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Displaying drugs 201 - 225 of 12532 in total
Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … (3E)-3-phenylprop-2-enal ... (E)-3-Phenyl-2-propenal ... (E)-3-Phenylpropenal …
Matched Iupac: … (2E)-3-phenylprop-2-enal …
The N-acetyl derivative of glucosamine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … 2-Acetamido-2-deoxy-D-glucose …
Matched Iupac: … N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide …
Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47. It is a potent vasodilator with reported...
Approved
Investigational
Matched Synonyms: … (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen- ... (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS)­ 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H) ... PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)- …
Matched Iupac: … 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2- …
Matched Products: … İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL ... İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPUL ... VEBULIS 10 MCG/ML NEBÜLIZATÖR IÇIN ÇÖZELTI IÇEREN AMPUL,2 ML,30 ADET …
Approved
Matched Synonyms: … Iron(2+) L-ascorbate …
Matched Iupac: … 1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one ... lambda2-iron(2+) (2R)-2-[(1S)-1,2-dihydroxyethyl]-5-oxo-2,5-dihydrofuran-3,4-bis(olate) (5R)-5-[(1S)- …
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Description: … to be approved. indicated for managing diabetes mellitus type 2. ... Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... was originally approved by the FDA on Jan 08, 2014, to improve glycemic control in adults with type 2
Matched Salts cas: … 960404-48-2
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Synonyms: … N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide …
Matched Iupac: … N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide …
Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Synonyms: … 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine …
Matched Iupac: … (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] …
Matched Salts cas: … 153504-70-2
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Niacinamide 4% ... Adapalene 0.3% / Benzoyl Peroxide 2.5% / Niacinamide 4% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Niacinamide 4% …
Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc. Research suggests that clobetasol propionate demonstrates superior pharmacologic efficacy in the treatment of...
Approved
Investigational
Withdrawn
Matched Synonyms: … ,1':4,5]indeno[1,2-d][1,3]dioxol-2-one ... 4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2' …
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12R,13S)-8-(2-chloroacetyl)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Synonyms: … (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane ... L-erythro-2-(Methylamino)-1-phenylpropan-1-ol …
Matched Iupac: … (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol …
Matched Salts cas: … 1405-94-3
Matched Products: … Ephedrinhydrochlorid Aguettant 3 mg/ml Injektionslösung in Fertigspritze …
Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … (Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)- ... ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA. ... isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1- …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but …
Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Synonyms: … 2-Amino-3-methylbutyric acid ... (2S)-2-Amino-3-methylbutanoic acid …
Matched Iupac: … (2S)-2-amino-3-methylbutanoic acid …
Matched Mixtures name: … Bcaa 4% Inj ... AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML …
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Synonyms: … 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione …
Matched Iupac: … 6,9-bis[(2-aminoethyl)amino]-5H,10H-benzo[g]isoquinoline-5,10-dione …
Matched Description: … The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. ... It also inhibits doxorubicinol formation in human myocardium. [3] As a result, it is believed to be less ... It will compare pixantrone efficacy to that of gemcitabine. [2] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Iupac: … 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea …
Matched Products: … รีกิลา 3 ม.ก. ... REAGİLA 3 MG SERT KAPSÜL, 28 ADET ... REAGİLA 3 MG SERT KAPSÜL, 30 ADET …
Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Approved
Matched Synonyms: … (R)-N-2-Propynyl-1-indanamine ... (R)-indan-1-yl-prop-2-ynyl-amine …
Matched Iupac: … (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine …
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... VECTAVIR % 1 KREM, 2 G …
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … -2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one ... 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy …
Matched Iupac: … (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen …
Matched Description: … cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane ... N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamine …
Matched Iupac: … (3,3-diphenylpropyl)(1-phenylpropan-2-yl)amine …
Matched Salts cas: … 69-43-2
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of...
Approved
Investigational
Matched Synonyms: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Iupac: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Synonyms: … N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide …
Matched Iupac: … N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl] ... -3-carboxamide …
Approved
Matched Synonyms: … Monopotassium 2-hydroxypropanoate …
Matched Iupac: … potassium 2-hydroxypropanoate …
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Synonyms: … 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine ... trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine …
Matched Mixtures name: … Stelabid No 2
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Terfluzine-2 ... STILIZAN 2 MG KAPLI TABLET, 30 ADET …
Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Synonyms: … 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Synonyms: … N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine ... N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine …
Matched Iupac: … N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine …
Nelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), in both adult and pediatric patients whose disease has not responded to or has relapsed following at least two chemotherapy regimens. T-cell acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine …
Matched Iupac: … (2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Description: … [A2331,AA2334,2335] Results from 2 phase 2 studies on adult and pediatric T-ALL/T-LBL indicated that …
Displaying drugs 201 - 225 of 12532 in total