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Displaying drugs 176 - 200 of 14591 in total

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... [T554] It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996. …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines …

Amitriptyline

Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline HCl …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …

LetibotulinumtoxinA

The aesthetic utility of botulinum toxin was discovered incidentally following its initial use in the treatment of facial spasmodic disorders in the early 1970s. The first aesthetic use of botulinum toxin was reported in 1989, when onabotulinumtoxinA (Botox) was used as a treatment for facial asymmetry resulting from iatrogenic facial...
Approved
Matched Description: … [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium ... [A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since ... LetibotulinumtoxinA has been a market-leading cosmetic product in South Korea for a number of years and …
Matched Categories: … Botulinum Toxins, Type A …

Ethynodiol diacetate

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Description: … synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and …
Matched Mixtures name: … Ethynodiol Diacetate and Ethinyl Estradiol ... Ethynodiol Diacetate and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Combination Contraceptives (with Estrogen and derivatives) …

Emtricitabine

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Description: … combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high risk adolescents and …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … tenofovir disoproxil and emtricitabine ... emtricitabine and tenofovir alafenamide ... Nucleic Acids, Nucleotides, and Nucleosides ... emtricitabine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and rilpivirine …

Methocarbamol

Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Description: … Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... [A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated ... in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts …
Matched Mixtures name: … Methocarbamol and Aspirin ... Muscle and Back Pain Relief ... Muscle and Back Pain Relief …

Trandolapril

Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and ... stable patients with left ventricular dysfunction, as an adjunct treatment for congestive heart failure, and …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … trandolapril and verapamil ... ACE Inhibitors and Calcium Channel Blockers …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early ... phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and ... of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and …
Matched Mixtures name: … Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride ... Trandolapril and Verapamil Hydrochloride …
Matched Categories: … Verapamil and analogues ... trandolapril and verapamil ... ACE Inhibitors and Calcium Channel Blockers …

Tromethamine

An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Matched Description: … cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used ... It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … , although their use is associated with increased toxicity through nonspecific targeting of wild-type ... Furthermore, osimertinib has been shown to spare wild-type EGFR during therapy, thereby reducing non-specific ... binding and limiting toxicity. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and ... Morphine is the most prevalent and principal alkaloid in opium, and it is responsible for most of the ... During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive. …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …
Matched Categories: … Alimentary Tract and Metabolism …

Colchicine

Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Description: … [L8192] Colchicine is used in the treatment of gout flares and Familial Mediterranean fever,[L8138] and ... [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602] …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … colchicine and probenecid …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … [L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol ... ,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and ... during the postpartum period, and this should be considered when assessing potential risks of hormonal …
Matched Mixtures name: … Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol ... Drospirenone and Ethinyl Estradiol …
Matched Categories: … drospirenone and estetrol ... drospirenone and estrogen ... drospirenone and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Collagenase clostridium histolyticum

Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Description: … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and ... [L14872] Also known as Qwo, this injection is the first approved injectable treatment for cellulite and …
Matched Categories: … Enzymes and Coenzymes ... Skin and Mucous Membrane Agents ... Preparations for Treatment of Wounds and Ulcers …

Belladonna

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Description: … Its roots, leaves and fruits contain [DB00424], [DB00747], and mostly, [DB00572]. ... Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... severe anticholinergic syndrome, which is associated with both central and peripheral manifestations …
Matched Mixtures name: … Belladonna and Opium ... Belladonna and Opium ... Belladonna and Opium …

Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Approved
Matched Mixtures name: … Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate ... Calcipotriene and Betamethasone Dipropionate …
Matched Categories: … Vitamin D and Analogues ... Skin and Mucous Membrane Agents …

Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and …
Matched Mixtures name: … Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide ... Hydralazine HCl and Hydrochlorothiazide …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Mixtures name: … Up and Up Antacid and Pain Relief ... Sodium Citrate and Citric Acid ... Effervescent Antacid and Pain Relief …
Matched Categories: … Alimentary Tract and Metabolism …

Vanadium

Approved
Experimental
Matched Mixtures name: … Chromium and Vanadium (combo) ... Revit Multi-vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Categories: … Diet, Food, and Nutrition …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant ... Selenium is an essential trace element and antioxidant. …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multivitamins and Minerals Tablets ... Golf Vitamin and Mineral Supplement …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Imipenem

Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Description: … gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. ... product with cilastatin and [relebactam] which was recently approved by the FDA. ... semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and …
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... caffeine and sodium benzoate ... sodium benzoate and sodium phenylacetate ... Various Alimentary Tract and Metabolism Products …

Esculin

Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Description: … naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and …

Flavin mononucleotide

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Description: … It is the principal form in which RIBOFLAVIN is found in cells and tissues. …
Matched Mixtures name: … Multi Vitamin and Fluoride ... Somarexin and C 1000 ... Multi Vitamin and Fluoride …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

Canis lupus familiaris dander

Canis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Dog Hair and Dander Canis spp ... Animal Allergens, Dog Hair and Dander Canis spp. ... Animal Allergens, Dog Hair and Dander Canis spp. …
Displaying drugs 176 - 200 of 14591 in total