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Displaying drugs 2201 - 2225 of 2769 in total

Oxaliplatin

Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Description: … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. ... refractory to an initial fluorouracil and leucovorin combination. ... [A260396] The DACH moiety also prevents cross-resistance with cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXITEL …

FG-2216

A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …

Fibroblast growth factor-1

Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ... pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Categories: … Sulfur Compounds …

Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Experimental
Matched Synonyms: … Cyclic adenylic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Tagetitoxin

Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …

Calcium glycerophosphate

Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … β-glycerophosphoric acid calcium salt …
Matched Description: … The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... phosphate levels and direct interaction with dental mineral [A27153]. ... nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings, and …
Matched Mixtures name: … Somarexin and C 1000 ... NUTROPLEX LIQUID WITH IRON AND LYSINE …

Cilofexor

Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …

Efzofitimod

Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …

Cerulenin

Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …

Magnesium phosphate

Experimental
Matched Synonyms: … Phosphoric acid, magnesium salt (2:3) …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids …

Deserpidine

Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Approved
Matched Synonyms: … (3β,16β,17α,18β,20α)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester …
Matched Description: … is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and ... antihypertensive properties that has been used for the control of high blood pressure and for the relief …
Matched Categories: … deserpidine and diuretics …

Ditiocarb zinc

Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Synonyms: … Diethyldithiocarbamic acid zinc salt …
Matched Description: … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and ... It also a dermatological sensitizer and allergen. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sulfur Compounds ... Acids, Acyclic ... Carboxylic Acids …

99mTc-HYNIC (Tyr3)-octreotide

Investigational
Matched Synonyms: … 99mtc-ethylenediamine n,n'-diacetic acid/hydrazinonicotinamide-tyr3-octreotide …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cefdinir

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Synonyms: … )-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … 4-yl)-2-(N-hydroxyimino)acetamido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and ... Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially …
Matched Categories: … Sulfur Compounds …

Erbumine

Investigational
Matched Synonyms: … -6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)-,4-piperidinecarboxylic acid ... 4-piperidinecarboxylic acid, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol …
Matched Iupac: … -({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid …

Efruxifermin

Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … fc fragment) fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid ... linker (ggggs)3 fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid …
Matched Description: … Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Ergometrine

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Synonyms: … D-lysergic acid-L-propanolamide ... D-lysergic acid 1-hydroxymethylethylamide ... (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl …
Matched Description: … An ergot alkaloid with uterine and vascular smooth muscle contractile properties. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones …

Erythromycin

Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and ... the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and ... Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin and Benzoyl Peroxide …
Matched Salts name: … Erythromycin sulfate …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … Spotex …

Hexaminolevulinate

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride …
Matched Description: … Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Keto Acids ... Carboxylic Acids ... Levulinic Acids …

Allisartan isoproxil

Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).
Investigational
Matched Synonyms: … 1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL …

Penicillamine

Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-2-amino-3-mercapto-3-methylbutanoic acid …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Matched Description: … It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Sulfur ... Antiinflammatory and Antirheumatic Products ... Penicillamine and Similar Agents ... Sulfur Compounds …

S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEPTANETHIOATE

Experimental
Matched Name: … S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEPTANETHIOATE …
Matched Iupac: … (2-{[2-(heptanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy]phosphinic acid …

Cangrelor

Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid …
Matched Iupac: … sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid …
Matched Description: … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
Displaying drugs 2201 - 2225 of 2769 in total