Displaying drugs 151 - 175 of 5886 in total
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN …
Alemtuzumab
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … lymphocytic leukemia (B-CLL). ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing …
Matched Products: … MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP) …
Matched Products: … MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP) …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b) ... 12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b) …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Categories: … GABA-B Receptor Agonists …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Categories: … GABA-B Receptor Agonists …
Bisoprolol
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol ... (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Products: … B-BETA …
Matched Iupac: … 1-[(propan-2-yl)amino]-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol …
Matched Products: … B-BETA …
Peanut
Peanut allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … PALFORZIA (Level 3) ... PALFORZIA (Level 3) ... PALFORZIA (Level 7) …
Matched Products: … PALFORZIA (Level 1) ... PALFORZIA (Level 2) ... PALFORZIA (Level 4) …
Matched Products: … PALFORZIA (Level 1) ... PALFORZIA (Level 2) ... PALFORZIA (Level 4) …
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen ... is not tumour-specific and can also be found in normal B-cells. ... Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (3 ADET) …
Tafasitamab
Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies. It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains an IgG1/2 hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity relative to non-engineered anti-CD19...
Approved
Investigational
Matched Description: … Tafasatimab is designed to bind to and block the activity of the CD19 surface antigen, which ultimately ... [L15302] Its relative ubiquity across different stages of B-cell development, including pre-B and mature ... B-lymphocytes,[L15292] as well as its presence in several B-cell malignancies (e.g. chronic lymphocytic …
Matched Categories: … Lymphoma, B-Cell …
Matched Categories: … Lymphoma, B-Cell …
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen ... found on the surface of normal and malignant B lymphocytes. ... FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however …
Matched Products: … RİXATHON 100MG/10ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 3 ADET …
Matched Products: … RİXATHON 100MG/10ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 3 ADET …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol ... 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Bromfenac
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Salts cas: … 120638-55-3 …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Salts cas: … 120638-55-3 …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies ... for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks in patients with genotype 2 and 3 …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies ... for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks in patients with genotype 2 and 3 …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Ibrexafungerp
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Synonyms: … enfumafungin derivative B-(1,3)-D-glucan synthestis inhibitor ... 8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3- …
Matched Iupac: … 6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3- …
Matched Iupac: … 6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3- …
Obinutuzumab
Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Bosutinib
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine …
Belimumab
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … the survival of B cells. ... stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. ... Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte …
Matched Categories: … Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Matched Categories: … Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Lipoic acid
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (R)-1,2-dithiolane-3-valeric acid ... (R)-1,2-Dithiolane-3-pentanoic acid …
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …
Matched Mixtures name: … Live-well™ MITOcare™ Liqfil™ Vegetable Capsule ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 30 ADET ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 90 ADET …
Matched Categories: … Vitamin B Complex …
Matched Iupac: … 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid …
Matched Mixtures name: … Live-well™ MITOcare™ Liqfil™ Vegetable Capsule ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 30 ADET ... TIOPATI-B 600 MG/250 MG/1 MG FILM TABLET, 90 ADET …
Matched Categories: … Vitamin B Complex …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(1-Phenylpropyl)-4-hydroxycoumarin ... 3-(1'-Phenyl-propyl)-4-oxycoumarin ... 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Products: … PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB ... PHENPRO RATIOPHARM 3 MG …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Products: … PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB ... PHENPRO RATIOPHARM 3 MG …
Cyanocobalamin
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Iupac: … {[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3- …
Matched Mixtures name: … Animi-3 ... BP Vit 3 ... Animi-3 with Vitamin D …
Matched Categories: … Vitamin B Complex ... Vitamin B 12, biosynthesis …
Matched Products: … B - 12 ... B-plex ... Vitamin B-12 Tablet …
Matched Mixtures name: … Animi-3 ... BP Vit 3 ... Animi-3 with Vitamin D …
Matched Categories: … Vitamin B Complex ... Vitamin B 12, biosynthesis …
Matched Products: … B - 12 ... B-plex ... Vitamin B-12 Tablet …
Sodium fluoride
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … Laura Lynn Extra Whitening Sensitive ... Live Better Extra Whitening ... Live Better Extra Whitening …
Matched Products: … Crest Complete Plus 3 in 1 ... Laura Lynn Anticavity ... Laura Lynn Anticavity Toothpaste …
Matched Products: … Crest Complete Plus 3 in 1 ... Laura Lynn Anticavity ... Laura Lynn Anticavity Toothpaste …
Teclistamab
Teclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug...
Approved
Investigational
Matched Description: … cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. ... IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B …
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Codeine
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Synonyms: … morphine 3-methyl ether ... morphine-3-methyl ether ... 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol …
Matched Mixtures name: … PROMEDYL-B LINCTUS ... Acet 3 ... Phenaphen No 3 Cap …
Matched Mixtures name: … PROMEDYL-B LINCTUS ... Acet 3 ... Phenaphen No 3 Cap …
Displaying drugs 151 - 175 of 5886 in total