Displaying drugs 2301 - 2325 of 2777 in total
Oxiconazole
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Synonyms: … 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime] …
Matched Description: … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin ... infections such as athlete's foot, jock itch and ringworm. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics …
Matched Description: … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin ... infections such as athlete's foot, jock itch and ringworm. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics …
Doxapram
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Salts name: … Doxapram hydrochloride …
Matched Products: … Doxapram Hydrochloride …
Matched Products: … Doxapram Hydrochloride …
CAN-106
CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.
Investigational
Matched Synonyms: … Immunoglobulin G [27-histidine,57-histidine,253-tyrosine,255- threonine,257-glutamic acid], anti-(human …
Tamsulosin
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Salts name: … Tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... tamsulosin and solifenacin ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Tamsulosin Hydrochloride ... Tamsulosin hydrochloride ... TAMSULOSIN HYDROCHLORIDE …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Salts name: … Tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... tamsulosin and solifenacin ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Tamsulosin Hydrochloride ... Tamsulosin hydrochloride ... TAMSULOSIN HYDROCHLORIDE …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY ... IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Salts name: … Idarubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Hydrochloride ... Idarubicin Hydrochloride Injection …
Matched Salts name: … Idarubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Hydrochloride ... Idarubicin Hydrochloride Injection …
Valaciclovir
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Salts name: … Valaciclovir hydrochloride ... Valaciclovir hydrochloride monohydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Amino Acids ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Valacyclovir Hydrochloride ... Valacyclovir hydrochloride ... VALACICLOVIR HYDROCHLORIDE …
Matched Salts name: … Valaciclovir hydrochloride ... Valaciclovir hydrochloride monohydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acyclovir and prodrug ... Nucleosides and Nucleotides ... Amino Acids ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Valacyclovir Hydrochloride ... Valacyclovir hydrochloride ... VALACICLOVIR HYDROCHLORIDE …
Trifluoperazine
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Description: … It is used as an antipsychotic and an antiemetic. …
Matched Salts name: … Trifluoperazine hydrochloride …
Matched Products: … Trifluoperazine Hydrochloride ... TRIFLUOPERAZINE HYDROCHLORIDE …
Matched Salts name: … Trifluoperazine hydrochloride …
Matched Products: … Trifluoperazine Hydrochloride ... TRIFLUOPERAZINE HYDROCHLORIDE …
Minocycline
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and …
Matched Salts name: … Minocycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Minocycline Hydrochloride ... Minocycline hydrochloride …
Matched Salts name: … Minocycline hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Minocycline Hydrochloride ... Minocycline hydrochloride …
Demeclocycline
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. …
Matched Salts name: … Demeclocycline hydrochloride …
Matched Products: … Demeclocycline Hydrochloride …
Matched Salts name: … Demeclocycline hydrochloride …
Matched Products: … Demeclocycline Hydrochloride …
Dextropropoxyphene
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. ... It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Propoxyphene Hydrochloride …
Matched Mixtures name: … Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen ... Propoxyphene Hydrochloride and Acetaminophen …
Matched Salts name: … Dextropropoxyphene hydrochloride …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Propoxyphene Hydrochloride …
Topiroxostat
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Xanthine oxidase inhibitors are classified into two groups; purine analogs such as...
Experimental
Matched Synonyms: … 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … ineffective in reducing uric acid levels under recommended dosing regimens. ... Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia ... Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … ineffective in reducing uric acid levels under recommended dosing regimens. ... Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia ... Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the …
Diclofenamide
A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 4,5-dichloro-benzene-1,3-disulfonic acid diamide …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … Thiazines …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … Thiazines …
4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
Experimental
Matched Name: … 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME …
Loxapine
An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Salts name: … Loxapine hydrochloride …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml …
Selegiline
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. ... A selective, irreversible inhibitor of Type B monoamine oxidase. …
Matched Salts name: … Selegiline hydrochloride …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase B Inhibitors …
Matched Products: … Selegiline Hydrochloride …
Matched Salts name: … Selegiline hydrochloride …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase B Inhibitors …
Matched Products: … Selegiline Hydrochloride …
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Description: … influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Beta blocking agents and calcium channel blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …
Matched Description: … influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Beta blocking agents and calcium channel blockers ... Calcium-Regulating Hormones and Agents ... ramipril and felodipine ... metoprolol and felodipine …
Carteolol
A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Matched Description: … beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and …
Matched Salts name: … Carteolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Carteolol Hydrochloride …
Matched Salts name: … Carteolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Carteolol Hydrochloride …
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Bendamustine
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bendamustine Hydrochloride ... Bendamustine Hydrochloride for Injection ... Bendamustine Hydrochloride Kabi 25mg Powder for Concentrate for Solution for Infusion …
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Bendamustine Hydrochloride ... Bendamustine Hydrochloride for Injection ... Bendamustine Hydrochloride Kabi 25mg Powder for Concentrate for Solution for Infusion …
Naftifine
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …
Matched Salts name: … Naftifine Hydrochloride …
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride …
Matched Salts name: … Naftifine Hydrochloride …
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride …
Ticlopidine
Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Iupac: … 5-[(2-chlorophenyl)methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine …
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride …
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride …
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and …
Matched Salts name: … Ethambutol hydrochloride …
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE …
Matched Salts name: … Ethambutol hydrochloride …
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE …
Displaying drugs 2301 - 2325 of 2777 in total