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Displaying drugs 1726 - 1750 of 1909 in total
Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Approved
Investigational
Matched Description: … It has been approved in South Korea and will be marketed under the brand name Zydena. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfur Compounds …
Matched Products: … ZYDENA 100 MG FILM TABLET, 2 ADET ... ZYDENA 100 MG FILM TABLET, 4 ADET …
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Description: … treatment for these types of cancers as patients generally have better survival, side effect profiles, and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … NOLVADEX 10 MG FILM TABLET, 30 ADET ... NOLVADEX 10 MG FILM TABLET, 250 ADET ... TAMOXIT 20 MG FİLM KAPLI TABLET (TAMOFEN), 100 TABLET …
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … ZİLADONE 10 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 20 MG FİLM KAPLI TABLET, 30 ADET ... ZİLADONE 40 MG FİLM KAPLI TABLET, 30 ADET …
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Description: … anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and ... Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … TYKERB 250 MG FILM TABLET, 70 ADET ... TYKERB FILM-COATED TABLETS 250MG …
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... widely prescribed in the Netherlands, New Zealand, and the US. ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … IMPLICOR 50MG/5MG FILM-COATED TABLETS ... IMPLICOR 25MG/5MG FILM-COATED TABLETS ... IMPLICOR FILM-COATED TABLET 25 mg/5 mg …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and amlodipine …
Matched Products: … Metoprolol Tartrate film coated ... PROBLOK 100 MG FİLM TABLET, 20 ADET ... LOPRESOR 100 MG FILM TABLET, 20 ADET …
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Synonyms: … 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone …
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drospirenone/Ethinyl Estradiol/Levomefolate Calcium and Levomefolate Calcium ... Drospirenone/ethinyl estradiol/levomefolate calcium and levomefolate calcium ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol …
Matched Products: … SLINDA FILM-COATED TABLETS 4MG ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET ... ZLYNDA 4 MG FİLM KAPLI TABLET, 84 ADET …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer. ... uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation. ... generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and
Matched Categories: … Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … ELASTA 60mg FILM-COATED TABLETS ... Raloxon Film-coated Tablets 60 mg ... ROXIMAX 60 MG FİLM TABLET, 28 ADET …
Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … It was launched in the US in December 1994 and in Japan in June 1999. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … LUVOX 50MG FILM COATED TABLET ... LUVOX 100MG FILM COATED TABLET ... REVOXIN 50MG FILM TABLET, 30 ADET …
Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of...
Approved
Investigational
Matched Description: … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction ... encephalopathy recurrence; as well as diarrhea-predominant irritable bowel syndrome (IBS-D) in adult women and
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … HEPAZEC 550 MG FILM TABLET,56-FILM-TABLET ... XIFAXAN Film-coated Tablet 550mg ... COLIDUR 200 MG FILM TABLET, 24 ADET …
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Products: … MIANSERIN-REMEDICA 30mg Film-Coated Tablets ... MIANSERIN-REMEDICA 10mg Film-Coated Tablets ... TOLVON 30 MG FİLM KAPLI TABLET, 14 ADET …
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Description: … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does …
Matched Mixtures name: … Femoston Conti 1/5mg Film-Coated Tablet ... Femoston Conti 0.5mg/2.5mg Film Coated Tablet …
Matched Categories: … Genito Urinary System and Sex Hormones ... dydrogesterone and estrogen ... dydrogesterone and estrogen ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Progestogens and Estrogens, Sequential Preparations …
Matched Products: … DUPHASTON TABLET 10 mg (Film-coated) ... DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and
Matched Mixtures name: … TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET ... TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADET ... Atenolol and Chlorthalidone …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Beta Blocking Agents and Thiazides ... atenolol and nifedipine ... atenolol and thiazides ... atenolol and other diuretics …
Matched Products: … ATENOLOL - CT 50 MG FILM ... ATENOLOL - CT 100 MG FILM ... TERNOLOL 50 FILM-COATED TABLET …
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FEMMEX 25 MG FILM TABLET, FILM TABLET, 30 ADET ... EXACCORD 25 FILM COATED TABLET 25 MG ... EXEMESTANE STADA FILM COATED TABLET 25mg …
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... vulgaris. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SPYLACTON 50 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 100 MG FILM KAPLI TABLET, 20 ADET ... SPYLACTON 25 MG FILM TABLET, 20 ADET …
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Description: … antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and ... The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the ... mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … INSPRA 25MG FILM-COATED TABLETS ... INSPRA 50MG FILM-COATED TABLETS ... EPLEDAY 25 MG FILM KAPLI TABLET, 50 ADET …
Experimental
Investigational
Matched Salts name: … Calcium dobesilate ... Calcium dobesilate monohydrate …
Matched Categories: … Sulfur Acids ... Sulfur Compounds ... calcium dobesilate ... calcium dobesilate, combinations …
Matched Products: … DOXIUM 1000 MG FILM TABLET, 30 ADET ... DOXIUM 1000 MG FILM TABLET, 60 ADET ... MODET 1000 MG FILM KAPLI TABLET ,30 ADET …
Siponimod, also known as Mayzent, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a sphingosine-1-phosphate (S1P) receptor modulator and is thought to...
Approved
Investigational
Matched Description: … [L12171] This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought ... It was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020. ... , disrupting communication between the brain and other parts of the body. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …
Matched Products: … MAYZENT FILM-COATED TABLET 2MG ... MAYZENT FILM-COATED TABLET 0.25MG …
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and
Matched Mixtures name: … Cosyrel 5mg/5mg film-coated tablets ... Cosyrel 5mg/10mg film-coated tablets ... Cosyrel 10mg/5mg film-coated tablets …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Protease Inhibitors ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol …
Matched Products: … COVERSYL 5MG FILM-COATED TABLETS ... COVERSYL 10MG FILM-COATED TABLETS ... COVERSYL 5 MG FILM TABLET, 30 ADET …
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins
Nofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and ... adult patients with no prior antiretroviral treatment experience, further expanding the possibility and
Matched Mixtures name: … DELSTRIGO FILM COATED TABLET 100MG/300MG/300MG …
Matched Categories: … lamivudine, tenofovir disoproxil and doravirine …
Matched Products: … PIFELTRO FILM-COATED TABLET 100MG ... PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET …
Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. ... high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and ... Based on existing clinical data, Tolperisone is not sedating and does not interact with alcohol. …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … Netolp 50 mg Film Kaplı Tablet, 30 ADET ... Netolp 150 mg Film Kaplı Tablet, 30 ADET ... TOLKİMADO 50 MG FİLM KAPLI TABLET, 30 ADET …
Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Description: … Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable ... It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. ... [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … TUKYSA (TUCATINIB) FILM-COATED TABLETS 150 mg ... TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mg …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 10 TABLET ... DOLPHIN 250 MG FILM TABLET, 20 TABLET ... DOLPHIN 500 MG FILM TABLET, 10 TABLET …
Displaying drugs 1726 - 1750 of 1909 in total