- Accession Number
Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
- ATC Classification
Drug Drug Description Pyrimethamine An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. Mefloquine An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax. Quinine An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. Amodiaquine An antimalarial drug. Primaquine An antimalarial indicated to prevent relapse of vivax malaria. Proguanil A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria. Halofantrine An antimalarial used for the treatment of severe malaria. Hydroxychloroquine An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus. Artemether An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. Lumefantrine An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. Artesunate Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. Artenimol For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941. Pyronaridine A benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin. Artemotil Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria... Atovaquone An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. Piperaquine For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Quinacrine For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Tafenoquine An antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria. Chlorproguanil Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide. Mizoribine Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. Artemisinin A medication indicated in the treatment of malaria. Dapsone A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. Chloroquine An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. Tetrandrine Not Annotated Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Cycloguanil Cycloguanil is the active metabolite of proguanil. Artefenomel Artefenomel has been investigated for the treatment of Malaria. JPC-3210 JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine...
- Drugs & Drug Targets