| Pantoprazole | A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. |
| Citalopram | A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. |
| Phenytoin | An anticonvulsant drug used in the prophylaxis and control of various types of seizures. |
| Omeprazole | A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. |
| Carisoprodol | A centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions. |
| Lansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Voriconazole | A triazole compound used to treat fungal infections. |
| Esomeprazole | A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. |
| Methylphenobarbital | For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. |
| Proguanil | A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria. |
| Phenobarbital | A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. |
| Fosphenytoin | An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. |
| Amitriptyline | A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. |
| Imipramine | A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. |
| Diazepam | A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. |
| Clomipramine | A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. |
| Clopidogrel | An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. |
| Cyclophosphamide | A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma. |
| Escitalopram | A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). |
| Thioridazine | A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. |
| Dexrabeprazole | Not Annotated |
| Rabeprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Lynestrenol | Lynestrenol has been used in trials studying the basic science of Transsexualism and Gender Dysphoria. |
| Etravirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Progesterone | A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. |
| Quinine | An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. |
| Ramelteon | A melatonin receptor agonist used to treat insomnia. |
| Tamoxifen | A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. |
| Zolpidem | A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. |
| Methadone | An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. |
| Dapsone | A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. |
| Acenocoumarol | An anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction. |
| Warfarin | A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. |
| Barbital | A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... |
| Hexobarbital | For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... |
| Pentobarbital | A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. |
| Primidone | An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. |
| Thiopental | A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. |
| Methsuximide | A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. |
| Vortioxetine | An atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). |
| Axitinib | An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. |
| Apixaban | An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. |
| Lapatinib | An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments. |
| (R)-warfarin | Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in... |
| (S)-Warfarin | Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in... |
| Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| Lacosamide | An antiepileptic drug used to treat partial onset seizures in adults. |
| Amiodarone | A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. |
| Trimethadione | An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. |
| Zonisamide | A sulfonamide anticonvulsant used to treat partial seizures. |
| Seratrodast | Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. |
| Artemether | An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. |
| Albendazole | A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. |
| St. John's Wort | An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. |
| Lorlatinib | An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. |
| Etizolam | Indicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia. |
| Praziquantel | An anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis. |
| Clobazam | A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. |
| Dexlansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Triclabendazole | An anthelmintic drug used to treat fascioliasis. |
| Esketamine | A NMDA receptor antagonist used for treatment-resistant depression. |
| Doxepin | A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. |
| Timolol | A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. |
| Doxazosin | An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. |
| Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| Nicotine | A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. |
| Perphenazine | A phenothiazine used to treat schizophrenia as well as nausea and vomiting. |
| Fedratinib | Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. |
| Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
| Estradiol | An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. |
| Bortezomib | A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
| Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
| Indomethacin | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. |
| Promazine | A phenothiazine used to manage schizophrenia. |
| Teniposide | A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. |
| Adinazolam | For the treatment of anxiety and status epilepticus. |
| Nilutamide | An antineoplastic hormone used to treat prostate cancer. |
| Pentamidine | An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. |
| Formoterol | An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. |
| Guanfacine | An alpha-2A adrenergic receptor agonist used to treat ADHD. |
| Sertraline | A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. |
| Tolbutamide | A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Cilostazol | An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. |
| Moclobemide | A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. |
| Arformoterol | A beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. |
| Flunitrazepam | For short-term treatment of severe insomnias, that are not responsive to other hypnotics. |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. |
| Loratadine | A second generation antihistamine used to manage the symptoms of allergic rhinitis. |
| Mephenytoin | A phenylhydantoin used to treat refractory partial epilepsy. |
| Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| Thalidomide | A medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum. |
| Aminophenazone | Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water. |
| Melatonin | An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. |
| Imatinib | A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. |
| Antipyrine | An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. |
| Trabectedin | An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma). |
| Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
| Terbinafine | An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. |
| Diphenhydramine | A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. |
| Propranolol | A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. |
| Ambrisentan | A selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications. |
| Ifosfamide | An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma. |
| Trimipramine | A tricyclic antidepressant used to treat depression. |
| Eletriptan | A triptan used for the treatment of migraines. |
| Clozapine | An antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. |
| Tolterodine | A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. |
| Lumiracoxib | For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults. |
| Sildenafil | A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. |
| Chlorpropamide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Gliclazide | A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Glyburide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
| Atomoxetine | A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD). |
| Bromazepam | A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. |
| Bupivacaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Cisapride | A medication used to treat heartburn associated with GERD. |
| Clomethiazole | Investigated for use/treatment in strokes. |
| Clotiazepam | For the treatment of anxiety disorders. |
| Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| Haloperidol | An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. |
| Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. |
| Ketobemidone | For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures. |
| Meperidine | An opioid agonist with analgesic and sedative properties used to manage severe pain. |
| Phenacetin | Used principally as an analgesic. |
| Propofol | A medication used in general anesthesia and for sedation. |
| Quazepam | A long -acting benzodiazepine used to manage insomnia. |
| Quetiapine | A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. |
| Selegiline | A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. |
| Testosterone | A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. |
| Valproic acid | An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. |
| Verapamil | A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. |
| Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
| Pipotiazine | An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients. |
| Almotriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Enfuvirtide | An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. |
| Oxiconazole | A topical antifungal used to treat a variety of dermatophyte infections. |
| Tapentadol | An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. |
| Prasugrel | A P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI. |
| Lorcaserin | A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. |
| Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
| Tofacitinib | A Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine. |
| Ospemifene | A non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. |
| Levomilnacipran | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD). |
| Macitentan | An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression. |
| Ixazomib | A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. |
| Romidepsin | A histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma. |
| Stiripentol | An anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome. |
| Brivaracetam | An anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain. |
| Rupatadine | A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis. |
| Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
| Testosterone cypionate | An androgen used to treat low or absent testosterone. |
| Testosterone enanthate | An androgen used to treat low or absent testosterone. |
| Testosterone undecanoate | An androgen used to treat low or absent testosterone. |
| Estradiol acetate | An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause. |
| Estradiol benzoate | Estradiol benzoate is not currently available in any FDA or Health Canada approved products. |
| Estradiol cypionate | An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. |
| Estradiol dienanthate | Estradiol dienanthate is not currently available in any FDA or Health Canada approved products. |
| Estradiol valerate | An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. |
| Piperaquine | For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638. |
| Asunaprevir | An NS3 protease inhibitor used to treat hepatitis C genotype 1b. |
| Nabiximols | In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have... |
| Medical Cannabis | The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical... |
| Bioallethrin | Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. |
| Lofexidine | A centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults. |
| Labetalol | An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. |
| Binimetinib | A medication used to treat metastatic melanoma with specific mutations. |
| Encorafenib | A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations. |
| Dexibuprofen | For more information, refer to ibuprofen. |
| Vilazodone | An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. |
| Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
| Lovastatin | An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. |
| Hydrocodone | An opioid agonist used as an analgesic and antitussive agent. |
| Nebivolol | A beta blocking agent used to treat hypertension and aid in the management of heart failure. |
| Capravirine | Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. |
| Voxelotor | A drug used to inhibit the polymerization of hemoglobin S, preventing the painful and sometimes lethal vaso-occlusive crises associated with sickle cell disease. |
| Norethisterone | A synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis. |
| Cenobamate | A small molecule drug indicated to treat partial onset seizures in adults. |
| Selumetinib | A MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN). |
| Fenfluramine | Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. |
| Oliceridine | A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists. |
| Lonafarnib | A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies. |
| Pirfenidone | An agent used for the treatment of idiopathic pulmonary fibrosis (IPF). |
| Oxymetazoline | An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. |
| Ticlopidine | A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). |
| Methylene blue | An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia. |