: … inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and …
Edotreotide
Investigational
Matched Synonyms: … N-((4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacycoldodec-1-yl)acetyl-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryprophyl-l-lysyl-l-threonyl-n ... L-cysteinamide, n-((4,7,10-tris(carboxymetnyl)-1,4,7,10-tetraazacyclodec-1-yl)acetyl)-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-threonyl-n …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … alpha-difluoromethylornithine …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Salts name: … Eflornithine hydrochloride …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Salts name: … Eflornithine hydrochloride …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 1626 - 1650 of 2325 in total