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Displaying drugs 1901 - 1925 of 1960 in total

Roxithromycin

Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched International brands: … Ai Luo Xin ... Le Xi Qing …
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … ร็อกซิโทร - 100 ... ร๊อกซ์ลีคอน - 100 …

Cisapride

In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. The FDA issued a warning letter regarding this risk to health care professionals and patients.
Approved
Investigational
Withdrawn
Matched Description: … The FDA issued a warning letter regarding this risk to health care professionals and patients. …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … DISPEPRID 1 MG/ML ORAL SÜSPANSİYON, 100 ML …

Busulfan

Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Alcohols …
Matched Products: … MYLERAN 2 MG TABLET, 100 ADET …

Nizatidine

A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … AXID INYECTABLE 100 MG/4 ML …

Selegiline

A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Products: … MOVERDIN 5 MG TABLET, 100 ADET …

Methylene blue

Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and …
Matched Products: … BLUMET 100 MG/10 ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL ,1 AMPUL …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … beta-Quinine …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... [A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... Ophthalmological and Otological Preparations ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives …
Matched Products: … PREDNOL-L 20 MG LİYOFİLİZE ENJEKTABL AMPUL, 100 ADET ... PREDNOL-L 40 MG LİYOFİLİZE ENJEKTABL AMPUL, 100 ADET ... PREDNOL-L 250 MG LİYOFİLİZE ENJEKTABL AMPUL, 100 ADET …

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched International brands: … Dilacor-XR …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... into cardiac and vascular smooth muscle during depolarization. ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) ... Miscellaneous Calcium-channel Blocking Agents …
Matched Products: … HERBESSER CD 100 ... เฮอร์เบสเซอร์ อาร์ 100 ... Cartia XT …

Estriol

A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Description: … A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... Estriol is a major urinary estrogen. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … ESTRIOL VAJINAL KREM, 100 G …

Cocoa butter

Cocoa butter is an edible natural fat obtained from the Theobroma cocoa seeds that is predominantly found in dark chocolate . It is a rich source of monounsaturated and saturated fatty acids that mainly contains approximately 33% DB04224, 25% DB03796, and 33% DB03193 but does not contain caffeine or theobromine....
Approved
Matched Description: … (VLDL) cholesterol due to overproduction of large triglyceride-enriched VLDL cholesterol particles [ ... Cocoa butter is included in chocolate and other food products, and can also be found in over-the-counter ... It is a rich source of monounsaturated and saturated fatty acids [A33040] that mainly contains approximately …
Matched Mixtures name: … Up and Up Hemorrhoidal ... Avedana Hemorrhoidal …
Matched Categories: … Antipruritics and Local Anesthetics ... Diet, Food, and Nutrition …
Matched Products: … Suppo-H 1000mg/sup ... Suppo H Sup 1000mg …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … p-Bis(beta-chloroethyl)aminophenylalanine …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and ... and peripheral vasodilation in acute decongested heart failure. ... failure is underpinned by numerous physiological changes, including alteration in β-adrenergic signalling and …
Matched Products: … MULTİFLEKS KARDİYOMİL 20 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ …

Ciclopirox

Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Vaginal Creams, Foams, and Jellies …
Matched Products: … SEBİROX %1,5 ŞAMPUAN , 100 ML …

Zuclopenthixol

Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Description: … Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. ... It is an antagonist at D1 and D2 dopamine receptors. ... hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and …
Matched Products: … CLOPİXOL 10 MG FİLM KAPLI TABLET, 100 ADET …

Iodide I-131

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, ... Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its …
Matched Products: … MON.IYOT-131 74-18500 MBQ ORAL ÇÖZELTİ İÇEREN FLAKON, 100 MCİ ... MON.IYOT-131 0.37-7400 MBQ (10µ Cİ-200 M Cİ) ORAL KAPSÜL, 100 MCİ ... MON.IYOT-131 0.37-7400 MBQ (10µ Cİ-200 M Cİ) ORAL KAPSÜL, 100 MİCROCİ …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Description: … An anti-infective agent that is used topically to treat skin infections and orally for urinary tract …
Matched Mixtures name: … Sumadan Xlt ... BRUMETON 1 MG/ML+100 MG/ML GÖZ DAMLASI ... Sodium Sulfacetamide and Sulfur Aqueous Cleanser …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … SULFACETAMIDA SÓDICA 100 MG/ML …

Teicoplanin

Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine...
Approved
Investigational
Matched Description: … teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). ... All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation ... Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Teicoplanin Accord 100 mg Pulver zur Herstellung einer Injektionslösung ... Teicoplanin Mylan 100 mg Pulver zur Herstellung einer Injektions-/Infusionslösung oder einer Lösung zum ... Teicoplanin Sandoz 100 mg – Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …

Golimumab

Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Golimumab binds and inhibits soluble and transmembrane human TNFα. ... Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients ... Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMPONI 100MG FER ... SIMPONI 100MG ILO FER ... SIMPONI 100MG INJEKTOR …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … kinetic stability, partly due to its macrocyclic structure, and thus has a more favorable safety profile ... associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize ... DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and …
Matched Categories: … Alcohols ... Sugar Alcohols …
Matched Products: … DOTAREM INJECTION 27.932 g/ 100 ml …

Treprostinil

Treprostinil is a stable tricyclic analogue of prostacyclin that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.[L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.[L41855,L41860] The first agent approved for the treatment...
Approved
Investigational
Matched Description: … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room ... is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of pulmonary and ... systemic arterial vascular beds and the inhibition of platelet aggregation. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … TREPOKS 100 MG/20 ML İNFÜZYONLUK ÇÖZELTİ , 1 ADET …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. ... [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors. ... It is approved for use in Canada and other countries around the world, but not in the US. …
Matched Products: … Fluanxol Depot Inj 100mg/ml ... FLUANXOL DEPOT 10%100MG/ML ... FLUPENDURA DEPOT 100MG/ML …

Glipizide

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched International brands: … Zitrol XR …
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... [T28] Compared to the first-generation sulfonylureas, such as [tolbutamide] and [chlorpropamide], second-generation ... A179488] Compared to other members of the sulfonylurea drug group, glipizide displays rapid absorption and …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … MINIDIAB 5 MG 100 KOMRIME TABLET ... Glipizide XL ... Glucotrol XL …

Travoprost

Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … (Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)- …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …

(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE

Experimental
Matched Name: … (5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN …
Displaying drugs 1901 - 1925 of 1960 in total