Paragangliomas (DBCOND0051744)

Identifiers

Synonyms
Paraganglioma / Paraganglion neoplasm / Paraganglion neoplasm NOS / Neoplasm of paraganglion (disorder) / Gangliocytic paraganglioma (disorder) / Gangliocytic paraganglioma (morphologic abnormality) / Paraganglioma (morphologic abnormality) / Paraganglioma (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06427798
Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapytreatment1 / 2not_yet_recruiting
NCT02186678
Comparison of Diagnostic Performances of 68Ga-DOTATATE PET-CT and 18F-FDOPA PET-CT in Paragangliomas and Pheochromocytomas EvaluationNo drug interventionsdiagnosticNot Availablecompleted
NCT01347307
Stereotactic Body Radiotherapy for Spine TumorsNo drug interventionstreatmentNot Availablecompleted
NCT05636618
Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine TumorsNo drug interventionstreatment1 / 2recruiting
NCT06607692
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined with the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).treatment2recruiting
NCT02834013
Nivolumab and Ipilimumab in Treating Patients With Rare Tumorstreatment2active_not_recruiting
NCT06233903
18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous Systemdiagnostic2not_yet_recruiting
NCT03206060
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paragangliomatreatment2recruiting
NCT05142241
Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trialtreatment2suspended
NCT06573723
Institutional Registry of Rare DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01413503
A Phase II Study of 131I- Metaiodobenzylguanidine (MIBG) for Treatment of Metastatic or Unresectable Pheochromocytoma and Related TumorsNo drug interventionstreatment2completed
NCT01838187
Expanded Access Protocol Using 131I-MIBG Therapy +/- Vorinostat for Refractory Neuroblastoma, Pheochromocytoma, or ParagangliomaNot AvailableNot Availableno_longer_available
NCT06377033
Using the EHR to Advance Genomic Medicine Across a Diverse Health SystemNo drug interventionshealth_services_researchNot Availablerecruiting
NCT03839498
Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paragangliomatreatment2recruiting
NCT05082311
Cardiac and Vascular Changes in Pheochromocytoma and ParagangliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05418907
Exendin PET/CT for Imaging of ParagangliomasNo drug interventionsNot AvailableNot Availablerecruiting
NCT01022515
Specificity of Elevated Plasma EM66 Levels in PheochromocytomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01941849
Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and Paragangliomatreatment1withdrawn
NCT01373736
123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine TumorsNo drug interventionsdiagnostic3unknown_status
NCT00188019
Hereditary Paraganglioma: Evaluation of Screening Methods to Detect Tumors in SDH Positive CarriersNo drug interventionsdiagnosticNot Availablecompleted
NCT05451134
Predictors and Outcomes of Dysglycemia in Pheochromocytoma and ParagangliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04119024
Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumorstreatment1recruiting
NCT04573816
Development of a Tele-monitoring Program for Patients Undergoing Surgery for Pheochromocytoma and / or ParagangliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04711135
Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLstreatment2active_not_recruiting
NCT04605848
Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue (MICROBAT)No drug interventionsdiagnosticNot Availableterminated
NCT03160274
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated ConditionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04400474
Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Studytreatment2active_not_recruiting
NCT06523582
Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04788927
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03946527
LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)treatment2recruiting
NCT01560260
Linsitinib in Treating Patients With Gastrointestinal Stromal Tumorstreatment2completed
NCT00911729
Content Validation of Quality of Life and Symptom Questionnaires for Pheochromocytoma and ParagangliomaNo drug interventionsNot AvailableNot Availableterminated
NCT04081701
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.No drug interventionsdiagnostic4recruiting
NCT04187404
A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paragangliomatreatment1 / 2active_not_recruiting
NCT03165721
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancertreatment2terminated
NCT04276597
Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET.treatment2withdrawn
NCT03583528
DOTATOC PET/CT for Imaging NET PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03176693
Preoperative Alpha Blockade for Pheochromocytomatreatment3completed
NCT05233878
Prognostic's Factors of Head and Neck Paragangliomas EvolutionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06444607
Hereditary Pheochromocytoma Assessment of Tumour ImmunologiesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05883085
A Study on the Safety and Effectiveness of Anlotinib for Neoadjuvant Treatment of PPGLtreatment2recruiting
NCT02431715
18F-FDOPA PET in Neuroendocrine TumoursNo drug interventionsNot AvailableNot Availableno_longer_available
NCT00843037
Study Of Sunitinib In Patients With Recurrent Paraganglioma/Pheochromocytomatreatment2completed
NCT05948137
F-18 FDOPA PET/CT Versus I-123 MIBG Scintigraphy With SPECT/CT for the Diagnosis of Pheochromocytoma and ParagangliomaNo drug interventionsNot AvailableNot Availableterminated
NCT01377532
Compassionate Use of 131I-MIBG for Patients With Malignant PheochromocytomaNot AvailableNot Availableapproved_for_marketing
NCT00458952
Phase 1 Study of Iobenguane (MIBG) I 131 in Patients With Malignant Pheochromocytoma/Paragangliomatreatment1 / 2completed
NCT06155734
Fluorescence Guided Minimally-Invasive Resection Of Abdominal Paragangliomas Using Indocyanine GreenNot AvailableNot Availablerecruiting
NCT03344016
Multicenter Pheochromocytoma and Paraganglioma EvaluationNo drug interventionshealth_services_researchNot Availablerecruiting
NCT05885386
A Study on the Safety and Effectiveness of Temozolomide for Neoadjuvant Treatment of PPGLtreatment2recruiting
NCT06440122
The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)No drug interventionsNot AvailableNot Availablerecruiting
NCT03923257
Dosimetry Guided PRRT With 177Lu-DOTATATE in Children and Adolescentstreatment1 / 2withdrawn
NCT05069220
18F-MFBG PET/CT in the Evaluation of Neural Crest Tumordiagnostic0recruiting
NCT00339131
ULTRATRACE Iobenguane I 131 in Patients With Malignant Pheochromocytoma, Paraganglioma, or Metastatic Carcinoiddiagnostic1completed
NCT02177773
GA-68 DOTA-TOC of Somatostatin Positive Malignanciesdiagnostic1 / 2terminated
NCT01967576
Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paragangliomatreatment2completed
NCT01204476
Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinomatreatment1completed
NCT06045260
"Receptor Radionuclide Therapy With 177Lu-DOTATOCtreatment2recruiting
NCT01340794
Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or Paragangliomatreatment2terminated
NCT02961491
Expanded Access Program of Ultratrace Iobenguane I131 for Malignant Relapsed/Refractory Pheochromocytoma/ParagangliomaNot AvailableNot Availableapproved_for_marketing
NCT01590680
Expanded Access Protocol Using 131I-MIBGNo drug interventionsNot AvailableNot Availableavailable
NCT05702944
The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytomaprevention4recruiting
NCT05636540
In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and ParagangliomaNo drug interventionsdiagnostic0recruiting
NCT04017104
Dynamic Whole Body Positron Emission Tomography/Computed Tomography ImagingNo drug interventionsNot AvailableNot Availableunknown_status
NCT04891081
Plasma Metanephrines in Patients With Cyanotic and Acyanotic Congenital Heart DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT00874614
A Study Evaluating Ultratrace Iobenguane I131 in Patients With Malignant Relapsed/Refractory Pheochromocytoma/ParagangliomaNo drug interventionstreatment2unknown_status