Peripheral Neuropathic Pain (DBCOND0049106)

Identifiers

Synonyms

Neuropathic Peripheral Pain / Peripheral pain / Peripheral neuropathic pain / Peripheral neuropathic pain (finding) / Neuralgia / Neuralgia (finding) / Neuralgia NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Gabapentin	An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.	Adenosine receptor A1target Voltage-dependent calcium channel subunit alpha-2/delta-1target Voltage-dependent calcium channel subunit alpha-2/delta-2target Branched-chain-amino-acid aminotransferase, cytosolicenzyme Large neutral amino acids transporter small subunit 1transporter Voltage-dependent N-type calcium channeltarget Potassium voltage-gated channel subfamily KQT member 3target Potassium voltage-gated channel subfamily KQT member 5target Gamma-aminobutyric acid type B receptor subunit 1target Gamma-aminobutyric acid type B receptor subunit 2target
Pregabalin	An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.	Excitatory amino acid transporter 3transporter Voltage-dependent calcium channel subunit alpha-2/delta-1target Large neutral amino acids transporter small subunit 1transporter

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01293851	Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage	No drug interventions	Not Available	Not Available	terminated
NCT05890053	To Evaluate the Long-term Safety and Efficacy of HSK16149 in Chinese Patients With Peripheral Neuralgia	Crisugabalin	treatment	3	active_not_recruiting
NCT04171453	Post-marketing Surveillance (PMS) to Observe the Safety and Effectiveness of Lyrica CR Extended Release Tablets	Pregabalin	Not Available	Not Available	unknown_status
NCT04431778	Evaluation of the Efficacy and Tolerance of Low Doses of Ethosuximide in the Treatment of Peripheral Neuropathic Pain	Ethosuximide	treatment	2	recruiting
NCT04494815	A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419	No drug interventions	treatment	1 / 2	completed
NCT02985216	Clinical Trial of YHD1119 in Patients With Peripheral Neuropathic Pain	Pregabalin	treatment	3	completed
NCT02209896	BlueWind Reprieve System for the Treatment of PNP	No drug interventions	treatment	Not Available	completed
NCT01240148	Determine the Effect of AZD3161,Injected Intradermally, on Quantitative Sensory Testing Variables in Normal and Ultraviolet-C (UVC) Exposed Skin in Healthy Volunteers	Lidocaine	basic_science	1	completed
NCT05416931	ACD440 Gel in Peripheral Neuropathic Pain	No drug interventions	treatment	2	completed
NCT05219812	A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain	No drug interventions	treatment	2	completed
NCT03009500	Randomized Controlled Trial of Efficacy and Safety of Local Anesthetics and Steroids for Chronic Peripheral Post-traumatic Neuropathic Pain	Bupivacaine Lidocaine Methylprednisolone Methylprednisone	diagnostic	3	completed
NCT03191136	Clinical Trial to Assess the Effect of Food on the Pharmacokinetics of YHD1119 in Healthy Volunteers	No drug interventions	treatment	1	completed
NCT06234917	Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning	No drug interventions	treatment	Not Available	completed
NCT01524796	NEP-TUNE: Neuropathic Pain - Treatment With Pregabalin Under Real-life Conditions in Denmark	No drug interventions	Not Available	Not Available	completed
NCT03733886	Burst Spinal Cord Stimulation for Neuropathic Pain.	No drug interventions	treatment	Not Available	completed
NCT01737294	Observation of the Use of QUTENZA™ in Standard Clinical Practice	Capsaicin	Not Available	Not Available	completed
NCT05817591	Response Profiles to High-concentration Capsaicin Desensitization in Patients With Peripheral Neuropathic Pain With or Without Allodynia: a Regional Multicenter Prospective Cohort	No drug interventions	Not Available	Not Available	recruiting
NCT02100046	Assessment of the Effectiveness of Ethosuximide in the Treatment of Peripheral Neuropathic Pain.	Ethosuximide	treatment	2	completed
NCT00221637	Efficacy of Valproate in Peripheral Neuropathic Pain	Valproic acid	treatment	2 / 3	terminated