Steroid hormone receptor ERR1

BE0003722ProteinHumansESRRA

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It is acted on by 28 drugs in DrugBank.

Gene name
ESRRA
UniProtKB entry
P11474Swiss-Prot
Cellular location
Nucleus
Residues / weight
423 residues · 45,509 Da
Also known as
ERR-alpha · ERR1 · ESRL1 · Estrogen receptor-like 1 · Estrogen-related receptor alpha

Resolves to

Protein
UniProtP11474UniProt nameERR1_HUMAN
Gene
HGNCHGNC:3471NCBI Gene2101GenBank36609GeneCardsESRRA
Pharmacology
IUPHAR/GtoPdb622KEGGhsa:2101
Structure
PDB1XB7PDB2PJLPDB3D24
Drugs

What you can answer from here — as of September 07, 2019

28DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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48+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Steroid hormone receptor ERR1, how selective are they, and which programs against it are still in active trials?

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