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Displaying drugs 2276 - 2300 of 9508 in total
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Description: … [L35525] Stratagraft consists of two kinds of lab-grown skin cells, keratinocytes and dermal fibroblasts ... fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of ... which a patient's own skin is harvested and grafted onto the burn site - which has the disadvantage of
Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures in patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment. Human...
Approved
Matched Description: … of proliferation _in vitro_. ... and improved targeting of ethnic minorities increased pool of rare haplotypes [A32219]. ... Other advantages of HSC transplantation include a lower risk of transmitting infections by latent viruses …
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … The main function of albumin is to maintain the oncotic pressure of blood [A33706]. ... of US donors in FDA-licensed facilities in the US [F229]. ... of 585 amino acids organized in three repeated homolog domains (sites I, II, and III). …
Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. Dotatate gallium Ga-68 is used for a similar indication. Dotatate gallium Ga-68 has lower tumor uptake but this...
Approved
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Approved
Matched Description: … Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial …
Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike (S) protein, which is described to...
Approved
Investigational
Matched Description: … Bamlanivimab consists of two identical light chains of 214 amino acids and two identical heavy chains ... of 455 amino acids each; the Fc region is unmodified. ... Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Description: … Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. ... This defence includes the production of humoral immunity through the development of antibodies (through ... A seasonally-specific component of the influenza vaccine. …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. ... This defence includes the production of humoral immunity through the development of antibodies (through ... A seasonally-specific component of the influenza vaccine. …
Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated...
Approved
Investigational
Withdrawn
Matched Description: … Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase ... The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum...
Approved
Investigational
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory …
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Cycloguanil is the active metabolite of proguanil.
Approved
Matched Description: … Cycloguanil is the active metabolite of [proguanil]. …
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for in vivo diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures. It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in...
Approved
Matched Description: … It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. …
Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity. DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the preparation of the skin prior to surgery and to help reduce bacteria that can potentially cause skin infection....
Approved
Matched Description: … DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the preparation of ... defatting manifested by the following signs/symptoms; localized redness, itching, drying and cracking of
Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic thrombocytopenia .
Approved
Matched Description: … Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. ... Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic …
Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.
Approved
Matched Description: … Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting ... blood schizonticide specifically indicated for the treatment of chloroquine-resistant _Plasmodium falciparum …
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Description: … of excessive procoagulant responses to activating stimuli. ... Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine ... A lack of protein C in the body would lead to unchecked coagulation activation, resulting in thrombin …
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
CL-315555 is the C isomer of Verteporfin.
Approved
Matched Description: … CL-315555 is the C isomer of [Verteporfin]. …
CL-315585 is the D isomer of Verteporfin.
Approved
Matched Description: … CL-315585 is the D isomer of [Verteporfin]. …
Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Description: … [L10701] Recently, dexamethasone has been a drug of interest in the treatment of COVID-19. ... decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of ... In a June 16 2020 press release highlighting early results of a clinical trial, Randomized Evaluation …
Displaying drugs 2276 - 2300 of 9508 in total