Displaying drugs 1 - 25 of 567 in total
Urea C-14
Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been linked...
Approved
Matched Synonyms: … 14C-urea ... Urea-14C ... Urea 14 C …
Matched Name: … Urea C-14 …
Matched Iupac: … (¹⁴C)urea …
Matched Description: … Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. ... The Urea Breath Test is based on the ability of the H. pylori enzyme urease to cleave urea into ammonia ... Radiolabelled urea is available in two forms as 13C and 14C. …
Matched Products: … HELITEST® CAPSULAS 37 KBQ UREA 14C ... PYtest ®(Carbon-14-Urea 1.0 microCurie Breath Test) …
Matched Name: … Urea C-14 …
Matched Iupac: … (¹⁴C)urea …
Matched Description: … Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. ... The Urea Breath Test is based on the ability of the H. pylori enzyme urease to cleave urea into ammonia ... Radiolabelled urea is available in two forms as 13C and 14C. …
Matched Products: … HELITEST® CAPSULAS 37 KBQ UREA 14C ... PYtest ®(Carbon-14-Urea 1.0 microCurie Breath Test) …
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Synonyms: … 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea ... N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Urea C-13
Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as Pranactin-Citric) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been...
Approved
Matched Synonyms: … 13C-urea ... (13C)urea ... Urea-13C …
Matched Name: … Urea C-13 …
Matched Iupac: … (13C)urea …
Matched Description: … Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. ... The Urea Breath Test is based on the ability of the H. pylori enzyme urease to cleave urea into ammonia ... Radiolabelled urea is available in two forms as 13C and 14C. …
Matched Categories: … 13C-urea …
Matched Products: … HELICOBACTER TEST INFAI- UREA 13 C …
Matched Name: … Urea C-13 …
Matched Iupac: … (13C)urea …
Matched Description: … Urea 13C is a urea molecule radiolabelled with the non-radioactive element carbon-13. ... The Urea Breath Test is based on the ability of the H. pylori enzyme urease to cleave urea into ammonia ... Radiolabelled urea is available in two forms as 13C and 14C. …
Matched Categories: … 13C-urea …
Matched Products: … HELICOBACTER TEST INFAI- UREA 13 C …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-Butyl-3-(p-methylphenylsulfonyl)urea ... N-Butyl-N'-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Chlormerodrin
Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Chlorpropamide
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-propyl-3-(p-chlorobenzenesulfonyl)urea ... n-propyl-N'-(p-chlorobenzenesulfonyl)urea …
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Tolazamide
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Gallium Ga-68 gozetotide
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Synonyms: … Gallium Ga 68-labeled psma ligand Glu-urea-Lys(ahx)-hbed-CC …
Carglumic acid
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Glycerol phenylbutyrate
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Approved
Matched Categories: … Urea Cycle Disorder Agents …
Acetohydroxamic acid
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Description: … It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary ... Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea …
Tacrolimus
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Pamidronic acid
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Apronalide
Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura .
Approved
Matched Iupac: … [2-(propan-2-yl)pent-4-enoyl]urea …
Benzoic acid
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability …
Matched Categories: … Urea Cycle Disorder Agents …
Matched Categories: … Urea Cycle Disorder Agents …
Hyaluronic acid
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Talbutal
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Gliquidone
Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Approved
Investigational
Matched Iupac: … -1-{4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonyl}urea …
Tivozanib
Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Iupac: … 1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea …
Ethotoin
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Displaying drugs 1 - 25 of 567 in total