Viral Fusion Protein Inhibitors

Viral Fusion Protein Inhibitors
Accession Number

Drugs that are designed to block the action of VIRAL FUSION PROTEINS and prevent VIRUSES from entering the cell.

DrugDrug Description
EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
LeronlimabA humanized monoclonal antibody being investigated
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
BMS-488043Investigated for use/treatment in HIV infection.
AplavirocInvestigated for use/treatment in HIV infection.
FostemsavirAn antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
Drugs & Drug Targets
EnfuvirtideEnvelope glycoproteintarget
EnfuvirtideCytochrome P450 2C19enzyme
EnfuvirtideCytochrome P450 2E1enzyme
LeronlimabC-C chemokine receptor type 5target
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme
BMS-488043Free fatty acid receptor 4target
AplavirocC-C chemokine receptor type 5target
FostemsavirCytochrome P450 3A4enzyme
FostemsavirUDP-glucuronosyltransferases (UGTs)enzyme
FostemsavirP-glycoprotein 1transporter
FostemsavirATP-binding cassette sub-family G member 2transporter
FostemsavirSolute carrier organic anion transporter family member 1B1transporter
FostemsavirSolute carrier organic anion transporter family member 1B3transporter
FostemsavirSerum albumincarrier
FostemsavirEnvelope glycoprotein gp160target