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Displaying drugs 201 - 225 of 14438 in total

Eslicarbazepine acetate

Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Description: … stabilizing the inactivated state of voltage-gated sodium channels, thus preventing their return to ... Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and ... Eslicarbazepine acetate is marketed as Aptiom in North America and Zebinix or Exalief in Europe. …
Matched Categories: … Eslicarbazepine and prodrugs ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Eslicarbazepine

Eslicarbazepine is an anti-epileptic medication available commercially as eslicarbazepine acetate.
Approved
Matched Categories: … Eslicarbazepine and prodrugs ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Fluocinonide

A topical glucocorticoid used in the treatment of eczema.
Approved
Investigational
Matched Mixtures name: … Fluocinonide 0.05% / Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% …
Matched Categories: … fluocinonide and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Sulfoxone

Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.
Approved
Matched Salts name: … Sulfoxone sodium …
Matched Categories: … aldesulfone sodium …

Dipyrithione

Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available. It is currently used as a pesticide, and not used in any FDA approved drug products. Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which...
Approved
Matched Description: … [A32825] Pyrithione derivatives, such as [DB06815] and sodium pyrithione, are widely used as cosmetic ... [A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum ... preservatives and as anti-dandruff agents in shampoos. …

Butalbital

Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Description: … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. ... a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and ... It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety …
Matched Mixtures name: … Butalbital, Aspirin, and Caffeine ... Butalbital, Aspirin and Caffeine ... Butalbital, Aspirin, and Caffeine …
Matched Salts name: … Butalbital sodium …
Matched Categories: … Hypnotics and Sedatives …

Propafenone

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Categories: … Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Glipizide

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting …
Matched Mixtures name: … Glipizide and Metformin HCl ... Glipizide and Metformin HCl ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and …
Matched Mixtures name: … Lisinopril and HCTZ ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... lisinopril and diuretics ... lisinopril and amlodipine ... Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Description: … through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and …
Matched Mixtures name: … Glyburide and Metformin ... Glyburide and Metformin ... Glyburide and Metformin …
Matched Categories: … Alimentary Tract and Metabolism …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist …
Matched Mixtures name: … Buprenorphine and Naloxone ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Description: … agent, and is also recommended in certain diseases with incessant coughing. ... The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease …
Matched Mixtures name: … Acetaminophen And Codeine ... Acetaminophen And Codeine ... ACETAMINOPHEN AND CODEINe …
Matched Categories: … Cough and Cold Preparations ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives ... codeine and acetylsalicylic acid …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Categories: … Trimethoprim and Derivatives ... sulfamoxole and trimethoprim ... Sulfonamides and trimethoprim ... sulfametrole and trimethoprim ... sulfadiazine and trimethoprim …

Nystatin

Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species. It is one of the most effective antifungal agents synthesized by bacteria, in this case a strain of Streptomyces noursei, and is closely related to amphotericin...
Approved
Vet approved
Matched Description: … a number of yeasts and fungi, most notably _Candida_ species. ... Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against ... antifungal agents synthesized by bacteria, in this case a strain of _Streptomyces noursei_,[L10776] and …
Matched Mixtures name: … Nystatin and Triamcinolone ... Nystatin and Triamcinolone ... Nystatin and Triamcinolone …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Amphetamine

Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Description: … Amphetamine structure presents one chiral center and it exists in the form of dextro- and levo-isomers ... After being proven to reduce drug-induced anesthesia and produce arousal and insomnia, amphetamine racemic ... mix was registered by Smith, Kline and French in 1935. …
Matched Mixtures name: … Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine ... Dextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Plasma protein fraction (human)

The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … some electrolytes such as sodium, potassium and chloride. ... [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains ... protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Brompheniramine

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Up and Up Childrens Cold and Cough ... Dimetapp Cold and Cough and Nighttime Cold and Congestion ... Daytime Cold and Cough and NightTime Cold and Congestion Childrens …

Clidinium

Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Matched Mixtures name: … Chlordiazepoxide Hydrochloride and Clidinium Bromide ... Chlordiazepoxide HCl and Clidinium Bromide ... Chlordiazepoxide Hydrochloride and Clidinium Bromide …
Matched Categories: … Alimentary Tract and Metabolism ... clidinium and psycholeptics …

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line ... All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant[A176426]. ... Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Ophthalmological and Otological Preparations …

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Description: … alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide …
Matched Categories: … ramipril and bisoprolol ... bisoprolol and thiazides ... bisoprolol and amlodipine ... perindopril and bisoprolol ... Beta Blocking Agents and Thiazides …

Homatropine methylbromide

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Description: … It may also be used to prevent nausea, vomiting, and motion sickness. …
Matched Mixtures name: … Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... homatropine methylbromide and psycholeptics …

Ipratropium

Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide …

Levoleucovorin

Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, levoleucovorin and leucovorin are both used to counteract the toxic effects of folic …
Matched Categories: … sodium levofolinate ... Enzymes and Coenzymes ... Folic Acid and Derivatives …

Estriol

A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Description: … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the ... A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 201 - 225 of 14438 in total