Fatty Alcohols

Name
Fatty Alcohols
Accession Number
DBCAT000476
Description

Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Drugs
DrugDrug Description
VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
Sodium tetradecyl sulfateAn anionic surfactant used to treat varicose veins of the lower extremities.
Sodium lauryl sulfateAn anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent.
FarnesolA colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in...
2-ButanolNot Available
CyclohexanolMonohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem]
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
Dodecyl sulfateNot Available
VogliboseAn alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDNot Available
ChlorobutanolNo approved therapeutic indications on its own.
TanzisertibTanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
LomibuvirLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
MapracoratMapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis.
LifibrolLifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia.
Caprylic alcoholCaprylic alcohol has been used in trials studying the treatment of Essential Tremor.
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
AQX-1125AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
MethylpentynolNot Annotated
Caprylyl glycolNot Annotated
Isoamyl alcoholNot Available
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
1-Dodecanol1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary...
tert-butanolNot Available
IslatravirIslatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
MenthoneA medication used to treat stone formation in the gallbladder and liver.
Amyl acetateNot Annotated
AxomadolAxomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain).
Drugs & Drug Targets
DrugTargetType
VenlafaxineSodium-dependent serotonin transportertarget
VenlafaxineSodium-dependent noradrenaline transportertarget
VenlafaxineCytochrome P450 2D6enzyme
VenlafaxineCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent dopamine transportertarget
VenlafaxineP-glycoprotein 1transporter
VenlafaxineATP-binding cassette sub-family G member 2transporter
Sodium tetradecyl sulfateVitamin K-dependent protein Ctarget
Sodium tetradecyl sulfateVitamin K-dependent protein Starget
Sodium lauryl sulfateSerum albumincarrier
FarnesolAmine oxidase [flavin-containing] Btarget
FarnesolAmine oxidase [flavin-containing] Benzyme
FarnesolBile acid receptortarget
2-ButanolNADP-dependent isopropanol dehydrogenasetarget
CyclohexanolAlcohol dehydrogenase 1Btarget
Dodecyl sulfateLysozyme Ctarget
Dodecyl sulfateLipid A palmitoyltransferase PagPtarget
VogliboseMaltase-glucoamylase, intestinaltarget
DesvenlafaxineCytochrome P450 3A4enzyme
DesvenlafaxineSodium-dependent serotonin transportertarget
DesvenlafaxineSodium-dependent noradrenaline transportertarget
DesvenlafaxineCytochrome P450 2D6enzyme
DesvenlafaxineSodium-dependent dopamine transportertarget
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase subunit betatarget
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
ChlorobutanolPotassium voltage-gated channel subfamily H member 2target
Isoamyl alcoholRenintarget
LevomentholTransient receptor potential cation channel subfamily A member 1target
LevomentholTransient receptor potential cation channel subfamily M member 8target
LevomentholTransient receptor potential cation channel subfamily V member 3target
LevomentholKappa-type opioid receptortarget
LevomentholVoltage-dependent L-type calcium channeltarget
LevomentholCytochrome P450 3A4enzyme
1-DodecanolSDS hydrolase SdsA1target
1-DodecanolFatty-acid amide hydrolase 1target
tert-butanolRibonuclease pancreatictarget
tert-butanolTriosephosphate isomerasetarget
tert-butanolMethionine aminopeptidase 2target
tert-butanolBiphenyl-2,3-diol 1,2-dioxygenasetarget
tert-butanolCalmodulintarget