Displaying drugs 201 - 225 of 6258 in total
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Moab, chimeric, SGN-30, to CD30 antigen …
Matched Description: … [L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... multifocal leukoencephalopathy and death due to opportunistic JC virus infection post-treatment. ... Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Description: … [L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... multifocal leukoencephalopathy and death due to opportunistic JC virus infection post-treatment. ... Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Synonyms: … A F Green No.2 ... Green No. 2 ... Acid Green A …
Matched Iupac: … }cyclohexa-2,5-dien-1-ylidene]methyl]benzene-1-sulfonate ... disodium 4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)[(1Z,4Z)-4-{ethyl[(3-sulfophenyl)methyl]iminiumyl …
Matched Description: … solution which is widely used as a counterstain. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining ... It is used in histological applications and other labratory settings, and usually exists as a disodium …
Matched Iupac: … }cyclohexa-2,5-dien-1-ylidene]methyl]benzene-1-sulfonate ... disodium 4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)[(1Z,4Z)-4-{ethyl[(3-sulfophenyl)methyl]iminiumyl …
Matched Description: … solution which is widely used as a counterstain. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining ... It is used in histological applications and other labratory settings, and usually exists as a disodium …
Carbamazepine
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Synonyms: … 5-Carbamoyl-5H-dibenz(b,f)azepine ... 5-carbamoyl-5H-dibenz[b,f]azepine ... 5-Carbamoyl-5H-dibenzo(b,f)azepine …
Matched Iupac: … 2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaene-2-carboxamide …
Matched Description: … [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... UGT2B7 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … TEGRETOL 2% ... TEGRETOL ® 2% SUSPENSION ... Tegretol Oral Suspension 2% …
Matched Iupac: … 2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaene-2-carboxamide …
Matched Description: … [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... UGT2B7 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Products: … TEGRETOL 2% ... TEGRETOL ® 2% SUSPENSION ... Tegretol Oral Suspension 2% …
Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (propiolactone inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Epinastine
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Synonyms: … 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine …
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Description: … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells ... by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding ... to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Description: … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells ... by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding ... to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 3-Ring …
Favipiravir
Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775]
Not only does favipiravir inhibit...
Approved
Investigational
Matched Iupac: … 6-fluoro-3-hydroxypyrazine-2-carboxamide …
Matched Description: … [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... , Lassa virus, and now COVID-19. ... use in resistant cases of influenza. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... , Lassa virus, and now COVID-19. ... use in resistant cases of influenza. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-123':126-126')-BISDISULFIDE ... FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-123':126-126')-BISDISULPHIDE ... TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Influenza A virus A/Hong Kong/2671/2019 NIB-121 (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/2671/2019 NIB-121 (H3N2) antigen (UV, formaldehyde inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (UV, formaldehyde inactivated …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) ... Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803 …
Matched Description: … [A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , ... Nogapendekin alfa is a human IL-15N72D variant. ... a single inbakicept is complexed with two nogapendekin alfa components. …
Matched Categories: … Receptors, Interleukin-15 …
Matched Description: … [A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , ... Nogapendekin alfa is a human IL-15N72D variant. ... a single inbakicept is complexed with two nogapendekin alfa components. …
Matched Categories: … Receptors, Interleukin-15 …
Peramivir
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Iupac: … (1S,2S,3R,4R)-4-carbamimidamido-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic …
Matched Description: … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. ... Being an influenza virus neuraminidase inhibitor, peramivir works by preventing new viruses from emerging ... treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic …
Matched Description: … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. ... Being an influenza virus neuraminidase inhibitor, peramivir works by preventing new viruses from emerging ... treatment of acute uncomplicated influenza to pediatric patients 2 years and older who have been symptomatic …
Tretinoin
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched International brands: … Stieva-A …
Matched Synonyms: … Vitamin A acid ... all-trans-Vitamin A acid ... (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … A] (retinol). ... A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 ... [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. …
Matched Mixtures name: … Retisol-A ... Retisol-A ... Retisol-A …
Matched Categories: … Vitamin A …
Matched Products: … ESTERA 1 MG/G ... แอคซิน 2 ครีม ... Tretin-X …
Matched Synonyms: … Vitamin A acid ... all-trans-Vitamin A acid ... (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … A] (retinol). ... A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 ... [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. …
Matched Mixtures name: … Retisol-A ... Retisol-A ... Retisol-A …
Matched Categories: … Vitamin A …
Matched Products: … ESTERA 1 MG/G ... แอคซิน 2 ครีม ... Tretin-X …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". …
Acetaminophen
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched International brands: … Anacin-3 ... Dapa X-S …
Matched Synonyms: … N-acetyl-p-aminophenol …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Description: … FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent …
Matched Mixtures name: … A-FERİN PLUS 1 MG +15 MG+160 MG/5 ML PEDİYATRİK ŞURUP,100 ML ... Adventure Medical Kits 1-2 Person First Aid ... KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADET …
Matched Products: … İNFÜZYON İÇİN ÇÖZELTİ, 100 ML x 1 TORBA ... VIVIMED N GE FIE U KOPFSCH ... พาราแมน -2 …
Matched Synonyms: … N-acetyl-p-aminophenol …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Description: … FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent …
Matched Mixtures name: … A-FERİN PLUS 1 MG +15 MG+160 MG/5 ML PEDİYATRİK ŞURUP,100 ML ... Adventure Medical Kits 1-2 Person First Aid ... KATARİN 250 MG/100 MG/2 MG KAPSÜL, 15 ADET …
Matched Products: … İNFÜZYON İÇİN ÇÖZELTİ, 100 ML x 1 TORBA ... VIVIMED N GE FIE U KOPFSCH ... พาราแมน -2 …
Interferon beta-1a
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta 1-a …
Matched Products: … REBIF 44 MCG (12MIU) KULLANIMA HAZIR SIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... REBIF 22 MCG (6MIU) KULLANIMA HAZIR SIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Matched Products: … REBIF 44 MCG (12MIU) KULLANIMA HAZIR SIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... REBIF 22 MCG (6MIU) KULLANIMA HAZIR SIRINGADA ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Carboprost tromethamine
A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Approved
Matched Synonyms: … -5,13-dien-1-oate ... 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium (5Z,9α,11β,13E,15S)-9,11,15-trihydroxy-15-methylprosta ... 15(S)-15-methyl-PGF2α tromethamine salt …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl]hept-5-enoic ... acid; 2-amino-2-(hydroxymethyl)propane-1,3-diol …
Matched Description: … A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl]hept-5-enoic ... acid; 2-amino-2-(hydroxymethyl)propane-1,3-diol …
Matched Description: … A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy …
Paritaprevir
Paritaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo ... 1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide ... -2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[ …
Matched Iupac: … (1S,4R,6S,7Z,14S,18R)-N-(cyclopropanesulfonyl)-14-(5-methylpyrazine-2-amido)-2,15-dioxo-18-(phenanthridin …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... Protein 3 (NS3) and its activating cofactor Nonstructural Protein 4A (NS4A) are responsible for cleaving …
Matched Iupac: … (1S,4R,6S,7Z,14S,18R)-N-(cyclopropanesulfonyl)-14-(5-methylpyrazine-2-amido)-2,15-dioxo-18-(phenanthridin …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... Protein 3 (NS3) and its activating cofactor Nonstructural Protein 4A (NS4A) are responsible for cleaving …
Dosulepin
Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Synonyms: … (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine ... 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... Its hydrochloride form is a common active ingredient in different drug formulations. ... Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic …
Matched Salts cas: … 897-15-4 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... Its hydrochloride form is a common active ingredient in different drug formulations. ... Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic …
Matched Salts cas: … 897-15-4 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Oxcarbazepine
Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Synonyms: … 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide …
Matched Iupac: … 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide …
Matched Description: … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of ... its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood ... - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide …
Matched Description: … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of ... its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood ... - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Delamanid
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl ... (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies ... is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a ... In a clinical study involving patients with pulmonary multidrug-resistant tuberculosis or extensively …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies ... is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a ... In a clinical study involving patients with pulmonary multidrug-resistant tuberculosis or extensively …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA …
Matched Salts cas: … 130693-82-2 …
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... ARUDOR % 2 + % 0.5 GOZ DAMLASI, 5 ML …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE ... TRUVEX EYE DROPS 2% W/V …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA …
Matched Salts cas: … 130693-82-2 …
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... DORZASOPT GÖZ DAMLASI ,1 ŞIŞE ... ARUDOR % 2 + % 0.5 GOZ DAMLASI, 5 ML …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE ... TRUVEX EYE DROPS 2% W/V …
Influenza B virus B/Austria/1359417/2021 BVR-26 antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza B virus B/Austria/1359417/2021 BVR-26 antigen (UV, formaldehyde inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... of the virus) which results in an immunological defense against future exposure to the virus, or "antigen …
Matched Categories: … Inactivated Influenza B Virus Vaccine ... Influenza Vaccines …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... of the virus) which results in an immunological defense against future exposure to the virus, or "antigen …
Matched Categories: … Inactivated Influenza B Virus Vaccine ... Influenza Vaccines …
Dexpanthenol
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Synonyms: … (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide ... Provitamin B …
Matched Iupac: … (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide …
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... an essential component of a normally functioning epithelium. ... which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the …
Matched Mixtures name: … Mvc 9 Plus 3 Inj ... NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Aquasol A Cream …
Matched Categories: … Vitamin B Complex …
Matched Products: … Corneregel 50 mg Dexpanthenol pro 1 g Augengel ... PANTOMED 2 ML 500 MG AMPUL, 5 ADET ... PANTEBIOL 500 MG 2 ML AMPUL, 5 ADET …
Matched Iupac: … (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide …
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... an essential component of a normally functioning epithelium. ... which acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the …
Matched Mixtures name: … Mvc 9 Plus 3 Inj ... NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Aquasol A Cream …
Matched Categories: … Vitamin B Complex …
Matched Products: … Corneregel 50 mg Dexpanthenol pro 1 g Augengel ... PANTOMED 2 ML 500 MG AMPUL, 5 ADET ... PANTEBIOL 500 MG 2 ML AMPUL, 5 ADET …
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... It is the active descarboethoxy metabolite of loratidine (a second generation histamine). ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... It is the active descarboethoxy metabolite of loratidine (a second generation histamine). ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 201 - 225 of 6258 in total