Fatty Alcohols

Fatty Alcohols
Accession Number

Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

DrugDrug Description
FarnesolA colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in...
DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
1-Dodecanol1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary...
Butyl alcoholNot Available
Sodium tetradecyl sulfateAn anionic surfactant used to treat varicose veins of the lower extremities.
Isoamyl alcoholNot Available
2-ButanolNot Available
MapracoratMapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis.
LifibrolLifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia.
MethylpentynolNot Annotated
Caprylyl glycolNot Annotated
Amyl acetateNot Annotated
SelgantolimodSelgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B).
Sodium lauryl sulfateAn anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent.
CyclohexanolMonohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem]
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
tert-butanolNot Available
Dodecyl sulfateNot Available
VogliboseAn alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
ChlorobutanolNo approved therapeutic indications on its own.
TanzisertibTanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
LomibuvirLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
Caprylic alcoholCaprylic alcohol has been used in trials studying the treatment of Essential Tremor.
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
AQX-1125AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
MentholNot Annotated
IslatravirIslatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
MenthoneA medication used to treat stone formation in the gallbladder and liver.
AxomadolAxomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain).
Drugs & Drug Targets
FarnesolAmine oxidase [flavin-containing] Btarget
FarnesolAmine oxidase [flavin-containing] Benzyme
FarnesolBile acid receptortarget
DesvenlafaxineCytochrome P450 3A4enzyme
DesvenlafaxineSodium-dependent serotonin transportertarget
DesvenlafaxineSodium-dependent noradrenaline transportertarget
DesvenlafaxineCytochrome P450 2D6enzyme
DesvenlafaxineSodium-dependent dopamine transportertarget
DesvenlafaxineUDP-glucuronosyltransferase 1-1enzyme
DesvenlafaxineUDP-glucuronosyltransferase 1-3enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B4enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B15enzyme
DesvenlafaxineUDP-glucuronosyltransferase 2B17enzyme
DesvenlafaxineCytochrome P450 2C19enzyme
1-DodecanolSDS hydrolase SdsA1target
1-DodecanolFatty-acid amide hydrolase 1target
Butyl alcoholHaloalkane dehalogenasetarget
Sodium tetradecyl sulfateVitamin K-dependent protein Ctarget
Sodium tetradecyl sulfateVitamin K-dependent protein Starget
Isoamyl alcoholRenintarget
2-ButanolNADP-dependent isopropanol dehydrogenasetarget
SelgantolimodToll-like receptor 8target
Sodium lauryl sulfateSerum albumincarrier
CyclohexanolAlcohol dehydrogenase 1Btarget
tert-butanolRibonuclease pancreatictarget
tert-butanolTriosephosphate isomerasetarget
tert-butanolMethionine aminopeptidase 2target
tert-butanolBiphenyl-2,3-diol 1,2-dioxygenasetarget
Dodecyl sulfateLysozyme Ctarget
Dodecyl sulfateLipid A palmitoyltransferase PagPtarget
VogliboseMaltase-glucoamylase, intestinaltarget
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase subunit betatarget
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
ChlorobutanolPotassium voltage-gated channel subfamily H member 2target
MentholTransient receptor potential cation channel subfamily M member 8target