Displaying drugs 2076 - 2100 of 3034 in total
Calcium lactate
Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide. Approved by the FDA as a direct food substance affirmed as generally recognized as safe, calcium lactate is...
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Hydroxypropanoic acid calcium salt …
Matched Description: … as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and ... It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide …
Matched Categories: … Alimentary Tract and Metabolism ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … as safe, calcium lactate is used as a firming agent, flavoring agent, leavening agent, stabilizer, and ... It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide …
Matched Categories: … Alimentary Tract and Metabolism ... Hydroxy Acids ... Carboxylic Acids …
APT-101
Investigational
Matched Synonyms: … Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Matched Iupac: … cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Matched Iupac: … cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Ritivixibat
Investigational
Matched Synonyms: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-1Lambda6,2,5-benzothiadiazepin-8-yl]oxy)propanoic acid …
Matched Iupac: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin-8-yl]oxy}propanoic acid …
Matched Iupac: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin-8-yl]oxy}propanoic acid …
Olanzapine
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H2 Antagonists …
Matched Products: … PROLANZ® 5 MG ... PROLANZ 10 MG ... PROLANZ ® 10MG …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H2 Antagonists …
Matched Products: … PROLANZ® 5 MG ... PROLANZ 10 MG ... PROLANZ ® 10MG …
FK352B
FK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.
Investigational
Matched Synonyms: … 2-((2R)-1-((2E)-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)PROP-2-ENOYL)PIPERIDIN-2-YL)ACETIC ACID ... 2-PIPERIDINEACETIC ACID, 1-((2E)-1-OXO-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-2-PROPEN-1-YL)-, (2R)- …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Stapokibart
Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
Investigational
Matched Synonyms: … Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal …
Inhibitor BEA388
Experimental
Matched Synonyms: … [5-(2-hydroxy-indan-1-ylcarbamoyl)-3,4-dihydroxy-2,5-[dibenzyl-oxy]-pentanoyl]-valinyl-amido-methane …
AVA-4746
Investigational
Matched Synonyms: … chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-(4-methylphenyl)propanoic acid ... Benzenepropanoic acid, .beta.-((((1-((2-chlorophenyl)methyl)-1,2-dihydro-4-hydroxy-5-methyl-2-oxo-3-pyridinyl …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … 1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl)pyridin-2-yl)benzoic acid ... Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin …
PF-06835919
PF-06835919 is under investigation in clinical trial NCT05463575 (Ketohexokinase Inhibition in NAFLD).
Investigational
Matched Synonyms: … -[(2S)-2-Methyl-1-azetidinyl]-6-(trifluoromethyl)-4-pyrimidinyl]-3-azabicyclo[3.1.0]hexane-6-acetic acid ... (2S)-2-METHYLAZETIDIN-1-YL)-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-YL)-3-AZABICYCLO(3.1.0)HEXAN-6-YL)ACETIC ACID …
Navafenterol
Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).
Investigational
Matched Synonyms: … 2-thiopheneacetic acid, .alpha. ... quinolinyl)ethyl)amino)methyl)-1h-benzotriazol-1-yl)propyl)(methyl)amino)cyclohexyl hydroxy(di-2-thienyl)acetate …
Matched Description: … Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and …
Matched Description: … Navafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and …
Pralmorelin
Investigational
Matched Synonyms: … D-alanyl-3-(2-naphthyl)-d-alanyl-l-alanyl-l-tryptophyl-d-phenylalanyl-l-lysinamide ... L-lysinamide, d-alanyl-3-(2-naphthalenyl)-d-alanyl-l-alanyl-l-tryptophyl-d-phenylalanyl- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Esuberaprost
Esuberaprost (GP-1681), a drug intended for participants with pulmonary arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and safety.
Investigational
Matched Synonyms: … Aps-314d free acid ... hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid ... 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4- …
Matched Iupac: … hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid …
Matched Description: … arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and …
Matched Iupac: … hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid …
Matched Description: … arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE
Experimental
Matched Name: … 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE …
Matched Iupac: … (2S)-1-(2-amino-4-chloro-5-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-(2-amino-4-chloro-5-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid …
Pagibaximab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI (STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID) (HUMAN MOUSE MONOCLONAL HU96 110 ... Immunoglobulin G1, anti-(Staphylococcus epidermidis lipoteichoic acid) (human-mouse monoclonal heavy ... IMMUNOGLOBULIN G1, ANTI-(STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID)(HUMAN-MOUSE MONOCLONAL HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE
Experimental
Matched Name: … (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE …
Matched Iupac: … 2-bromoethyl 2-(4-amino-2-formylphenyl)acetate …
Matched Iupac: … 2-bromoethyl 2-(4-amino-2-formylphenyl)acetate …
Rosoxacin
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Synonyms: … 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and ... Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and ... Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered …
Methylparaben
Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … p-Hydroxybenzoic acid methyl ester …
Matched Categories: … Increased Histamine Release ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Categories: … Increased Histamine Release ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Ropivacaine
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Synonyms: … L-N-n-propylpipecolic acid-2,6-xylidide …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Maplirpacept
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human …
Livmoniplimab
Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid
Experimental
Matched Synonyms: … 6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic acid …
Matched Name: … 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid …
Matched Iupac: … 4S)-2-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-3-acetamido-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Name: … 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid …
Matched Iupac: … 4S)-2-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-3-acetamido-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid …
Displaying drugs 2076 - 2100 of 3034 in total