Equilibrative nucleoside transporter 1

BE0001204ProteinHumansSLC29A1

Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed:10722669, PubMed:10755314, PubMed:12527552, PubMed:14759222, PubMed:15037197, PubMed:17379602, PubMed:21795683, PubMed:26406980, PubMed:27995448, PubMed:35790189, PubMed:8986748). It is acted on by 28 drugs in DrugBank.

Gene name
SLC29A1
UniProtKB entry
Q99808Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
456 residues · 50,219 Da
Also known as
ENT1 · Equilibrative NBMPR-sensitive nucleoside transporter · Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter · es nucleoside transporter · hENT1

Resolves to

Protein
UniProtQ99808UniProt nameS29A1_HUMAN
Gene
HGNCHGNC:11003NCBI Gene2030GenBank1845345GeneCardsSLC29A1
Pharmacology
IUPHAR/GtoPdb1117KEGGhsa:2030
Structure
PDB6OB6PDB6OB7PDB8TZI
Drugs

What you can answer from here — as of September 07, 2019

28DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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30GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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59+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Equilibrative nucleoside transporter 1, how selective are they, and which programs against it are still in active trials?

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