Thyroid Gland Medullary Carcinoma (DBCOND0028790)

Identifiers

Synonyms
Thyroid Carcinoma, Medullary / Medullary carcinoma of thyroid / Thyroid Medullary Carcinoma / Thyroid Cancer, Medullary / Medullary Thyroid Carcinoma / Medullary Thyroid Cancer (MTC) / Medullary Thyroid Cancer / Parafollicular cell carcinoma (disorder) / Medullary carcinoma with amyloid stroma (morphologic abnormality) / Medullary thyroid carcinoma (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05534594
Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid CancerdiagnosticNot Availablerecruiting
NCT04759911
Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancertreatment2recruiting
NCT00134043
Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancertreatment2completed
NCT00068497
Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung CancertreatmentNot Availablecompleted
NCT02592356
Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancersupportive_careNot Availablecompleted
NCT00519896
Sunitinib Malate in Treating Patients With Iodine-Refractory Recurrent or Metastatic Thyroid Cancertreatment2completed
NCT00028496
Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancertreatment1completed
NCT01709435
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumorstreatment1completed
NCT00118248
Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancertreatment2completed
NCT00655655
Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT02293954
Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive CancerdiagnosticNot Availableactive_not_recruiting
NCT03892993
Patient Decision Aid in Supporting Decision-Making About When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients With Medullary Thyroid Cancer and Their CaregiversNo drug interventionssupportive_careNot Availablerecruiting
NCT01155258
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumorstreatment1completed
NCT00004074
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neutreatment1completed
NCT01204476
Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinomatreatment1completed
NCT02867592
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumorstreatment2active_not_recruiting
NCT05796960
European Multicenter Study on Surgical Management of Advanced Thyroid CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02088645
177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer.treatment1recruiting
NCT03630120
Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancertreatment2terminated
NCT02431715
18F-FDOPA PET in Neuroendocrine TumoursNo drug interventionsNot AvailableNot Availableno_longer_available
NCT03647657
177Lu-PP-F11N in Combination With Sacubitril for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancerbasic_science0completed
NCT04970134
Spanish Study for Molecular Characterization of Thyroid CarcinomaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00880503
Collection of Tissue Samples for Study of Multidrug ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT03636945
Evaluation of 18F-FDOPA PET-CT in the Preoperative Initial Assessment of Medullary Thyroid CarcinomaNo drug interventionsdiagnosticNot Availableunknown_status
NCT04787328
A Study of HA121-28 Tablets in Patients With Medullary Thyroid Carcinoma (MTC)No drug interventionstreatment2recruiting
NCT01511393
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01424878
Study of Molecular Pathways in Medullary Thyroid Carcinoma and Correlation of Molecular Data With Clinical Behavior of the MTC in Individuals PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01373736
123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine TumorsNo drug interventionsdiagnostic3unknown_status
NCT02586350
Study of Anlotinib in Patients With Medullary Thyroid Carcinoma(ALTER01031)treatment2 / 3completed
NCT01730638
ImmunoTEP for Patients With Medullary Thyroid Carcinoma.diagnostic1 / 2completed
NCT00923247
A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC)treatment1 / 2terminated
NCT06121271
Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed Indicationstreatment2not_yet_recruiting
NCT01736878
Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinomatreatment2withdrawn
NCT03246659
Radiolabelled CCK-2/Gastrin Receptor Analogue for Personalized Theranostic Strategy in Advanced MTCtreatment1completed
NCT06520319
Head-to-head Study of 68Ga-MGS5 Versus 68Ga-DOTATATE PET/CT in Patients With Medullary Thyroid Carcinomadiagnostic1recruiting
NCT06067594
Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma.No drug interventionsNot AvailableNot Availablecompleted
NCT00514046
Vandetanib to Treat Children and Adolescents With Medullary Thyroid Cancertreatment1 / 2completed
NCT03072160
Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancertreatment2completed
NCT01856920
QUILT-3.006 for Recurrent Medullary Thyroid Cancertreatment2completed
NCT01788982
Nintedanib(BIBF1120) in Thyroid Cancertreatment2completed
NCT01660984
Natural History Study of Children and Adults With Medullary Thyroid CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02174679
68Ga DOTATATE PET/CT in Neuroendocrine Tumors (Expanded Access)Not AvailableNot Availableno_longer_available
NCT02363647
Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon CancerNo drug interventionstreatmentNot Availableterminated
NCT02856347
Prospective Study Evaluating the Medullary Thyroid Cancer Management's Care Using PET F-DOPA in Patients With a High Level of Postoperative Residual ThyrocalcitoninNo drug interventionsdiagnosticNot Availablecompleted
NCT06292988
Predictive Factors for Medullary Thyroid Cancer AggressivenessNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01915485
Radiolabeled Molecules for Medullary Thyroid CancerNo drug interventionstreatment4unknown_status
NCT04211337
A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancertreatment3active_not_recruiting
NCT05830500
Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinomatreatment4recruiting
NCT04522570
Thermal Ablation of Cervical Metastases From Thyroid CarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT01757470
Vandetanib Risk Minimisation EffectivenessNo drug interventionsNot AvailableNot Availablecompleted
NCT06243965
Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma?No drug interventionsNot AvailableNot Availablecompleted
NCT06523582
Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04161391
Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or MutationsNo drug interventionstreatment1 / 2terminated
NCT02709889
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumorstreatment1 / 2terminated
NCT03899792
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumorstreatment1 / 2recruiting
NCT00582712
An Initial Study of Lithium in Patients With Medullary Thyroid Cancertreatment2terminated
NCT01683110
Expanded Access of Cabozantinib in Medullary Thyroid CancerNot AvailableNot Availableapproved_for_marketing
NCT03643055
18F-Fluorocholine PET/CT in Medullary Thyroid CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT01298323
Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatmenttreatment3active_not_recruiting
NCT05278364
Phase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid TumorNo drug interventionstreatment1 / 2recruiting
NCT01896479
A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancertreatment4active_not_recruiting
NCT05675605
A Study of TY-1091 in Patients With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT04204928
Pre-Approval Access Program (PAAP) for Pralsetinib (BLU-667) in Patients With Unresectable or Metastatic NSCLC or MTCNot AvailableNot Availableapproved_for_marketing
NCT03157128
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)treatment1 / 2recruiting
NCT04760171
Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal AmyloidosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04760288
A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC).treatment3withdrawn
NCT03037385
Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumorstreatment1 / 2completed
NCT01739634
The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancertreatment1 / 2unknown_status
NCT02465424
Assessing Quality of Life Tools in Medullary Thyroid Cancer PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01625520
SOM230 Alone or in Combination With RAD001 in Patients With Medullary Thyroid Cancertreatment2completed
NCT03906331
Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationNot AvailableNot Availableavailable
NCT06277180
68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTCNo drug interventionstreatmentNot Availablerecruiting
NCT03838692
Ponatinib in Advanced or Metastatic Medullary Thyroid Cancertreatment2withdrawn
NCT06141369
Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)No drug interventionstreatmentNot Availablerecruiting
NCT04280081
A Study of Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including RET Fusion-positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET Activationtreatment2active_not_recruiting
NCT01539655
Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of Vandetanibbasic_science1completed
NCT06079723
A Detailed Look At What Patients Experience In Medullary Thyroid Cancer Clinical StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting