Displaying drugs 2001 - 2025 of 2647 in total
2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide
Experimental
Matched Name: … 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide …
Matched Iupac: … 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide …
Matched Iupac: … 2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide …
N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE
Experimental
Matched Name: … N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE …
N-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE
Experimental
Matched Name: … N-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE …
N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide
Experimental
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … N-Lysinomethyltetracycline ... N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline ... N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- …
Matched Description: … It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. ... and [tetracycline]. ... Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and …
Matched Description: … It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. ... and [tetracycline]. ... Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and …
(6R)-Folinic acid
Experimental
Matched Synonyms: … L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl} …
Matched Categories: … Folic Acid and Derivatives …
Matched Categories: … Folic Acid and Derivatives …
Lotilaner
Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n- ... 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl …
Matched Iupac: … -5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl}formamido)-N- …
Matched Description: … L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Scabicides, Insecticides and Repellents …
Matched Iupac: … -5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl}formamido)-N- …
Matched Description: … L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and ... 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and …
Matched Categories: … Scabicides, Insecticides and Repellents …
IMT-288
IMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
Investigational
Matched Synonyms: … D-LYSINAMIDE, N-((4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODEC-1-YL)ACETYL)-D-TYROSYL-N6-(N ... -GLUTAMYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCY …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … p-N,N-bis(2-chloroethyl)amino-L-phenylalanine ... p-N-Bis(2-chloroethyl)amino-L-phenylalanine …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Certepetide
Investigational
Matched Synonyms: … Ac-Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys-NH2 cyclic (1→9)-disulfide ... L-Cysteinamide, N-acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl ... N-Acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl-L-cysteinamide, …
Enprofylline
Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Synonyms: … 3-n-propylxanthine …
Matched Description: … insufficiency, sickle cell disease, and diabetic neuropathy. ... Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular ... Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable …
Matched Description: … insufficiency, sickle cell disease, and diabetic neuropathy. ... Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular ... Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable …
NP-51
Investigational
Matched Synonyms: … 3-pyridinecarboximidamide, n-(2-hydroxy-3-(1-piperidinyl)propoxy)- …
Matched Name: … NP-51 …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Matched Name: … NP-51 …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Rineterkib
Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl ... Benzamide, 4-(3-amino-6-((1s,3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl …
Matched Iupac: … 4-{3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
Matched Iupac: … 4-{3-amino-6-[(1S,3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
Soquelitinib
Investigational
Matched Synonyms: … Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1 ... N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl …
N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA
Experimental
Matched Name: … N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA …
Ambroxol
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Synonyms: … N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol ... N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol …
Matched Description: … in providing protection against infection and irritating agents. ... It stimulates synthesis and release of surfactant by type II pneumocytes. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Mixtures name: … HISTIACIL NF ... TUSIGEN NF ... TUSIGEN NF …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … NEO BOROCILLINA FLUIDIFICANTE TOSSE …
Matched Description: … in providing protection against infection and irritating agents. ... It stimulates synthesis and release of surfactant by type II pneumocytes. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Mixtures name: … HISTIACIL NF ... TUSIGEN NF ... TUSIGEN NF …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … NEO BOROCILLINA FLUIDIFICANTE TOSSE …
TSN-084
Investigational
Matched Synonyms: … 3-PYRIDINECARBOXAMIDE, N-(3-FLUORO-4-((1-METHYL-6-(1H-PYRAZOL-4-YL)-1H-INDAZOL-5-YL)OXY)PHENYL)-1-(4- ... N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro …
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-2-oxo-6-( …
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-2-oxo-6-( …
Rezatapopt
Rezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Investigational
Matched Synonyms: … -methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl ... -methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methylbenzamide …
Cirtuvivint
Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor.
Investigational
Matched Synonyms: … 4-pyridinecarboxamide, 2-(4-methyl-1-piperazinyl)-n-(6-(1-methyl-1h-pyrazol-4-yl)-3-isoquinolinyl)- …
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl]-2-(4-methylpiperazin-1-yl)pyridine-4-carboxamide …
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl]-2-(4-methylpiperazin-1-yl)pyridine-4-carboxamide …
Fosclevudine alafenamide
Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection).
Investigational
Matched Synonyms: … L-alanine, n-((s)-hydroxyphenoxyphosphinyl)-, 1-methylethyl ester, 5'-ester with 1-(2-deoxy-2-fluoro- …
Matched Description: … Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and ... Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With …
Matched Description: … Fosclevudine alafenamide is under investigation in clinical trial NCT05238844 (A Study of Safety and ... Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With …
(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
Experimental
Matched Name: … (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE …
Matched Iupac: … 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Matched Iupac: … 4-methyl-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries ... In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries ... In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after …
Matched Categories: … Blood and Blood Forming Organs …
SPH-3127
SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(3-(3-((1R)-1-(CYCLOPROPYL((2R)-2-MORPHOLINYLCARBONYL)AMINO)ETHYL)-6-METHYL-1H-PYRAZOLO …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine
Experimental
Matched Name: … 6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide …
Displaying drugs 2001 - 2025 of 2647 in total