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Displaying drugs 176 - 200 of 753 in total

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... influx through voltage-gated T-type calcium channels. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Beta blocking agents and calcium channel blockers …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth ... Nimodipine is a 1,4-dihydropyridine calcium channel blocker. ... It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Nisoldipine

Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth ... Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. ... It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Mixtures name: … Calcium With Vitamin D2 ... Calcium Chelate Plus Vit D ... SAFWA HEALTH CALCIUM AND VITAMIN D …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Mixtures name: … Pure Calcium calcium ... Calcium Plus ... Calcium Plus …
Matched Categories: … Calcium-Regulating Hormones and Agents ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential …

Potassium

Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … Potassium is an essential nutrient, like [Calcium] and [Magnesium]. …
Matched Mixtures name: … Isotonix Calcium Plus Formula ... Calcium and Magnesium 1:1 Plus Tablets ... Calcium & Magnesium Plus Potassium & Zinc …

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-sensing Receptor Agonist ... Increased Calcium-sensing Receptor Sensitivity …

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Mixtures name: … Calcium Plus ... Calcium Complex High Grade ... BNature Calcium Complex Tablets …

Isradipine

Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity...
Approved
Investigational
Matched Description: … Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into ... Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely ... It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

N-acetyltyrosine

N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Mixtures name: … Aminosyn II with Electrolytes in Dextrose with Calcium ... Aminosyn II with Electrolytes in Dextrose with Calcium ... Aminosyn II with Electrolytes in Dextrose with Calcium …

Nilvadipine

Nilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Approved
Investigational
Matched Description: … Nilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension. …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Human calcitonin

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Description: … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering ... constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus …
Matched Categories: … Calcium Homeostasis …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … [A234044] It plays an essential function in calcium homeostasis and bone metabolism. …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, ... heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced ... [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) ... Miscellaneous Calcium-channel Blocking Agents ... Selective Calcium Channel Blockers With Direct Cardiac Effects …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Mixtures name: … Drospirenone/Ethinyl Estradiol/Levomefolate Calcium and Levomefolate Calcium ... Drospirenone/ethinyl estradiol/levomefolate calcium and levomefolate calcium ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …

Indocyanine green acid form

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Description: … USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Mixtures name: … Calcium - Magnesium - Zinc Tab ... Calcium Magnesium Avec Vitamine D Et Zinc ... Citrate De Calcium Plus Vitamine D Et Zinc …

Hydrocortisone acetate

Approved
Vet approved

Gluconic Acid

Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Description: … Commonly found in salts with sodium and calcium. …

Edetic acid

A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Categories: … Calcium Chelating Agents ... Calcium Chelating Activity …

Lidoflazine

Approved
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Non-Selective Calcium Channel Blockers …

Iobenguane

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational

Parathyroid hormone

Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-Regulating Hormones and Agents …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium Acetylcysteine Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Displaying drugs 176 - 200 of 753 in total