Displaying drugs 2076 - 2100 of 9094 in total
Fluocinonide
A topical glucocorticoid used in the treatment of eczema.
Approved
Investigational
Matched Iupac: … hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-8- …
Isotretinoin
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Iupac: … (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Desflurane
Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888]
Desflurane was granted...
Approved
Levoketoconazole
Cushing's syndrome (CS) is underpinned by chronic hypercortisolism leading to multisystem morbidity, including effects on the cardiovascular and endocrine systems, metabolic syndrome with accompanying changes in body composition, neuropsychiatric effects, changes in blood pressure and chemistry, and opportunistic infections.[A244078, A244083] Ketoconazole has been used both on- and off-label to treat...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl ... )piperazin-1-yl]ethan-1-one …
Matched Categories: … MATE 1 Inhibitors …
Matched Categories: … MATE 1 Inhibitors …
Moderna COVID-19 Vaccine
The Moderna COVID-19 Vaccine (mRNA-1273) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel coronavirus, SARS-CoV-2, leading...
Approved
Investigational
Matched Description: … NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .-1 protease inhibitor ... Alfa-1-antitripsina ... Alpha 1-antitrypsin …
Matched Name: … Alpha-1-proteinase inhibitor …
Matched Description: … Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor …
Matched Products: … PROLASTIN C 1000 MG IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Matched Name: … Alpha-1-proteinase inhibitor …
Matched Description: … Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor …
Matched Products: … PROLASTIN C 1000 MG IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Pipecuronium
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Approved
Matched Iupac: … 4-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-8-(4,4-dimethylpiperazin-4-ium-1-yl)-9a, ... 11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl]-1,1-dimethylpiperazin-1-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pancuronium
A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Approved
Matched Iupac: … 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(1-methylpiperidin-1-ium ... -1-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl]-1-methylpiperidin-1-ium …
Nickel sulfate
Nickel sulfate is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … Nickel sulfate(1:1) …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Synonyms: … 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Ganirelix
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Iupac: … (2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}-3-methylbutyl]-2 ... (2R)-6-{[bis(ethylamino)methylidene]amino}-N-[(1S)-1-{[(2S)-6-{[bis(ethylamino)methylidene]amino}-1-[ ... propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]hexanamide ... -[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-3-(4-chlorophenyl)-2-[(2R)-2-acetamido-3-(naphthalen-2-yl)propanamido] …
Matched Salts cas: … 129311-55-3 …
Matched Products: … ORGALUTRAN 0,25 MG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Matched Salts cas: … 129311-55-3 …
Matched Products: … ORGALUTRAN 0,25 MG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Pibrentasvir
Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Matched Iupac: … -5-yl}pyrrolidin-2-yl]-6-fluoro-1H-1,3-benzodiazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl]carbamate ... -{6-fluoro-2-[(2S)-1-[(2S,3R)-3-methoxy-2-[(methoxycarbonyl)amino]butanoyl]pyrrolidin-2-yl]-1H-1,3-benzodiazol ... methyl N-[(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5 …
Matched Description: … Mavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with ... therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C virus (HCV) genotypes 1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Mavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with ... therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C virus (HCV) genotypes 1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Iupac: … 5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Methyl salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Mixtures name: … Re-Lieved 3 in 1 Patch ... Med O-3 Bio- ... 701 Dieda Zhengtong Yaogao Medicated …
Ferrous sulfate anhydrous
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Synonyms: … iron sulfate (1:1) …
Matched Mixtures name: … Revival 1 Tab …
Matched Mixtures name: … Revival 1 Tab …
Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Dolutegravir
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration ... part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Mesoridazine
A phenothiazine antipsychotic with effects similar to chlorpromazine.
Approved
Investigational
Matched Synonyms: … 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine ... 10-(2(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine ... 2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine …
Matched Iupac: … 2-methanesulfinyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10H-phenothiazine …
Matched Salts cas: … 32672-69-8 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 2-methanesulfinyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10H-phenothiazine …
Matched Salts cas: … 32672-69-8 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Amantadine
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Synonyms: … 1-adamantanamine ... 1-adamantylamine ... 1-aminoadamantane …
Matched Iupac: … adamantan-1-amine …
Matched Salts cas: … 31377-23-8 …
Matched Mixtures name: … XL-3 VR …
Matched Iupac: … adamantan-1-amine …
Matched Salts cas: … 31377-23-8 …
Matched Mixtures name: … XL-3 VR …
Alipogene tiparvovec
Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers the Ser(447)X variant of the human lipoprotein lipase (LPL) gene. It is being investigated for the treatment of lipoprotein lipase (LPL) deficiency.[A259796, A259801, A259806, A259811]
Approved
Investigational
Matched Description: … Alipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers …
Gonadorelin
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
Approved
Investigational
Vet approved
Matched Iupac: … N-(1-{2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl}-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl)- ... 2-{2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol ... -3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamide …
Matched Salts cas: … 51952-41-1 …
Matched Products: … LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET …
Matched Salts cas: … 51952-41-1 …
Matched Products: … LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET …
Nafarelin
Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.
Approved
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl ... ]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-( ... ]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl …
Matched Description: … Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine …
Matched Description: … Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine …
Triptorelin
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl ... ]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-( ... ]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl ... 1H-indol-3-yl)propanamido]-4-methylpentanamide …
Matched Salts cas: … 124508-66-3 …
Matched Products: … GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DECAPEPTYL DEPOT 3,75 MG INJEKSIYONLUK SUSPANSIYON ICIN TOZ VE COZUCU, 1 ADET …
Matched Salts cas: … 124508-66-3 …
Matched Products: … GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... DECAPEPTYL DEPOT 3,75 MG INJEKSIYONLUK SUSPANSIYON ICIN TOZ VE COZUCU, 1 ADET …
Cycloserine
Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … (+)-4-amino-3-isoxazolidinone ... D-4-amino-3-isoxazolidone ... D-4-amino-3-isoxazolidinone …
Matched Iupac: … (4R)-4-amino-1,2-oxazolidin-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (4R)-4-amino-1,2-oxazolidin-3-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 2076 - 2100 of 9094 in total