- Accession Number
Derivatives of ethylamine (the structural formula CH3CH2NH2).
Drug Drug Description Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. Sapropterin A cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). Fenfluramine Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. Methoxamine An alpha adrenergic agonist used to treat hypotension. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Cysteamine A cystine depleting agent used to treat the effects of cystinosis. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. Ritodrine An adrenergic beta agonist used to treat premature labor. Phenoxybenzamine An alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating. Diethylpropion An appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction. Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Orphenadrine A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. Dexfenfluramine For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet Bromodiphenhydramine For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive. Lisdexamfetamine A central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Mephentermine A sympathomimetic agent used in the treatment of hypotension. MMDA MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present. Midomafetamine Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used... 2,5-Dimethoxyamphetamine Not Available 2,5-Dimethoxy-4-ethylamphetamine Not Available 4-Methoxyamphetamine Not Available Fenethylline Not Available 4-Bromo-2,5-dimethoxyamphetamine Not Available Tenamfetamine An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons... 4-Bromo-2,5-dimethoxyphenethylamine Not Available Fenproporex Fenproporex is used as an appetite suppressant, and anti-obesity agent ; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as... Chlorphentermine Used as an appetite suppressant. Dextroamphetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. Phenethylamine Not Available N-acetylhistamine Not Available Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Histamine An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. Alethine Investigated for use/treatment in blood (blood forming organ disorders, unspecified), lymphoma (unspecified), and multiple myeloma. Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Isoxsuprine A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease. Hexoprenaline Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Benfluorex Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... Hydroxyamphetamine An indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. Iofetamine I-123 Not Annotated Ractopamine Not Annotated Etafedrine A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa. Oxilofrine An amphetamine used to treat a cough associated with inflamed mucosa. Lanicemine Lanicemine has been used in trials studying the treatment and basic science of Depression, Major Depressive Disorder, and Treatment Resistant Major Depressive Disorder. Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... Mebeverine Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms. Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. Tiapride Tiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. Mephedrone Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders. Levosalbutamol A beta-2 adrenergic receptor agonist used to treat COPD and asthma. Bamethan Not Annotated Propanidid An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918) Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Suloctidil Not Annotated Norfenefrine Not Annotated Oxyfedrine Not Annotated Clobenzorex Not Annotated Methoxyphenamine Not Annotated Gepefrine Not Annotated Mefenorex Not Annotated 2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties. Dexverapamil Not Annotated Emopamil Prevents renal injury after warm & cold ischemia. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Methylenedioxyethamphetamine Not Available NAP-226-90 Not Available Hexamethylene diamine Not Available Carmoterol Not Annotated
- Drugs & Drug Targets