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Displaying drugs 2176 - 2200 of 2785 in total
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ... pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FLUCONAZOL ACIS 50MG ... FLUCONAZOL ACIS 150MG …
Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … Cyclic adenylic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester ... 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester …
Matched Description: … A5790] Because its chemical structure resembles that of the anesthetic agents in the para-amino-benzoic acid ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and
Matched Categories: … Cough and Cold Preparations …
Investigational
Matched Synonyms: … 1,3-benzenedisulfonic acid, 4-(((1,1-dimethylethyl)oxidoimino)methyl)- ... 4-(((1,1-dimethylethyl)oxidoimino)methyl)-1,3-benzenedisulfonic acid
Matched Categories: … Arylsulfonic Acids ... Sulfur Acids ... Sulfonic Acids
Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Description: … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated ... secondary hyperparathyroidism and resultant metabolic bone disease, hypocalcemia in patients undergoing ... reabsorption of calcium in the kidneys, and stimulating the release of calcium stores from the skeletal …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Bone Density Conservation Agents ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin D and Analogues …
Matched Products: … BONKY INJECTION ... BONKY SOFT CAPSULE …
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Name: … Lyme disease vaccine (recombinant OspA) …
Matched Description: … Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the ... Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi …
Experimental
Matched Name: … 3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 2-Amino-3-Oxo-4-Sulfo-Butyric Acid
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid
Experimental
Matched Name: … 3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid
Experimental
Matched Name: … 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid
Experimental
Matched Name: … 11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Matched Iupac: … 2-[2-(1H-indol-3-yl)acetamido]acetic acid
Experimental
Matched Name: … N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
Matched Iupac: … (2S)-2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid
Displaying drugs 2176 - 2200 of 2785 in total