Serotonin 5-HT2C Receptor Antagonists

Name
Serotonin 5-HT2C Receptor Antagonists
Accession Number
DBCAT005169
Description

Entities that are capable of exerting an antagonistic effect on 5-HT2C receptors.

Drugs
DrugDrug Description
ZiprasidoneAn atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.
OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
PromazineA phenothiazine used to manage schizophrenia.
PropiomazinePropiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia.
MinaprineFor the treatment of depression
TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
MethysergideAn ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
SertindoleUsed in the treatment of schizophrenia.
MianserinFor the treatment of depression.
AsenapineAn atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.
AgomelatineAgomelatine is indicated to treat major depressive episodes in adults.
PaliperidoneAn atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
AripiprazoleAn atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
LoxapineA antipsychotic used for the treatment of schizophrenia.
CyproheptadineA serotonin and histamine antagonist used in the treatment of allergy symptoms and in combination with epinephrine in the treatment of anaphylaxis.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
ClomipramineA tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.
DoxepinA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
NefazodoneAn antidepressant used in the treatment of depression.
ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
AmoxapineA tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
NortriptylineA tricyclic antidepressant used in the treatment of depression.
TrimipramineA tricyclic antidepressant used to treat depression.
AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
CaptodiameCaptodiame is indicated for the treatment of anxiety.
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
LorpiprazoleIn 2016, lorpiprazole was classified in the "Chemical structure-related drug-like criteria of global approved drugs" as an antipsychotic and anxiolytic. An antipsychotic is a medication used to treat a state...
PizotifenA serotonin and tryptamine antagonist indicated for migraine prophylaxis.
CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
RisperidoneA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
Drugs & Drug Targets
DrugTargetType
ZiprasidoneAlpha-1A adrenergic receptortarget
ZiprasidoneDopamine D2 receptortarget
Ziprasidone5-hydroxytryptamine receptor 2Ctarget
ZiprasidoneDopamine D3 receptortarget
Ziprasidone5-hydroxytryptamine receptor 1Atarget
Ziprasidone5-hydroxytryptamine receptor 1Dtarget
ZiprasidoneHistamine H1 receptortarget
Ziprasidone5-hydroxytryptamine receptor 2Atarget
ZiprasidoneDopamine D4 receptortarget
Ziprasidone5-hydroxytryptamine receptor 7target
ZiprasidoneCytochrome P450 3A4enzyme
ZiprasidoneAlpha-2A adrenergic receptortarget
ZiprasidoneAlpha-1B adrenergic receptortarget
ZiprasidoneAlpha-2B adrenergic receptortarget
ZiprasidoneAlpha-2C adrenergic receptortarget
ZiprasidoneDopamine D1 receptortarget
ZiprasidoneDopamine D5 receptortarget
ZiprasidoneMuscarinic acetylcholine receptor M1target
ZiprasidoneMuscarinic acetylcholine receptor M2target
ZiprasidoneMuscarinic acetylcholine receptor M3target
ZiprasidoneMuscarinic acetylcholine receptor M4target
ZiprasidoneMuscarinic acetylcholine receptor M5target
Ziprasidone5-hydroxytryptamine receptor 1Btarget
Ziprasidone5-hydroxytryptamine receptor 1Etarget
Ziprasidone5-hydroxytryptamine receptor 6target
ZiprasidoneAldehyde oxidaseenzyme
ZiprasidoneSerum albumincarrier
ZiprasidoneP-glycoprotein 1transporter
ZiprasidoneAlpha-1-acid glycoprotein 1carrier
Ziprasidone5-hydroxytryptamine 3 receptortarget
Ziprasidone5-hydroxytryptamine receptor 5Atarget
OlanzapineDopamine D1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M1target
OlanzapineMuscarinic acetylcholine receptor M3target
Olanzapine5-hydroxytryptamine receptor 2Atarget
OlanzapineDopamine D4 receptortarget
OlanzapineHistamine H1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M4target
OlanzapineMuscarinic acetylcholine receptor M2target
OlanzapineDopamine D2 receptortarget
Olanzapine5-hydroxytryptamine receptor 2Ctarget
OlanzapineDopamine D3 receptortarget
OlanzapineAlpha-1B adrenergic receptortarget
OlanzapineCytochrome P450 1A2enzyme
Olanzapine5-hydroxytryptamine receptor 3Atarget
Olanzapine5-hydroxytryptamine receptor 6target
OlanzapineAlpha-1A adrenergic receptortarget
OlanzapineDopamine D5 receptortarget
OlanzapineSerum albumincarrier
OlanzapineAlpha-1-acid glycoprotein 1carrier
OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlanzapineCytochrome P450 2D6enzyme
OlanzapineP-glycoprotein 1transporter
OlanzapineCytochrome P450 2C19enzyme
OlanzapineD(1) dopamine receptortarget
OlanzapineBeta adrenergic receptortarget
Olanzapine5-hydroxytryptamine receptor 1target
OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
OlanzapineCytochrome P450 2C9enzyme
OlanzapineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineCytochrome P450 3A4enzyme
OlanzapineCytochrome P450 3A Subfamilyenzyme
Mirtazapine5-hydroxytryptamine receptor 2Atarget
Mirtazapine5HT3 serotonin receptortarget
MirtazapineAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Ctarget
MirtazapineKappa-type opioid receptortarget
MirtazapineHistamine H1 receptortarget
MirtazapineCytochrome P450 1A2enzyme
MirtazapineCytochrome P450 3A4enzyme
MirtazapineCytochrome P450 2D6enzyme
MirtazapineAlpha-1 adrenergic receptorstarget
MirtazapineSodium-dependent serotonin transportertransporter
PromazineDopamine D2 receptortarget
Promazine5-hydroxytryptamine receptor 2Atarget
Promazine5-hydroxytryptamine receptor 2Ctarget
PromazineAlpha-1A adrenergic receptortarget
PromazineMuscarinic acetylcholine receptor M1target
PromazineHistamine H1 receptortarget
PromazineCytochrome P450 2C19enzyme
PromazineCytochrome P450 1A2enzyme
PromazineCytochrome P450 3A4enzyme
PromazineCytochrome P450 2C9enzyme
PromazineCytochrome P450 2D6enzyme
Propiomazine5-hydroxytryptamine receptor 2Atarget
PropiomazineDopamine D2 receptortarget
PropiomazineHistamine H1 receptortarget
Propiomazine5-hydroxytryptamine receptor 2Ctarget
PropiomazineAlpha-1A adrenergic receptortarget
PropiomazineMuscarinic acetylcholine receptortarget
MinaprineDopamine D1 receptortarget
MinaprineDopamine D2 receptortarget
Minaprine5-hydroxytryptamine receptor 2Atarget
Minaprine5-hydroxytryptamine receptor 2Btarget
Minaprine5-hydroxytryptamine receptor 2Ctarget
MinaprineSodium-dependent serotonin transportertarget
MinaprineCytochrome P450 2D6enzyme
MinaprineMuscarinic acetylcholine receptor M1target
MinaprineAcetylcholinesterasetarget
MinaprineAmine oxidase [flavin-containing] Atarget
TramadolMu-type opioid receptortarget
TramadolSodium-dependent noradrenaline transportertarget
Tramadol5-hydroxytryptamine receptor 2Ctarget
TramadolKappa-type opioid receptortarget
TramadolSodium-dependent serotonin transportertarget
TramadolCytochrome P450 2D6enzyme
TramadolDelta-type opioid receptortarget
TramadolCytochrome P450 3A4enzyme
TramadolCytochrome P450 2B6enzyme
TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
TramadolMuscarinic acetylcholine receptor M3target
TramadolMuscarinic acetylcholine receptor M1target
TramadolUDP-glucuronosyltransferase 1-1enzyme
TramadolNeurokinin 1 receptortarget
TramadolSodium channel protein type 2 subunit alphatarget
TramadolTransient receptor potential cation channel subfamily V member 1target
TramadolNMDA receptortarget
TramadolAdenosine receptor A1target
TramadolAlpha-2 adrenergic receptorstarget
ClozapineDopamine D4 receptortarget
ClozapineHistamine H1 receptortarget
ClozapineDopamine D2 receptortarget
ClozapineNeuron-specific vesicular protein calcyontarget
ClozapineHistamine H4 receptortarget
Clozapine5-hydroxytryptamine receptor 2Atarget
Clozapine5-hydroxytryptamine receptor 1Atarget
Clozapine5-hydroxytryptamine receptor 2Ctarget
ClozapineDopamine D1 receptortarget
ClozapineCytochrome P450 1A2enzyme
ClozapineCytochrome P450 2D6enzyme
ClozapineDopamine D3 receptortarget
ClozapineMuscarinic acetylcholine receptor M1target
ClozapineMuscarinic acetylcholine receptor M2target
ClozapineMuscarinic acetylcholine receptor M3target
ClozapineMuscarinic acetylcholine receptor M4target
ClozapineMuscarinic acetylcholine receptor M5target
Clozapine5-hydroxytryptamine receptor 1Btarget
Clozapine5-hydroxytryptamine receptor 1Dtarget
Clozapine5-hydroxytryptamine receptor 1Etarget
Clozapine5-hydroxytryptamine receptor 3Atarget
Clozapine5-hydroxytryptamine receptor 6target
Clozapine5-hydroxytryptamine receptor 7target
ClozapineAlpha-1A adrenergic receptortarget
ClozapineAlpha-1B adrenergic receptortarget
ClozapineAlpha-2A adrenergic receptortarget
ClozapineAlpha-2B adrenergic receptortarget
ClozapineAlpha-2C adrenergic receptortarget
ClozapineCytochrome P450 2C9enzyme
ClozapineP-glycoprotein 1transporter
ClozapineCytochrome P450 3A4enzyme
ClozapineCytochrome P450 2C19enzyme
ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
ClozapineUDP-glucuronosyltransferase 1-4enzyme
ClozapineCytochrome P450 1A1enzyme
ClozapineCytochrome P450 2A6enzyme
ClozapineCytochrome P450 2C8enzyme
ClozapineGlutathione S-transferase Ptarget
Methysergide5-hydroxytryptamine receptor 2Atarget
Methysergide5-hydroxytryptamine receptor 1Atarget
Methysergide5-hydroxytryptamine receptor 7target
Methysergide5-hydroxytryptamine receptor 2Ctarget
Methysergide5-hydroxytryptamine receptor 2Btarget
Methysergide5-hydroxytryptamine receptor 1Btarget
Methysergide5-hydroxytryptamine receptor 1Ftarget
Methysergide5-hydroxytryptamine receptor 1Etarget
MethysergideCytochrome P450 3A4enzyme
Sertindole5-hydroxytryptamine receptor 2Atarget
Sertindole5-hydroxytryptamine receptor 2Ctarget
SertindoleDopamine D2 receptortarget
SertindoleAlpha-1A adrenergic receptortarget
SertindoleAlpha-1B adrenergic receptortarget
SertindoleAlpha-1D adrenergic receptortarget
SertindolePotassium voltage-gated channel subfamily H member 2target
Sertindole5-hydroxytryptamine receptor 6target
SertindoleCytochrome P450 2D6enzyme
SertindoleCytochrome P450 3A4enzyme
MianserinHistamine H1 receptortarget
MianserinAlpha-2A adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Atarget
Mianserin5-hydroxytryptamine receptor 2Ctarget
MianserinCytochrome P450 2D6enzyme
MianserinSodium-dependent serotonin transportertarget
MianserinCytochrome P450 3A4enzyme
MianserinCytochrome P450 1A2enzyme
MianserinCytochrome P450 2B6enzyme
MianserinSodium-dependent noradrenaline transportertarget
MianserinHistamine H4 receptortarget
Mianserin5-hydroxytryptamine receptor 1Atarget
MianserinAlpha-2C adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Btarget
Mianserin5-hydroxytryptamine receptor 1Ftarget
MianserinAlpha-2B adrenergic receptortarget
MianserinDopamine D3 receptortarget
MianserinKappa-type opioid receptortarget
MianserinSodium-dependent dopamine transportertarget
Mianserin5-hydroxytryptamine receptor 7target
MianserinDopamine D2 receptortarget
Mianserin5-hydroxytryptamine receptor 6target
MianserinAlpha-1 adrenergic receptorstarget
MianserinD(1) dopamine receptortarget
Asenapine5-hydroxytryptamine receptor 1Atarget
Asenapine5-hydroxytryptamine receptor 1Btarget
Asenapine5-hydroxytryptamine receptor 2Atarget
Asenapine5-hydroxytryptamine receptor 2Btarget
Asenapine5-hydroxytryptamine receptor 2Ctarget
Asenapine5-hydroxytryptamine receptor 6target
Asenapine5-hydroxytryptamine receptor 7target
AsenapineAlpha-2A adrenergic receptortarget
AsenapineAlpha-2B adrenergic receptortarget
AsenapineAlpha-2C adrenergic receptortarget
AsenapineAlpha-1A adrenergic receptortarget
AsenapineDopamine D1 receptortarget
AsenapineDopamine D2 receptortarget
AsenapineDopamine D3 receptortarget
AsenapineDopamine D4 receptortarget
AsenapineHistamine H1 receptortarget
AsenapineHistamine H2 receptortarget
AsenapineCytochrome P450 1A2enzyme
AsenapineCytochrome P450 2D6enzyme
Asenapine5-hydroxytryptamine receptor 5Atarget
AsenapineUDP-glucuronosyltransferase 1-4enzyme
AsenapineCytochrome P450 3A4enzyme
AsenapineBeta-1 adrenergic receptortarget
AsenapineBeta-2 adrenergic receptortarget
AsenapineSerum albumincarrier
Asenapinealpha1-acid glycoproteincarrier
Agomelatine5-hydroxytryptamine receptor 2Ctarget
AgomelatineMelatonin receptor type 1Btarget
AgomelatineMelatonin receptor type 1Atarget
AgomelatineCytochrome P450 2C9enzyme
AgomelatineCytochrome P450 1A2enzyme
PaliperidoneDopamine D2 receptortarget
Paliperidone5-hydroxytryptamine receptor 2Atarget
PaliperidoneHistamine H1 receptortarget
PaliperidoneAlpha-1A adrenergic receptortarget
PaliperidoneAlpha-1B adrenergic receptortarget
PaliperidoneDopamine D3 receptortarget
PaliperidoneDopamine D4 receptortarget
PaliperidoneDopamine D1 receptortarget
PaliperidoneAlpha-2A adrenergic receptortarget
PaliperidoneAlpha-2B adrenergic receptortarget
PaliperidoneAlpha-2C adrenergic receptortarget
Paliperidone5-hydroxytryptamine receptor 1Atarget
Paliperidone5-hydroxytryptamine receptor 1Dtarget
Paliperidone5-hydroxytryptamine receptor 2Ctarget
Paliperidone5-hydroxytryptamine receptor 7target
PaliperidoneCytochrome P450 3A4enzyme
PaliperidoneCytochrome P450 2D6enzyme
PaliperidoneCytochrome P450 3A5enzyme
PaliperidoneP-glycoprotein 1transporter
AripiprazoleDopamine D2 receptortarget
Aripiprazole5-hydroxytryptamine receptor 1Atarget
Aripiprazole5-hydroxytryptamine receptor 2Atarget
AripiprazoleCytochrome P450 3A4enzyme
AripiprazoleCytochrome P450 2D6enzyme
Aripiprazole5-hydroxytryptamine receptor 1Btarget
Aripiprazole5-hydroxytryptamine receptor 1Dtarget
Aripiprazole5-hydroxytryptamine receptor 1Etarget
AripiprazoleDopamine D1 receptortarget
AripiprazoleDopamine D5 receptortarget
AripiprazoleDopamine D3 receptortarget
AripiprazoleDopamine D4 receptortarget
Aripiprazole5-hydroxytryptamine receptor 2Ctarget
Aripiprazole5-hydroxytryptamine receptor 3Atarget
Aripiprazole5-hydroxytryptamine receptor 6target
Aripiprazole5-hydroxytryptamine receptor 7target
AripiprazoleHistamine H1 receptortarget
AripiprazoleAlpha-1A adrenergic receptortarget
AripiprazoleAlpha-1B adrenergic receptortarget
AripiprazoleAlpha-2A adrenergic receptortarget
AripiprazoleAlpha-2B adrenergic receptortarget
AripiprazoleAlpha-2C adrenergic receptortarget
AripiprazoleCytochrome P450 3A5enzyme
AripiprazoleCytochrome P450 3A7enzyme
AripiprazoleSerum albumincarrier
Aripiprazole5-hydroxytryptamine receptor 2Btarget
Aripiprazole5-hydroxytryptamine receptor 5Atarget
AripiprazoleBeta-1 adrenergic receptortarget
AripiprazoleBeta-2 adrenergic receptortarget
AripiprazoleHistamine H2 receptortarget
AripiprazoleHistamine H3 receptortarget
AripiprazoleHistamine H4 receptortarget
AripiprazoleMuscarinic acetylcholine receptor M1target
AripiprazoleMuscarinic acetylcholine receptor M2target
AripiprazoleMuscarinic acetylcholine receptor M3target
AripiprazoleMuscarinic acetylcholine receptor M4target
AripiprazoleMuscarinic acetylcholine receptor M5target
AripiprazoleKappa-type opioid receptortarget
AripiprazoleMu-type opioid receptortarget
AripiprazoleDelta-type opioid receptortarget
AripiprazoleGlutamate (NMDA) receptortarget
AripiprazoleSodium-dependent dopamine transportertarget
AripiprazoleSodium-dependent serotonin transportertarget
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
LoxapineDopamine D1 receptortarget
LoxapineDopamine D2 receptortarget
Loxapine5-hydroxytryptamine receptor 2Atarget
Loxapine5-hydroxytryptamine receptor 2Ctarget
Loxapine5-hydroxytryptamine receptor 1Atarget
Loxapine5-hydroxytryptamine receptor 1Btarget
Loxapine5-hydroxytryptamine receptor 1Dtarget
Loxapine5-hydroxytryptamine receptor 1Etarget
Loxapine5-hydroxytryptamine receptor 3Atarget
Loxapine5-hydroxytryptamine receptor 5Atarget
Loxapine5-hydroxytryptamine receptor 6target
Loxapine5-hydroxytryptamine receptor 7target
LoxapineAlpha-1A adrenergic receptortarget
LoxapineAlpha-1B adrenergic receptortarget
LoxapineAlpha-2A adrenergic receptortarget
LoxapineAlpha-2B adrenergic receptortarget
LoxapineAlpha-2C adrenergic receptortarget
LoxapineBeta-1 adrenergic receptortarget
LoxapineMuscarinic acetylcholine receptor M1target
LoxapineMuscarinic acetylcholine receptor M2target
LoxapineMuscarinic acetylcholine receptor M3target
LoxapineMuscarinic acetylcholine receptor M4target
LoxapineMuscarinic acetylcholine receptor M5target
LoxapineD(1) dopamine receptortarget
LoxapineDopamine D3 receptortarget
LoxapineDopamine D4 receptortarget
LoxapineDopamine D5 receptortarget
LoxapineHistamine H1 receptortarget
LoxapineHistamine H2 receptortarget
LoxapineHistamine H4 receptortarget
LoxapineSodium-dependent serotonin transportertarget
LoxapineSodium-dependent noradrenaline transportertarget
LoxapineSodium-dependent dopamine transportertarget
Cyproheptadine5-hydroxytryptamine receptor 2Atarget
CyproheptadineHistamine H1 receptortarget
CyproheptadineMuscarinic acetylcholine receptor M1target
CyproheptadineMuscarinic acetylcholine receptor M2target
CyproheptadineMuscarinic acetylcholine receptor M3target
Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
Cyproheptadine5-hydroxytryptamine receptor 7target
YohimbineAlpha-2A adrenergic receptortarget
YohimbineAlpha-2B adrenergic receptortarget
YohimbineAlpha-2C adrenergic receptortarget
Yohimbine5-hydroxytryptamine receptor 1Atarget
Yohimbine5-hydroxytryptamine receptor 1Btarget
Yohimbine5-hydroxytryptamine receptor 1Dtarget
YohimbineDopamine D2 receptortarget
YohimbineDopamine D3 receptortarget
Yohimbine5-hydroxytryptamine receptor 2Atarget
Yohimbine5-hydroxytryptamine receptor 2Ctarget
YohimbineCytochrome P450 2D6enzyme
YohimbineCytochrome P450 3A4enzyme
YohimbineATP-sensitive potassium channeltarget
Yohimbine5-hydroxytryptamine receptor 2Btarget
ClomipramineSodium-dependent serotonin transportertarget
ClomipramineSodium-dependent noradrenaline transportertarget
ClomipramineGlutathione S-transferase Ptarget
Clomipramine5-hydroxytryptamine receptor 2Atarget
ClomipramineCytochrome P450 1A2enzyme
ClomipramineCytochrome P450 2D6enzyme
ClomipramineCytochrome P450 2C19enzyme
ClomipramineP-glycoprotein 1transporter
ClomipramineCytochrome P450 3A4enzyme
Clomipramine5-hydroxytryptamine receptor 2Btarget
Clomipramine5-hydroxytryptamine receptor 2Ctarget
ClomipramineSerum albumincarrier
DoxepinSodium-dependent serotonin transportertarget
DoxepinSodium-dependent noradrenaline transportertarget
DoxepinHistamine H1 receptortarget
DoxepinHistamine H2 receptortarget
DoxepinCytochrome P450 2D6enzyme
DoxepinMuscarinic acetylcholine receptor M1target
DoxepinMuscarinic acetylcholine receptor M2target
DoxepinMuscarinic acetylcholine receptor M3target
DoxepinMuscarinic acetylcholine receptor M4target
DoxepinMuscarinic acetylcholine receptor M5target
DoxepinAlpha-1A adrenergic receptortarget
Doxepin5-hydroxytryptamine receptor 1Atarget
Doxepin5-hydroxytryptamine receptor 2Atarget
DoxepinCytochrome P450 2C19enzyme
DoxepinCytochrome P450 2C9enzyme
DoxepinCytochrome P450 1A2enzyme
DoxepinP-glycoprotein 1transporter
Doxepin5-hydroxytryptamine receptor 2Btarget
Doxepin5-hydroxytryptamine receptor 2Ctarget
DoxepinAlpha-1B adrenergic receptortarget
DoxepinAlpha-1D adrenergic receptortarget
DoxepinCytochrome P450 3A4enzyme
Doxepin5-hydroxytryptamine receptor 6target
DoxepinHistamine H4 receptortarget
DoxepinPotassium voltage-gated channel subfamily H member 2target
DoxepinSerum albumincarrier
DoxepinAlpha-1-acid glycoprotein 1carrier
Tegaserod5-hydroxytryptamine receptor 4target
Tegaserod5-hydroxytryptamine receptor 2Btarget
Tegaserod5-hydroxytryptamine receptor 2Ctarget
Tegaserod5-hydroxytryptamine receptor 2Atarget
TegaserodSodium-dependent serotonin transportertransporter
TegaserodCytochrome P450 1A2enzyme
TegaserodCytochrome P450 2C8enzyme
TegaserodCytochrome P450 2D6enzyme
TegaserodCytochrome P450 2E1enzyme
TegaserodATP-binding cassette sub-family G member 2transporter
TegaserodP-glycoprotein 1transporter
Nefazodone5-hydroxytryptamine receptor 2Atarget
NefazodoneSodium-dependent serotonin transportertarget
NefazodoneSodium-dependent noradrenaline transportertarget
NefazodoneAlpha-1A adrenergic receptortarget
NefazodoneAlpha-1B adrenergic receptortarget
NefazodoneCytochrome P450 3A4enzyme
NefazodoneCytochrome P450 2D6enzyme
NefazodoneSodium-dependent dopamine transportertarget
NefazodoneAlpha-2A adrenergic receptortarget
Nefazodone5-hydroxytryptamine receptor 1Atarget
NefazodoneCYP2B proteinenzyme
NefazodoneP-glycoprotein 1transporter
Nefazodone5-hydroxytryptamine receptor 2Ctarget
NefazodonePotassium voltage-gated channel subfamily H member 2target
NefazodoneCytochrome P450 3A Subfamilyenzyme
NefazodoneSolute carrier organic anion transporter family member 1B3transporter
NefazodoneSolute carrier organic anion transporter family member 2B1transporter
NefazodoneBile salt export pumptransporter
ImipramineSodium-dependent noradrenaline transportertarget
ImipramineSodium-dependent serotonin transportertarget
ImipramineCytochrome P450 1A2enzyme
ImipramineCytochrome P450 2C19enzyme
ImipramineCytochrome P450 2D6enzyme
ImipramineHistamine H1 receptortarget
ImipramineAlpha-1A adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 2Atarget
ImipramineMuscarinic acetylcholine receptor M1target
ImipramineMuscarinic acetylcholine receptor M2target
ImipramineMuscarinic acetylcholine receptor M3target
ImipramineMuscarinic acetylcholine receptor M4target
ImipramineMuscarinic acetylcholine receptor M5target
ImipraminePotassium voltage-gated channel subfamily D member 2target
ImipraminePotassium voltage-gated channel subfamily D member 3target
ImipramineAlpha-1D adrenergic receptortarget
ImipramineAlpha-1-acid glycoprotein 1carrier
ImipramineSolute carrier family 22 member 2transporter
ImipramineSolute carrier family 22 member 3transporter
ImipramineP-glycoprotein 1transporter
ImipramineSolute carrier family 22 member 4transporter
ImipramineCytochrome P450 3A4enzyme
ImipramineCytochrome P450 2B6enzyme
ImipramineCytochrome P450 2C18enzyme
ImipramineCytochrome P450 2E1enzyme
ImipramineCytochrome P450 3A7enzyme
Imipramine5-hydroxytryptamine receptor 2Ctarget
ImipramineAlpha-1B adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 7target
ImipramineD(1) dopamine receptortarget
ImipramineDopamine D2 receptortarget
ImipraminePotassium voltage-gated channel subfamily H member 2target
ImipramineSodium-dependent dopamine transportertarget
Imipramine5-hydroxytryptamine receptor 1Atarget
Imipramine5-hydroxytryptamine receptor 6target
ImipraminePotassium voltage-gated channel subfamily H member 1target
ImipramineSerum albumincarrier
ImipramineAlpha-1-acid glycoprotein 2target
AmoxapineSodium-dependent serotonin transportertarget
AmoxapineSodium-dependent noradrenaline transportertarget
AmoxapineAlpha-2A adrenergic receptortarget
AmoxapineDopamine D2 receptortarget
AmoxapineAlpha-1A adrenergic receptortarget
AmoxapineDopamine D1 receptortarget
AmoxapineMuscarinic acetylcholine receptor M1target
AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
AmoxapineAlpha-1-acid glycoprotein 1carrier
AmoxapineCytochrome P450 2D6enzyme
Amoxapine5-hydroxytryptamine receptor 2Atarget
Amoxapine5-hydroxytryptamine receptor 2Ctarget
Amoxapine5-hydroxytryptamine receptor 6target
Amoxapine5-hydroxytryptamine receptor 7target
AmoxapineDopamine D3 receptortarget
AmoxapineDopamine D4 receptortarget
AmoxapineHistamine H1 receptortarget
AmoxapineAlpha-1 adrenergic receptorstarget
AmoxapineMuscarinic acetylcholine receptortarget
Amoxapine5-hydroxytryptamine receptor 2Btarget
Amoxapine5-hydroxytryptamine receptor 3Atarget
Amoxapine5-hydroxytryptamine receptor 1Atarget
Amoxapine5-hydroxytryptamine receptor 1Btarget
AmoxapineAlpha-2 adrenergic receptorstarget
AmoxapineHistamine H4 receptortarget
AmoxapineGABA(A) Receptortarget
AmoxapineSodium-dependent dopamine transportertarget
NortriptylineSodium-dependent serotonin transportertarget
NortriptylineSodium-dependent noradrenaline transportertarget
NortriptylineCytochrome P450 1A2enzyme
NortriptylineCytochrome P450 2D6enzyme
NortriptylineSerum albumincarrier
NortriptylineAlpha-1-acid glycoprotein 1carrier
NortriptylineHistamine H1 receptortarget
Nortriptyline5-hydroxytryptamine receptor 2Atarget
NortriptylineAlpha-1A adrenergic receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Atarget
NortriptylineCytochrome P450 3A4enzyme
NortriptylineCytochrome P450 3A5enzyme
NortriptylineAlpha-1D adrenergic receptortarget
NortriptylineCytochrome P450 2C19enzyme
NortriptylineCytochrome P450 2E1enzyme
Nortriptyline5-hydroxytryptamine receptor 2Ctarget
NortriptylineAlpha-1B adrenergic receptortarget
NortriptylineAlpha-2 adrenergic receptorstarget
NortriptylineBeta adrenergic receptortarget
NortriptylineDopamine D2 receptortarget
NortriptylineSigma receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Ctarget
NortriptylineSodium-dependent noradrenaline transportertransporter
NortriptylineMuscarinic acetylcholine receptortarget
NortriptylineP-glycoprotein 1transporter
TrimipramineSodium-dependent serotonin transportertarget
TrimipramineSodium-dependent noradrenaline transportertarget
TrimipramineCytochrome P450 2D6enzyme
TrimipramineSodium-dependent dopamine transportertarget
Trimipramine5-hydroxytryptamine receptor 2Atarget
Trimipramine5-hydroxytryptamine receptor 1Atarget
TrimipramineAlpha-1A adrenergic receptortarget
TrimipramineAlpha-1B adrenergic receptortarget
TrimipramineDopamine D2 receptortarget
TrimipramineAlpha-2B adrenergic receptortarget
TrimipramineHistamine H1 receptortarget
TrimipramineCytochrome P450 2C19enzyme
TrimipramineP-glycoprotein 1transporter
TrimipramineCytochrome P450 2C9enzyme
Trimipramine5-hydroxytryptamine receptor 2Ctarget
Trimipramine5-hydroxytryptamine receptor 3Atarget
Trimipramine5-hydroxytryptamine receptor 1Dtarget
TrimipramineAlpha-2A adrenergic receptortarget
TrimipramineD(1) dopamine receptortarget
TrimipramineBeta adrenergic receptortarget
TrimipramineMuscarinic acetylcholine receptortarget
Trimipramine5-hydroxytryptamine receptor 1Ctarget
AmitriptylineSodium-dependent serotonin transportertarget
AmitriptylineSodium-dependent noradrenaline transportertarget
AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
AmitriptylineAlpha-2A adrenergic receptortarget
AmitriptylineCytochrome P450 1A2enzyme
AmitriptylineCytochrome P450 2C19enzyme
AmitriptylineCytochrome P450 2D6enzyme
AmitriptylineSerum albumincarrier
AmitriptylineAlpha-1-acid glycoprotein 1carrier
AmitriptylineHistamine H1 receptortarget
Amitriptyline5-hydroxytryptamine receptor 2Atarget
Amitriptyline5-hydroxytryptamine receptor 1Atarget
AmitriptylineAlpha-1A adrenergic receptortarget
AmitriptylineCytochrome P450 3A4enzyme
AmitriptylineCytochrome P450 3A5enzyme
AmitriptylinePotassium voltage-gated channel subfamily A member 1target
AmitriptylineAlpha-1D adrenergic receptortarget
AmitriptylineDelta-type opioid receptortarget
AmitriptylineKappa-type opioid receptortarget
AmitriptylineHigh affinity nerve growth factor receptortarget
AmitriptylineBDNF/NT-3 growth factors receptortarget
AmitriptylineCytochrome P450 2C9enzyme
AmitriptylineCytochrome P450 2B6enzyme
AmitriptylineCytochrome P450 2C8enzyme
AmitriptylineHistamine H2 receptortarget
AmitriptylineHistamine H4 receptortarget
AmitriptylineSigma non-opioid intracellular receptor 1target
Amitriptyline5-hydroxytryptamine receptor 2Ctarget
AmitriptylineAlpha-1B adrenergic receptortarget
Amitriptyline5-hydroxytryptamine receptor 7target
Amitriptyline5-hydroxytryptamine receptor 1Dtarget
AmitriptylineMu-type opioid receptortarget
Amitriptyline5-hydroxytryptamine receptor 1Btarget
Amitriptyline5-hydroxytryptamine receptor 6target
AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
Amitriptyline5-hydroxytryptamine receptor 1Ctarget
AmitriptylineMuscarinic acetylcholine receptortarget
AmitriptylineHERG human cardiac K+ channeltarget
AmitriptylineP-glycoprotein 1transporter
AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
Captodiame5-hydroxytryptamine receptor 2Ctarget
CaptodiameSigma non-opioid intracellular receptor 1target
CaptodiameDopamine D3 receptortarget
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
Lorpiprazole5-hydroxytryptamine receptor 2Atarget
Lorpiprazole5-hydroxytryptamine receptor 2Ctarget
LorpiprazoleAlpha-1 adrenergic receptorstarget
LorpiprazoleAlpha-2 adrenergic receptorstarget
LorpiprazoleHistamine H1 receptortarget
LorpiprazoleSodium-dependent serotonin transportertarget
LorpiprazoleCytochrome P450 2D6enzyme
LorpiprazoleCytochrome P450 3A4enzyme
LorpiprazoleSerum albumincarrier
PizotifenMuscarinic acetylcholine receptor M2target
PizotifenMuscarinic acetylcholine receptor M1target
PizotifenMuscarinic acetylcholine receptor M3target
Pizotifen5-hydroxytryptamine receptor 2Atarget
Pizotifen5-hydroxytryptamine receptor 2Btarget
Pizotifen5-hydroxytryptamine receptor 2Ctarget
PizotifenHistamine H1 receptortarget
Pizotifen5-hydroxytryptamine receptor 1Atarget
Pizotifen5-hydroxytryptamine receptor 1Btarget
Pizotifen5-hydroxytryptamine receptor 1Dtarget
PizotifenAlpha-1A adrenergic receptortarget
PizotifenAlpha-1B adrenergic receptortarget
PizotifenAlpha-1D adrenergic receptortarget
PizotifenAlpha-2A adrenergic receptortarget
PizotifenAlpha-2B adrenergic receptortarget
PizotifenAlpha-2C adrenergic receptortarget
PizotifenUDP-glucuronosyltransferase 2B10enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
CyclobenzaprineCytochrome P450 1A2enzyme
CyclobenzaprineCytochrome P450 3A4enzyme
CyclobenzaprineCytochrome P450 2D6enzyme
CyclobenzaprineSerum albumincarrier
CyclobenzaprineUDP-glucuronosyltransferase 1-4enzyme
CyclobenzaprineUDP-glucuronosyltransferase 2B10enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Btarget
Cyclobenzaprine5-hydroxytryptamine receptor 2Ctarget
Cyclobenzaprine5-hydroxytryptamine receptor 7target
Cyclobenzaprine5-hydroxytryptamine receptor 6target
CyclobenzaprineSodium-dependent serotonin transportertarget
CyclobenzaprineSodium-dependent noradrenaline transportertarget
CyclobenzaprineToll-like receptor 4target
CyclobenzaprineAldehyde oxidasetarget
RisperidoneCytochrome P450 2D6enzyme
RisperidoneCytochrome P450 3A4enzyme
RisperidoneP-glycoprotein 1transporter
RisperidoneSerum albumincarrier
RisperidoneAlpha-1-acid glycoprotein 1carrier
Risperidone5-hydroxytryptamine receptor 2Atarget
RisperidoneDopamine D2 receptortarget
RisperidoneAlpha-1B adrenergic receptortarget
RisperidoneAlpha-2B adrenergic receptortarget
RisperidoneAlpha-1A adrenergic receptortarget
RisperidoneAlpha-2C adrenergic receptortarget
RisperidoneHistamine H1 receptortarget
Risperidone5-hydroxytryptamine receptor 2Ctarget
Risperidone5-hydroxytryptamine receptor 1Dtarget
Risperidone5-hydroxytryptamine receptor 1Atarget
Risperidone5-hydroxytryptamine receptor 7target
RisperidoneD(2L) dopamine receptortarget
RisperidoneDopamine D1 receptortarget