Anti-Infective Agents, Urinary

Name
Anti-Infective Agents, Urinary
Accession Number
DBCAT000631  (DBCAT003690)
Description

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.

Drugs
DrugDrug Description
CycloserineA broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
TrimethoprimAn antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
FurazolidoneA drug for the treatment of infectious diarrhea.
SulfacetamideA corticosteroid used to treat inflammatory ocular conditions and acne vulgaris.
SulfametopyrazineAn antibiotic used in the treatment or prevention of bacterial infections and malaria.
NitrofurantoinAn antibiotic used to treat urinary tract infections.
LevofloxacinA fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
AmdinocillinUsed in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms.
OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
NitroxolineNitroxoline is an antibiotic agent.
PivmecillinamA prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs).
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
FinafloxacinFinafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
FurazidinNot Annotated
CarfecillinNot Annotated
Oxolinic acidNot Annotated
NifurtoinolNot Annotated
Piromidic acidNot Annotated
Pipemidic acidA quinolone antibiotic indicated in the treatment of susceptible urinary tract infections.
FosfomycinA broad spectrum antibiotic used to treat uncomplicated urinary tract infections.
FuraltadoneIndicated in combination with other drugs for the treatment of otitis media and externa.
Drugs & Drug Targets
DrugTargetType
CycloserineD-alanine--D-alanine ligase Atarget
CycloserineAlanine racemasetarget
CycloserineAromatic-L-amino-acid decarboxylaseenzyme
CycloserineProton-coupled amino acid transporter 2transporter
TrimethoprimDihydrofolate reductasetarget
TrimethoprimCytochrome P450 2C8enzyme
TrimethoprimCytochrome P450 3A4enzyme
TrimethoprimP-glycoprotein 1transporter
TrimethoprimCytochrome P450 2C9enzyme
TrimethoprimCytochrome P450 1A2enzyme
TrimethoprimMultidrug and toxin extrusion protein 1transporter
TrimethoprimMultidrug and toxin extrusion protein 2transporter
FurazolidoneDNAtarget
FurazolidoneAmine oxidase [flavin-containing] Benzyme
FurazolidoneAmine oxidase [flavin-containing] Aenzyme
SulfacetamideDihydropteroate synthasetarget
SulfacetamideDihydropteroate synthase type-1target
SulfacetamideFolic acid synthesis protein FOL1target
SulfametopyrazineDihydropteroate synthetasetarget
Nitrofurantoin30S ribosomal protein S10target
NitrofurantoinOxygen-insensitive NADPH nitroreductasetarget
NitrofurantoinProbable pyruvate-flavodoxin oxidoreductasetarget
NitrofurantoinATP-binding cassette sub-family G member 2transporter
NitrofurantoinNADPH--cytochrome P450 reductaseenzyme
NitrofurantoinBile salt export pumptransporter
NitrofurantoinP-glycoprotein 1transporter
NitrofurantoinCanalicular multispecific organic anion transporter 1transporter
LevofloxacinDNA gyrase subunit Atarget
LevofloxacinDNA topoisomerase 4 subunit Atarget
LevofloxacinCytochrome P450 1A2enzyme
LevofloxacinSolute carrier family 22 member 2transporter
LevofloxacinP-glycoprotein 1transporter
LevofloxacinSolute carrier family 22 member 4transporter
LevofloxacinMultidrug and toxin extrusion protein 1transporter
LevofloxacinMultidrug and toxin extrusion protein 2transporter
LevofloxacinCytochrome P450 2C9enzyme
LevofloxacinSerum albumincarrier
LevofloxacinSolute carrier organic anion transporter family member 4C1transporter
LevofloxacinSolute carrier family 22 member 1transporter
LevofloxacinSolute carrier organic anion transporter family member 1A2transporter
AmdinocillinPenicillin-binding protein 2target
AmdinocillinPenicillin-binding protein 2atarget
AmdinocillinPenicillin-binding protein 3target
AmdinocillinPenicillin-binding protein 1Atarget
AmdinocillinPenicillin-binding protein 2Btarget
AmdinocillinPenicillin-binding protein 1btarget
OfloxacinDNA gyrase subunit Atarget
OfloxacinDNA topoisomerase 4 subunit Atarget
OfloxacinDNA topoisomerase 2-alphatarget
OfloxacinCytochrome P450 1A2enzyme
OfloxacinSolute carrier family 22 member 5transporter
OfloxacinMultidrug resistance-associated protein 1transporter
OfloxacinSolute carrier family 22 member 6transporter
OfloxacinCanalicular multispecific organic anion transporter 1transporter
OfloxacinSolute carrier family 22 member 4transporter
OfloxacinBile salt export pumptransporter
SulfadoxineDihydropteroate synthetasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
NitroxolineMethionine aminopeptidase 2target
NitroxolineMagnesium cationtarget
NitroxolineManganese cationtarget
PivmecillinamPenicillin-binding protein 1Atarget
SulfameterDihydropteroate synthasetarget
FlumequineCytochrome P450 1A2enzyme
FinafloxacinDNA gyrase subunit Atarget
FinafloxacinDNA topoisomerase 4 subunit Atarget
FinafloxacinDNA topoisomerase 2-alphatarget
Pipemidic acidCytochrome P450 1A2enzyme
FosfomycinUDP-N-acetylglucosamine 1-carboxyvinyltransferasetarget