Displaying drugs 2126 - 2150 of 2609 in total
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Methionine C-11
Investigational
Matched Synonyms: … 2-Amino-4-[11C]methylsulfanyl-butanoic acid, l-[S methyl[11C]methionine …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
BMS-986251
BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).
Investigational
Matched Synonyms: … PERFLUOROPROPAN-2-YL)-2,3,3A,4,5,9B-HEXAHYDRO-1H-BENZO(E)INDOLE-3-CARBONYL)-3-METHYLCYCLOHEXANE-1-CARBOXYLIC ACID …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
Ceftibuten
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … -(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid …
Matched Iupac: … amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and …
Matched Iupac: … amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and …
Vancomycin
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … }.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid …
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …
Camoteskimab
Camoteskimab is under investigation in clinical trial NCT06436183 (A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis).
Investigational
Matched Synonyms: … Immunoglobulin g1 (242-phenylalanine,243-glutamic acid,339-serine), anti-(human interleukin 18) (human …
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Synonyms: … Acidum mersalylicum …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Salts name: … Mersalyl sodium …
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... It is an outdated drug, and its approval has been discontinued by the FDA. ... Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. …
Matched Salts name: … Mersalyl sodium …
N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide
Experimental
Matched Synonyms: … (2S)-2-[3-[(2-bromoacetyl)amino]propanoylamino]-3-hydroxypropanoyl]amino]ethyl]anilino]-2-oxoacetic acid …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid …
Polyestradiol phosphate
Polymeric phosphoric acid ester of estradiol.
Approved
Matched Synonyms: … (17-beta)-Estra-1,3,5(10)-triene-3,17-diol polymer with phosphoric acid …
Matched Description: … Polymeric phosphoric acid ester of estradiol. …
Matched Categories: … Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Polymeric phosphoric acid ester of estradiol. …
Matched Categories: … Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
DOTMP SM-153
Investigational
Matched Synonyms: … 153sm-1,4,7,10-tetraazacyclododecane-1,4,7,10- tetramethylene-phosphonic acid …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Alrizomadlin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … -1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic acid ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' ... oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid …
Matched Iupac: … dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Matched Iupac: … dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Aklavine
Aklavine is under investigation in clinical trial NCT03026842 (Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With T(8;21)).
Investigational
Matched Synonyms: … 1-naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy …
Carisoprodol
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … carbamic acid 2-isopropylcarbamoyloxymethyl-2-methyl-pentyl ester ... (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and …
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Matched Categories: … Carboxylic Acids ... Carbamic Acid Esters …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and …
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Matched Categories: … Carboxylic Acids ... Carbamic Acid Esters …
BG-P400-TAT
Investigational
Matched Synonyms: … ethoxy}-ethoxy)-ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-acetic acid ... ]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]-3,5-diiodophenoxy]-3,5-diiodophenyl]acetic acid …
Matched Iupac: … 3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol-4-yl)methoxy]-3,5-diiodophenoxy}-3,5-diiodophenyl)acetic acid …
Matched Iupac: … 3,6,9,12,15,18-hexaoxaicosan-1-yl}-1H-1,2,3-triazol-4-yl)methoxy]-3,5-diiodophenoxy}-3,5-diiodophenyl)acetic acid …
N-Acetylmethionine
Experimental
Matched Synonyms: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Iupac: … (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
beta-D-glucose 6-phosphate
Experimental
Matched Synonyms: … beta-D-Glucose 6-phosphic acid …
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid …
Carbocisteine
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... by physicians in France and Italy. ... viruses and bacteria in thick bronchial mucus. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid …
Matched Description: … Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... by physicians in France and Italy. ... viruses and bacteria in thick bronchial mucus. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
INCB-086550
INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).
Investigational
Matched Synonyms: … 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN …
Bortezomib
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
Isoflurophate
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … Diisopropylfluorophosphoric acid ester …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Azlocillin
Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Synonyms: … oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Azlocillin sodium …
Matched Iupac: … oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts name: … Azlocillin sodium …
Symmetric dimethylarginine
Experimental
Matched Synonyms: … (S)-2-amino-5-(N',N''-dimethylguanidino)pentanoic acid …
Matched Iupac: … (2S)-2-amino-5-[(Z)-N',N''-dimethylcarbamimidamido]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Matched Iupac: … (2S)-2-amino-5-[(Z)-N',N''-dimethylcarbamimidamido]pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Displaying drugs 2126 - 2150 of 2609 in total