Primitive Neuroectodermal Tumor (DBCOND0029801)

Identifiers

Synonyms

Primitive neuroectodermal tumour / Primitive Neuroectodermal Tumor (PNET) / Primitive Neuroectodermal Tumors (PNETs) / Primitive neuroectodermal tumor / Neuroectodermal Tumors, Primitive / Primitive neuroectodermal tumor (morphologic abnormality) / Primitive neuroectodermal tumor (disorder) / Neuroepithelioma (morphologic abnormality) / Supratentorial primitive neuroectodermal tumor (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03911388	HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors	G207	treatment	1	active_not_recruiting
NCT02624388	Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)	Genistein	supportive_care	2	terminated
NCT01661400	Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors	Cyclophosphamide Thalidomide	treatment	1	completed
NCT00180791	High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood	Carboplatin Cisplatin Etoposide Melphalan Thiotepa	treatment	2	unknown_status
NCT02094625	NAC to Prevent Cisplatin-induced Hearing Loss	Acetylcysteine	treatment	1	completed
NCT04541082	Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms	No drug interventions	treatment	1	recruiting
NCT02332889	Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs	Decitabine Hiltonol	treatment	1 / 2	terminated
NCT01222767	Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy	Zalypsis	treatment	2	completed
NCT06638931	Agnostic Therapy in Rare Solid Tumors	No drug interventions	treatment	2	recruiting
NCT00001209	A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors	Cyclophosphamide Doxorubicin Etoposide Ifosfamide Vincristine	treatment	1	completed
NCT00003515	Antineoplaston Therapy in Treating Patients With Metastatic, Recurrent, or Refractory Primitive Neuroectodermal Tumors	Antineoplaston A10	treatment	2	terminated
NCT01975116	p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors	Azurin-p28	treatment	1	completed
NCT03500991	HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors	No drug interventions	treatment	1	active_not_recruiting
NCT03434262	SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors	Filgrastim Gemcitabine Ribociclib Sonidegib Trametinib	treatment	1	completed
NCT03638167	EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors	No drug interventions	treatment	1	active_not_recruiting
NCT04521946	Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer	Antithymocyte immunoglobulin (rabbit) Beta-D-Glucose Etoposide Fludarabine Mechlorethamine Mycophenolate mofetil Tacrolimus Thiotepa Tromethamine	treatment	1	withdrawn
NCT04185038	Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors	No drug interventions	treatment	1	recruiting
NCT02508038	Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors	Zoledronic acid	treatment	1	recruiting
NCT00983398	Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors	Carboplatin Mannitol Mechlorethamine Thiosulfuric acid	treatment	1 / 2	unknown_status
NCT02162732	Molecular-Guided Therapy for Childhood Cancer	No drug interventions	treatment	Not Available	completed
NCT00563680	QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors	Ganitumab	treatment	2	completed