Nephrotoxic agents

Name
Nephrotoxic agents
Accession Number
DBCAT003959
Description

This category includes all drugs with the potential to generate kidney damage and to reduce renal function.

Drugs
DrugDrug Description
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
ColistimethateAn antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa.
FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
VancomycinA glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
CefotiamA cephalosporin antibiotic used to treat a variety of bacterial infections.
CefmetazoleA cephalosporin antibiotic used to treat a variety of bacterial infections.
LoracarbefUsed to treat upper respiratory tract bacterial infections, chronic bronchitis, pneumonia, sinusitis, pharyntitis and tonsillitis, skin absceses, urinary tract infections and pyelonephritis caused by E. coli, S. pyogenes, S. aureus,...
CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
CeforanideFor the treatment of infections caused by susceptible organisms.
CefprozilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
CefamandoleA beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections.
CefonicidFor the treatment of bacterial infections caused by susceptible microorganisms.
CefotetanAn antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections.
CefoxitinA semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection.
CefminoxCefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
FlomoxefFlomoxef has been used in trials studying the treatment of Urinary Tract Infection.
CefbuperazoneNot Annotated
CefuroximeA cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.
CefmenoximeUsed to treat female gynecologic and obstetric infections caused by susceptible aerobic (including the gonococcus) and anaerobic bacteria.
CefpiramideFor treatment of severe infections caused by susceptible bacteria such as P. aeruginosa.
CeftazidimeAn injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
CefotaximeA third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.
CefditorenA broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.
CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
CefoperazoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
CeftizoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
LatamoxefLatamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections,...
CefcapeneNot Annotated
CefodizimeA broad-spectrum, third-generation cephalosporin used to treat serious infections caused by susceptible bacteria.
CefsulodinNot Annotated
CefetametNot Annotated
CefepimeA fourth-generation cephalosporin antibiotic used in the treatment of infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.
CefozopranNot Annotated
CefpiromeAn antibiotic indicated in the treatment of a wide variety of infections in the body.
AmikacinAn aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
TobramycinAn aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections.
GentamicinAn aminoglycoside used to treat a wide variety of aerobic infections in the body.
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
StreptomycinAn aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
FramycetinAn aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.
NetilmicinAn aminoglycoside used to treat a wide variety of infections in the body.
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
ParomomycinAn aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
RibostamycinA broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine.
GeneticinGeneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both...
ApramycinAn aminoglycoside antibiotic for veterinary use that is used to treat infections in animals.
Gentamicin C1aNot Available
NeamineNot Available
ArbekacinArbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA).
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
DihydrostreptomycinDihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin...
Hygromycin BHygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.
SisomicinSisomicin has been used in trials studying the treatment of Pyoderma.
PlazomicinAn aminoglycoside antibiotic used to treat complicated urinary tract infections.
DibekacinDibekacin is an aminoglycoside antibiotic marketed in Japan .
MicronomicinMicronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
IsepamicinNot Annotated
BekanamycinAn aminoglycoside antibiotic indicated in the treatment of eye infections.
CapreomycinAn aminoglycoside antibiotic used as an adjunct drug in tuberculosis.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
OlsalazineAn anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis.
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
BenoxaprofenThe use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
MetamizoleAn antipyretic and analgesic drug used to relieve severe and persistent fever and pain.
ZomepiracZomepirac was indicated for the management of mild to severe pain.
ZaltoprofenA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
AzapropazoneNot Available
FelbinacNot Available
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
KebuzoneKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
IsoxicamIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EtofenamateAn NSAID used to treat muscle and joint pain.
EpirizoleEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
LoxoprofenAn NSAID used to treat pain and inflammation in musculoskeletal conditions.
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
ClonixinAn NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders.
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
TepoxalinTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...
FlunixinFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form....
IndobufenA reversible platelet aggregation inhibitor used to prevent coronary and peripheral artery occlusion.
TinoridineTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
FentiazacNot Annotated
SuxibuzoneNot Annotated
BumadizoneBumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
AlminoprofenAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
FlunoxaprofenNot Annotated
FeprazoneNot Annotated
DifenpiramideNot Annotated
NifenazoneNot Annotated
LonazolacNot Annotated
TenidapNot Annotated
BendazacA non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions.
PranoprofenA topical anti-inflammatory agent used for the treatment of non-infectious inflammatory conditions such as blepharitis and conjunctivitis. Pranoprofen ophthalmic solution may also be used post-operatively to manage inflammation.
PropyphenazoneNot Annotated
ProglumetacinA non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis.
GuacetisalNot Annotated
EthenzamideNot Annotated
Carbaspirin calciumAn NSAID indicated in the treatment of short term pain and fever.
MofebutazoneNot Annotated
ProquazoneNot Annotated
BenorilateNot Annotated
PirprofenNot Annotated
AcemetacinA NSAID indicated in the treatment of pain and inflammation.
Imidazole salicylateNot Annotated
BenzydamineA locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy.
AminophenazoneAn analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine.
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
MorniflumateAn NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
EtoricoxibA selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
RobenacoxibRobenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
NimesulideA cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
Niflumic acidA cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
CimicoxibInvestigated for use/treatment in depression.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
FirocoxibUsed for the treatment of pain inflammation and fever in horses and dogs.
TalniflumateTalnifumate is a phthalidyl ester of nifumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis and osteoarthritis ,...
MesalazineAn aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
LornoxicamAn NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
SulfasalazineA salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
AntrafenineAntrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DexibuprofenA pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation.
DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
Trolamine salicylateA medication used to relieve minor aches and pains of the muscles and joints.
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
DexketoprofenAn NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Cephalothin GroupCephalothin group is a solid. This compound belongs to the 1,3-thiazines. These are organic compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atom in ring positions...
Hydrolyzed CephalothinNot Available
CefalotinA broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract.
PentamidineAn antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
CarboplatinA alkylating agent used to treat advanced ovarian cancer.
Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
TenofovirA nucleotide analog indicated in the treatment of HIV infections.
Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
CefapirinA first generation cephalosporin indicated in the treatment of susceptible bacterial infections.
CefadroxilA cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis.
CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
CefradineA first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.
CefacetrileA broad-spectrum first-generation cephalosporin used for the treatment of susceptible bacterial infections.
CefaloridineCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
CefroxadineWas used for the treatment of bacterial infections.
CefatrizineNot Annotated
CefazedoneNot Annotated
CeftezoleNot Annotated
CephaloglycinFor treatment of severe infections caused by susceptible bacteria.
Ceftaroline fosamilAn antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
CeftobiproleA broad spectrum 5th-generation cephalosporin antibacterial indicated for certain kinds of pneumonia, bacteremia, and skin and skin structure infections, including those caused by MRSA.
BacitracinA cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
TacrolimusA calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
AdefovirNot Annotated
Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
Pamidronic acidA bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
InotersenAn antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis.
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
Lithium cationA drug used for the management of bipolar disorder and other psychiatric conditions.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
PhenazopyridineA local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters.
Lithium carbonateA medication used to treat manic episodes of bipolar disorder.
Lithium citrateLithium is used as a mood stabilizer, and is used for treatment of depression and mania. It is often used in bipolar disorder treatment.
GivosiranA 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria.
Drugs & Drug Targets
DrugTargetType
Amphotericin BErgosteroltarget
CisplatinDNAtarget
CisplatinATP-binding cassette sub-family C member 3transporter
CisplatinATP-binding cassette sub-family C member 5transporter
CisplatinATP-binding cassette sub-family C member 2transporter
CisplatinSolute carrier family 22 member 2transporter
CisplatinHigh affinity copper uptake protein 1transporter
CisplatinProtein SLC31A2transporter
CisplatinATP-binding cassette sub-family C member 6transporter
CisplatinCopper-transporting ATPase 2transporter
CisplatinCopper-transporting ATPase 1transporter
CisplatinProstaglandin G/H synthase 2enzyme
CisplatinMyeloperoxidaseenzyme
CisplatinXanthine dehydrogenase/oxidaseenzyme
CisplatinArylamine N-acetyltransferaseenzyme
CisplatinCytochrome P450 2C9enzyme
CisplatinCytochrome P450 2B6enzyme
CisplatinCholinesteraseenzyme
CisplatinCytochrome P450 4A11enzyme
CisplatinBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
CisplatinGlutathione S-transferase theta-1enzyme
CisplatinMetallothionein-1Aenzyme
CisplatinMetallothionein-2enzyme
CisplatinSuperoxide dismutase [Cu-Zn]enzyme
CisplatinGlutathione S-transferase Penzyme
CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CisplatinGlutathione S-transferase Mu 1enzyme
CisplatinDNA-3-methyladenine glycosylasetarget
CisplatinAlpha-2-macroglobulintarget
CisplatinAlbumincarrier
CisplatinSerotransferrintarget
CisplatinCopper transport protein ATOX1target
ColistimethateBacterial outer membranetarget
ColistimethateDihydropteroate synthasetarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetSolute carrier family 22 member 6transporter
FoscarnetMonocarboxylate transporter 1transporter
MannitolMannitol dehydrogenaseenzyme
VancomycinD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
VancomycinAlbumincarrier
Vancomycinalpha1-acid glycoproteincarrier
VancomycinHistamine H1 receptorcarrier
CyclosporineGuided entry of tail-anchored proteins factor CAMLGtarget
CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
CyclosporineCalcineurin subunit B type 2target
CyclosporineCytochrome P450 3A5enzyme
CyclosporineCytochrome P450 3A4enzyme
CyclosporineATP-dependent translocase ABCB1transporter
CyclosporineBile salt export pumptransporter
CyclosporineIleal sodium/bile acid cotransportertransporter
CyclosporineHepatic sodium/bile acid cotransportertransporter
CyclosporineSolute carrier family 22 member 6transporter
CyclosporineATP-binding cassette sub-family C member 10transporter
CyclosporineATP-binding cassette sub-family C member 2transporter
CyclosporineBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
CyclosporineSolute carrier organic anion transporter family member 1B1transporter
CyclosporineCytochrome P450 2C19enzyme
CyclosporineCytochrome P450 2D6enzyme
CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
CyclosporineSolute carrier organic anion transporter family member 1B3transporter
CyclosporineProtein phosphatase 3 catalytic subunit alphatarget
CefotiamPenicillin-binding protein 1Atarget
CefotiamSolute carrier family 22 member 6transporter
CefotiamOrganic anion transporter 3transporter
CefotiamPeptidoglycan synthase FtsItarget
CefmetazolePenicillin binding protein 2atarget
CefmetazoleAlbumincarrier
CefmetazoleSolute carrier family 15 member 1transporter
CefmetazoleSolute carrier family 15 member 2transporter
CefmetazolePenicillin-binding protein 1Atarget
CefmetazolePenicillin-binding protein 1Btarget
CefmetazolePeptidoglycan synthase FtsItarget
CefmetazoleD-alanyl-D-alanine carboxypeptidase DacAtarget
CefmetazoleD-alanyl-D-alanine carboxypeptidase DacCtarget
LoracarbefPenicillin-binding protein 1Atarget
LoracarbefSolute carrier family 15 member 1transporter
LoracarbefSolute carrier family 15 member 2transporter
LoracarbefPenicillin-binding protein 3target
CefaclorPenicillin-binding protein 1Atarget
CefaclorSolute carrier family 15 member 1transporter
CefaclorSolute carrier family 15 member 2transporter
CefaclorPenicillin-binding protein 3target
CefaclorMyeloperoxidaseenzyme
CefaclorOrganic anion transporter 3transporter
CefaclorBile salt export pumptransporter
CeforanidePenicillin-binding protein 2target
CefprozilPenicillin-binding protein 1Atarget
CefprozilPenicillin-binding protein 2xtarget
CefprozilPenicillin-binding protein 2Btarget
CefamandoleSolute carrier family 22 member 6transporter
CefamandoleOrganic anion transporter 3transporter
CefamandoleSolute carrier family 22 member 11transporter
CefamandoleSolute carrier family 22 member 7transporter
CefamandolePenicillin-binding protein 2target
CefonicidAlbumincarrier
CefonicidPenicillin-binding protein 1Atarget
CefonicidPeptidoglycan synthase FtsItarget
CefonicidPenicillin-binding protein 1Btarget
CefonicidD-alanyl-D-alanine carboxypeptidase DacBtarget
CefonicidPenicillin-binding protein 2target
CefotetanAlbumincarrier
CefotetanPenicillin-binding protein 3target
CefoxitinPenicillin-binding protein 1Atarget
CefoxitinPenicillin-binding protein 1Btarget
CefoxitinPeptidoglycan synthase FtsItarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacAtarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacBtarget
CefoxitinD-alanyl-D-alanine carboxypeptidase DacCtarget
CefoxitinD-alanyl-D-alanine endopeptidasetarget
CefoxitinBeta-lactamaseenzyme
CefoxitinPenicillin-binding protein 3target
CefoxitinPenicillin-binding protein 1btarget
CefoxitinPenicillin-binding protein 2atarget
CefoxitinPenicillin-binding protein 1Atarget
CefoxitinPenicillin-binding protein 2Btarget
CefuroximePenicillin-binding protein 1Atarget
CefuroximeSolute carrier family 15 member 1transporter
CefuroximeSolute carrier family 15 member 2transporter
CefmenoximePenicillin-binding protein 1Atarget
CefmenoximePeptidoglycan synthase FtsItarget
CefpiramidePenicillin binding protein 2atarget
CefpiramideAlbumincarrier
CefpiramidePeptidoglycan synthase FtsItarget
CefpiramidePenicillin-binding protein 1Btarget
CefpiramidePenicillin-binding protein 1Atarget
CefpiramidePenicillin-binding protein 1Btarget
CefpiramideD-alanyl-D-alanine carboxypeptidase DacCtarget
CefpiramidePenicillin-binding protein 1Atarget
CeftazidimeSolute carrier family 22 member 6transporter
CeftazidimePeptidoglycan synthase FtsItarget
CeftazidimePenicillin-binding protein 1Atarget
CeftazidimePenicillin-binding protein 1Btarget
CeftazidimePenicillin-binding protein 2target
CeftazidimeAlbumincarrier
CeftazidimeBeta-lactamase Toho-1target
CefotaximePenicillin-binding protein 3target
CefotaximeSolute carrier family 15 member 1transporter
CefotaximeSolute carrier family 15 member 2transporter
CefotaximeSolute carrier family 22 member 6transporter
CefotaximeOrganic anion transporter 3transporter
CefotaximeSolute carrier family 22 member 11transporter
CefotaximeSolute carrier family 22 member 7transporter
CefotaximePenicillin-binding protein 1btarget
CefotaximePenicillin-binding protein 2atarget
CefotaximePenicillin-binding protein 1Atarget
CefotaximePenicillin-binding protein 2Btarget
CefotaximeSolute carrier family 22 member 6target
CefotaximeOrganic anion transporter 3target
CefotaximeSolute carrier family 22 member 11target
CefotaximeSolute carrier family 22 member 7target
CefotaximeSolute carrier family 15 member 1target
CefotaximeAlbumintarget
CefotaximeBeta-lactamasetarget
CefotaximeSolute carrier family 15 member 2target
CefditorenPenicillin-binding protein 1Atarget
CefditorenPenicillin-binding protein 2Btarget
CeftriaxoneAlbumincarrier
CeftriaxoneSolute carrier family 15 member 1transporter
CeftriaxoneSolute carrier family 15 member 2transporter
CeftriaxoneSolute carrier family 22 member 6transporter
CeftriaxoneOrganic anion transporter 3transporter
CeftriaxoneSolute carrier family 22 member 11transporter
CeftriaxonePenicillin-binding protein 2Btarget
CeftriaxoneGlutamine synthetaseenzyme
CeftriaxoneSolute carrier family 22 member 11target
CeftriaxoneSolute carrier family 22 member 6target
CeftriaxoneOrganic anion transporter 3target
CeftriaxoneSolute carrier family 15 member 1target
CeftriaxoneATP-dependent translocase ABCB1transporter
CefoperazoneAlbumincarrier
CefoperazoneSolute carrier family 22 member 6transporter
CefoperazoneOrganic anion transporter 3transporter
CefoperazoneSolute carrier family 22 member 11transporter
CefoperazoneSolute carrier family 22 member 7transporter
CefoperazonePeptidoglycan synthase FtsItarget
CefoperazonePenicillin-binding protein 1Btarget
CefoperazonePenicillin-binding protein 2target
CefoperazonePenicillin-binding protein 1Atarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacCtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacAtarget
CefoperazoneD-alanyl-D-alanine carboxypeptidase DacBtarget
CefoperazonePenicillin-binding protein 1Atarget
CefoperazonePenicillin-binding protein 1Btarget
CeftizoximeSolute carrier family 15 member 1transporter
CeftizoximePenicillin-binding protein 1Atarget
CeftizoximePenicillin-binding protein 1Btarget
CeftizoximeSolute carrier family 22 member 6transporter
CeftizoximeOrganic anion transporter 3transporter
CeftizoximePeptidoglycan transpeptidasetarget
CeftizoximeD-alanyl-D-alanine carboxypeptidase DacCtarget
CeftibutenSolute carrier family 15 member 1transporter
CeftibutenSolute carrier family 15 member 2transporter
CeftibutenPeptidoglycan synthase FtsItarget
CeftibutenPenicillin-binding protein 1Atarget
CeftibutenPenicillin-binding protein 1Btarget
CeftibutenPenicillin-binding protein 2target
CeftibutenSolute carrier family 22 member 6transporter
CeftibutenOrganic anion transporter 3transporter
CefpodoximePeptidoglycan synthase FtsItarget
LatamoxefPenicillin-binding protein 3target
LatamoxefPenicillin-binding protein 1Atarget
LatamoxefPenicillin-binding protein 1Btarget
LatamoxefD-alanyl-D-alanine carboxypeptidase DacBtarget
LatamoxefPeptidoglycan synthase FtsItarget
CefepimeOrganic cation/carnitine transporter 2transporter
CefepimeSolute carrier family 15 member 1transporter
CefepimeSolute carrier family 15 member 2transporter
CefepimePenicillin-binding protein 2target
CefepimePeptidoglycan synthase FtsItarget
CefepimeCell division proteintarget
CefepimePenicillin-binding protein 2target
CefepimePenicillin-binding protein 1Atarget
CefepimePenicillin-binding protein 1Btarget
CefepimePenicillin-binding protein 1Btarget
CefozopranDihydropteroate synthasetarget
Amikacin30S ribosomal protein S12target
Tobramycin16S ribosomal RNAtarget
TobramycinBacterial outer membranetarget
TobramycinCytoplasmic membranetarget
Tobramycin23S ribosomal RNAtarget
Gentamicin30S ribosomal protein S12target
Gentamicin16S ribosomal RNAtarget
GentamicinNH(3)-dependent NAD(+) synthetasetarget
GentamicinDihydrofolate reductasetarget
Gentamicin23S ribosomal RNAtarget
GentamicinBacterial outer membranetarget
GentamicinCytoplasmic membranetarget
GentamicinLow-density lipoprotein receptor-related protein 2transporter
GentamicinSolute carrier family 22 member 2transporter
GentamicinATP-binding cassette sub-family C member 2transporter
Neomycin30S ribosomal protein S12target
Neomycin16S ribosomal RNAtarget
NeomycinExtracellular calcium-sensing receptortarget
Streptomycin30S ribosomal protein S12target
Streptomycin16S ribosomal RNAtarget
StreptomycinProtein-arginine deiminase type-4target
Streptomycin23S ribosomal RNAtarget
StreptomycinBacterial outer membranetarget
StreptomycinCytoplasmic membranetarget
Framycetin30S ribosomal protein S12target
Framycetin16S ribosomal RNAtarget
FramycetinC-X-C chemokine receptor type 4target
Netilmicin30S ribosomal protein S12target
Netilmicin16S ribosomal RNAtarget
Kanamycin30S ribosomal protein S12target
Kanamycin16S ribosomal RNAtarget
KanamycinAminoglycoside 2'-N-acetyltransferaseenzyme
KanamycinKanamycin nucleotidyltransferaseenzyme
KanamycinAminoglycoside 3'-phosphotransferaseenzyme
Paromomycin16S ribosomal RNAtarget
Paromomycin30S ribosomal protein S10target
ParomomycinSmall ribosomal subunit protein uS2target
ParomomycinRibosomal protein uL16-liketarget
RibostamycinProtein disulfide-isomerasetarget
Ribostamycin30S ribosomal protein S12target
RibostamycinAminoglycoside N(6')-acetyltransferase type 1target
RibostamycinAminoglycoside 2'-N-acetyltransferasetarget
RibostamycinAminoglycoside 2'-N-acetyltransferaseenzyme
GeneticinOrnithine decarboxylasetarget
Apramycin16S ribosomal RNAtarget
Gentamicin C1a30S ribosomal protein S12target
Gentamicin C1a16S ribosomal RNAtarget
Arbekacin30S ribosomal protein S12target
PuromycinRibosomal protein uL16-liketarget
PuromycinLarge ribosomal subunit protein uL13target
PuromycinLarge ribosomal subunit protein uL14target
PuromycinLarge ribosomal subunit protein eL15target
PuromycinLarge ribosomal subunit protein eL19target
PuromycinLarge ribosomal subunit protein uL23target
PuromycinProbable ribosome biogenesis protein RLP24target
PuromycinRibosomal protein uL24-liketarget
PuromycinLarge ribosomal subunit protein uL2target
PuromycinLarge ribosomal subunit protein eL37target
PuromycinLarge ribosomal subunit protein uL3target
PuromycinLarge ribosomal subunit protein uL5target
PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
PlazomicinMultidrug and toxin extrusion protein 1transporter
PlazomicinMultidrug and toxin extrusion protein 2transporter
Plazomicin30S ribosomal protein S14target
Plazomicin30S ribosomal protein S11target
PlazomicinrRNA methyltransferase 2, mitochondrialtarget
Capreomycin16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyAtarget
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenAlbumincarrier
IbuprofenATP-binding cassette sub-family C member 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenOrganic anion transporter 3transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenATP-dependent translocase ABCB1transporter
IbuprofenUDP-glucuronosyltransferase 1A3enzyme
IbuprofenUDP-glucuronosyltransferase 1A9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
IbuprofenC-X-C chemokine receptor type 1target
IbuprofenC-X-C chemokine receptor type 2target
IbuprofenInterleukin-8target
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
OlsalazineSolute carrier family 2, facilitated glucose transporter member 9transporter
OlsalazineSolute carrier family 22 member 6transporter
OlsalazineOrganic anion transporter 3transporter
OlsalazineSodium-dependent phosphate transporter 1transporter
OlsalazineSodium/Potassium Transporting ATPasetransporter
OlsalazineHuman Cyclooxygenasestarget
OlsalazineXanthine dehydrogenase/oxidasetarget
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneAlbumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
OxyphenbutazoneAlbumintarget
BenoxaprofenAcetyl-CoA acetyltransferase, mitochondrialtarget
MetamizoleProstaglandin G/H synthase 1target
MetamizoleCytochrome P450 2B6enzyme
MetamizoleCytochrome P450 3A4enzyme
ZomepiracProstaglandin D2 receptor 2target
ZomepiracCytochrome P450 3A4enzyme
ZomepiracAlbumincarrier
ZomepiracProstaglandin G/H synthase 1target
ZomepiracProstaglandin G/H synthase 2target
ZaltoprofenUDP-glucuronosyltransferase 2B7enzyme
ZaltoprofenCytochrome P450 2C9enzyme
ZaltoprofenProstaglandin G/H synthase 1enzyme
AzapropazoneAlbumincarrier
FelbinacProcathepsin Ltarget
FelbinacProstaglandin G/H synthase 1target
FelbinacProstaglandin G/H synthase 2target
IndoprofenPyruvate kinase PKMtarget
IndoprofenFatty acid-binding protein, livertarget
IndoprofenC-X-C chemokine receptor type 2target
IndoprofenC-X-C chemokine receptor type 1target
IndoprofenProstaglandin G/H synthase 2target
IndoprofenProstaglandin G/H synthase 1target
IbuproxamPolyunsaturated fatty acid 5-lipoxygenasetarget
FenbufenProstaglandin G/H synthase 2target
FenbufenProstaglandin G/H synthase 1target
EtofenamateThyroxine-binding globulincarrier
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1A1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1A9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1A10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3enzyme
PropacetamolSulfotransferase 1E1enzyme
PropacetamolSulfotransferase 2A1enzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
TepoxalinInterleukin-4target
TepoxalinPolyunsaturated fatty acid 5-lipoxygenasetarget
AlclofenacProstaglandin G/H synthase 2target
TenidapPolyunsaturated fatty acid 5-lipoxygenasetarget
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
PranoprofenHuman Cyclooxygenasesenzyme
PranoprofenAlbumincarrier
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
BenzydamineProstaglandin G/H synthase 1target
BenzydamineProstaglandin G/H synthase 2target
AminophenazoneCytochrome P450 2C19enzyme
AminophenazoneCytochrome P450 1A2enzyme
AminophenazoneCytochrome P450 2C8enzyme
AminophenazoneSolute carrier family 22 member 6transporter
AminophenazoneCytochrome P450 2C9enzyme
AminophenazoneCytochrome P450 2D6enzyme
AminophenazoneCytochrome P450 3A4enzyme
AminophenazoneCytochrome P450 2C18enzyme
AminophenazoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
SC-236Prostaglandin G/H synthase 2target
NS-398Cyclooxygenase 2target
NS-398Prostaglandin G/H synthase 2enzyme
NS-398Prostaglandin G/H synthase 2target
NitroaspirinProstaglandin G/H synthase 1target
NitroaspirinProstaglandin G/H synthase 2target
MorniflumatePolyunsaturated fatty acid 5-lipoxygenasetarget
MorniflumateProstaglandin G/H synthase 2target
MorniflumatePolyunsaturated fatty acid 5-lipoxygenaseenzyme
MorniflumateProstaglandin G/H synthase 2enzyme
MorniflumateLeukotriene B4 receptor 1target
MorniflumateThromboxane A2 receptortarget
MorniflumateUDP-glucuronosyltransferase 1A9enzyme
MorniflumateProstaglandin G/H synthase 1target
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibATP-binding cassette sub-family C member 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1A9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1A9enzyme
LumiracoxibCytochrome P450 1A2enzyme
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
ParecoxibLactotransferrintarget
ParecoxibProstaglandin G/H synthase 2target
ParecoxibCytochrome P450 3A4enzyme
ParecoxibCytochrome P450 2C9enzyme
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
Nabumetone11-beta-hydroxysteroid dehydrogenase 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneAlbumincarrier
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibATP-binding cassette sub-family C member 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibATP-dependent translocase ABCB1transporter
CelecoxibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
CelecoxibProstaglandin G/H synthase 2enzyme
CelecoxibSialidase-1target
CelecoxibSignal transducer and activator of transcription 3target
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1A9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacAlbumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1A3enzyme
EtodolacUDP-glucuronosyltransferase 1A10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
RobenacoxibCyclooxygenase 2target
CarprofenProstaglandin G/H synthase 2target
CarprofenProstaglandin G/H synthase 1target
CarprofenSolute carrier family 22 member 6transporter
MeloxicamProstaglandin G/H synthase 2target
MeloxicamCytochrome P450 2C9enzyme
MeloxicamProstaglandin G/H synthase 1target
MeloxicamCytochrome P450 3A4enzyme
MeloxicamATP-binding cassette sub-family C member 4transporter
Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MeloxicamCytochrome P450 2C8enzyme
MeloxicamAlbumincarrier
MeloxicamHuman vesicular glutamate transporterstransporter
BromfenacProstaglandin G/H synthase 1target
BromfenacProstaglandin G/H synthase 2target
BromfenacProstaglandin G/H synthase 2enzyme
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
NimesulideTumor necrosis factor ligand superfamily member 10target
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1A9target
Niflumic acidUDP-glucuronosyltransferase 1A9enzyme
CimicoxibProstaglandin G/H synthase 2target
CimicoxibProstaglandin G/H synthase 2enzyme
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
FirocoxibProstaglandin G/H synthase 2target
TalniflumateProstaglandin G/H synthase 1target
TalniflumateProstaglandin G/H synthase 2target
TalniflumateChloride channel protein ClC-Katarget
TalniflumateProstaglandin G/H synthase 1enzyme
TalniflumateProstaglandin G/H synthase 2enzyme
MesalazineProstaglandin G/H synthase 1target
MesalazineProstaglandin G/H synthase 2target
MesalazinePeroxisome proliferator-activated receptor gammatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
MesalazinePolyunsaturated fatty acid 5-lipoxygenasetarget
MesalazineArylamine N-acetyltransferase 1enzyme
MesalazineSolute carrier organic anion transporter family member 1B1transporter
MesalazineSolute carrier organic anion transporter family member 1B3transporter
MesalazineSolute carrier organic anion transporter family member 2B1transporter
MesalazineNitric oxide synthase, inducibletarget
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1A9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinAlbumincarrier
IndomethacinATP-binding cassette sub-family C member 3transporter
IndomethacinATP-binding cassette sub-family C member 4transporter
IndomethacinATP-binding cassette sub-family C member 6transporter
IndomethacinATP-dependent translocase ABCB1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinOrganic anion transporter 3transporter
IndomethacinATP-binding cassette sub-family C member 2transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinHepatic sodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1A1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
IndomethacinInterferon-induced, double-stranded RNA-activated protein kinasetarget
IndomethacinHuman Cyclooxygenasestarget
KetorolacProstaglandin G/H synthase 1target
KetorolacProstaglandin G/H synthase 2target
KetorolacUDP-glucuronosyltransferase 2B7enzyme
KetorolacCytochrome P450 2C8enzyme
KetorolacCytochrome P450 2C9enzyme
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamOrganic anion transporter 3transporter
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinAlbumincarrier
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamAlbumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamOrganic anion transporter 3transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenAlbumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenAlbumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenATP-dependent translocase ABCB1transporter
NaproxenUDP-glucuronosyltransferase 1A3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1A7enzyme
NaproxenUDP-glucuronosyltransferase 1A8enzyme
NaproxenUDP-glucuronosyltransferase 1A9enzyme
NaproxenUDP-glucuronosyltransferase 1A10enzyme
NaproxenOrganic anion transporter 3transporter
NaproxenPancreatic triacylglycerol lipasetarget
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalAlbumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1A8enzyme
DiflunisalUDP-glucuronosyltransferase 1A9enzyme
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1A1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenAlbumincarrier
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidPolyunsaturated fatty acid 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidATP-dependent translocase ABCB1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acidEndoplasmic reticulum chaperone BiPtarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidOrganic anion transporter 3transporter
Acetylsalicylic acidSialidase-1target
Acetylsalicylic acid3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenAlbumincarrier
KetoprofenATP-binding cassette sub-family C member 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenOrganic anion transporter 3transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1A1enzyme
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazidePolyunsaturated fatty acid 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentAcyl-CoA (8-3)-desaturasetarget
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentAlbumincarrier
IcosapentFatty acid-binding protein, braintarget
IcosapentPolyunsaturated fatty acid 5-lipoxygenasetarget
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenAlbumincarrier
FlurbiprofenATP-binding cassette sub-family C member 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1A9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidAlbumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1A9enzyme
Mefenamic acidCytochrome P450 1A2enzyme
Mefenamic acidUDP-glucuronosyltransferase 2B7enzyme
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
SulindacProstaglandin G/H synthase 2target
SulindacAldo-keto reductase family 1 member B1target
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacAlbumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
Salicylic acidAlbumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidOrganic anion transporter 3transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Salicylic acidCarbonic anhydrase 6target
Salicylic acidCarbonic anhydrase 12target
Salicylic acidCarbonic anhydrase 2target
Salicylic acidCarbonic anhydrase 4target
Salicylic acidCarbonic anhydrase 1target
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
Magnesium salicylateAlbumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
LornoxicamCytochrome P450 2C9enzyme
LornoxicamProstaglandin G/H synthase 1target
LornoxicamProstaglandin G/H synthase 2target
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneOrganic anion transporter 3transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
SulfasalazineATP-binding cassette sub-family C member 2transporter
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazinePolyunsaturated fatty acid 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
SulfasalazineAlbumincarrier
SulfasalazineCystine/glutamate transportertarget
SulfasalazineNuclear factor NF-kappa-B p105 subunittarget
SulfasalazineNuclear factor NF-kappa-B p100 subunittarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineHepatic sodium/bile acid cotransportertransporter
SulfasalazineBroad substrate specificity ATP-binding cassette transporter ABCG2target
SulfasalazineTranscription factor p65target
SulfasalazineProto-oncogene c-Reltarget
SulfasalazineTranscription factor RelBtarget
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
AntrafenineProstaglandin G/H synthase 1target
AntrafenineProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DexibuprofenProstaglandin G/H synthase 1target
DexibuprofenProstaglandin G/H synthase 2target
DexibuprofenApoptosis regulator Bcl-2target
DexibuprofenThrombomodulintarget
DexibuprofenTissue-type plasminogen activatortarget
DexibuprofenFatty acid-binding protein, intestinaltarget
DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DexibuprofenCytochrome P450 2C9enzyme
DexibuprofenAlbumincarrier
DexibuprofenATP-binding cassette sub-family C member 4transporter
DexibuprofenMultidrug resistance-associated protein 1transporter
DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DexibuprofenSolute carrier family 22 member 6transporter
DexibuprofenOrganic anion transporter 3transporter
DexibuprofenSolute carrier family 22 member 11transporter
DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DexibuprofenATP-dependent translocase ABCB1transporter
DexibuprofenUDP-glucuronosyltransferase 1A1enzyme
DexibuprofenUDP-glucuronosyltransferase 1A3enzyme
DexibuprofenUDP-glucuronosyltransferase 1A9enzyme
DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenCytochrome P450 2C8enzyme
DexibuprofenCytochrome P450 2C19enzyme
DexibuprofenSolute carrier family 15 member 1target
DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DexibuprofenProtein S100-A7target
DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DroxicamProstaglandin G/H synthase 1target
DroxicamProstaglandin G/H synthase 2target
Trolamine salicylateProstaglandin G/H synthase 1target
Trolamine salicylateProstaglandin G/H synthase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacPolyamine deacetylase HDAC10target
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacAlbumincarrier
DiclofenacATP-binding cassette sub-family C member 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacOrganic anion transporter 3transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1A3enzyme
DiclofenacUDP-glucuronosyltransferase 1A9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacPolyunsaturated fatty acid 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacATP-dependent translocase ABCB1transporter
Cephalothin GroupBeta-lactamase Toho-1target
Cephalothin GroupD-alanyl-D-alanine carboxypeptidasetarget
Hydrolyzed CephalothinBeta-lactamasetarget
Hydrolyzed CephalothinBeta-lactamasetarget
CefalotinPenicillin-binding protein 1Atarget
CefalotinD-alanyl-D-alanine carboxypeptidasetarget
CefalotinBeta-lactamasetarget
CefalotinOrganic cation/carnitine transporter 2transporter
CefalotinSolute carrier family 15 member 1transporter
CefalotinSolute carrier family 15 member 2transporter
CefalotinSolute carrier family 22 member 6transporter
CefalotinOrganic anion transporter 3transporter
CefalotinSolute carrier family 22 member 11transporter
CefalotinSolute carrier family 22 member 7transporter
CefalotinPenicillin-binding protein 1Atarget
CefalotinPenicillin-binding protein 1btarget
CefalotinPenicillin-binding protein 3target
CefalotinPenicillin-binding protein 2atarget
CefalotinPenicillin-binding protein 2Btarget
CefalotinAlbumincarrier
PentamidineDNAtarget
PentamidineCytochrome P450 2C19enzyme
PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
PentamidineCytochrome P450 2D6enzyme
PentamidineCytochrome P450 1A1enzyme
PentamidineCytochrome P450 3A5enzyme
PentamidineCytochrome P450 4A11enzyme
PentamidineTryptase alpha/beta-1target
CarboplatinDNAtarget
CarboplatinHigh affinity copper uptake protein 1transporter
CarboplatinProtein SLC31A2transporter
CarboplatinXanthine dehydrogenase/oxidaseenzyme
CarboplatinMyeloperoxidaseenzyme
CarboplatinGlutathione S-transferase theta-1enzyme
CarboplatinMetallothionein-1Aenzyme
CarboplatinMetallothionein-2enzyme
CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
CarboplatinGlutathione S-transferase Penzyme
CarboplatinGlutathione S-transferase Mu 1enzyme
CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CarboplatinCopper-transporting ATPase 1transporter
CarboplatinCopper-transporting ATPase 2transporter
CarboplatinBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
CarboplatinATP-binding cassette sub-family C member 2transporter
Tenofovir alafenamideReverse transcriptase/RNaseHtarget
Tenofovir alafenamideATP-dependent translocase ABCB1transporter
Tenofovir alafenamideATP-binding cassette sub-family C member 4transporter
Tenofovir alafenamideSolute carrier family 22 member 6transporter
Tenofovir alafenamideOrganic anion transporter 3transporter
Tenofovir alafenamideLysosomal protective proteinenzyme
Tenofovir alafenamideLiver carboxylesterase 1enzyme
Tenofovir alafenamideBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
Tenofovir alafenamideReverse transcriptasetarget
Tenofovir alafenamideDNA polymerasetarget
Tenofovir alafenamideAlbumincarrier
Tenofovir alafenamideCytochrome P450 3A4enzyme
Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
Tenofovir alafenamideGag-Pol polyproteintarget
TenofovirATP-dependent translocase ABCB1transporter
TenofovirSolute carrier family 22 member 6transporter
TenofovirOrganic anion transporter 3transporter
TenofovirATP-binding cassette sub-family C member 4transporter
TenofovirNucleoside diphosphate kinase Aenzyme
TenofovirNucleoside diphosphate kinase Benzyme
TenofovirAdenylate kinase isoenzyme 1enzyme
TenofovirAdenylate kinase 2, mitochondrialenzyme
TenofovirReverse transcriptase/RNaseHtarget
TenofovirReverse transcriptasetarget
TenofovirDNA polymerasetarget
TenofovirAlbumincarrier
TenofovirGag-Pol polyproteintarget
Tenofovir disoproxilReverse transcriptase/RNaseHtarget
Tenofovir disoproxilSolute carrier family 22 member 6transporter
Tenofovir disoproxilOrganic anion transporter 3transporter
Tenofovir disoproxilATP-binding cassette sub-family C member 10transporter
Tenofovir disoproxilATP-binding cassette sub-family C member 4transporter
Tenofovir disoproxilATP-binding cassette sub-family C member 2transporter
Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
Tenofovir disoproxilATP-dependent translocase ABCB1transporter
Tenofovir disoproxilNucleoside diphosphokinaseenzyme
Tenofovir disoproxilCreatine Kinasesenzyme
Tenofovir disoproxilProtein Ptarget
Tenofovir disoproxilGag-Pol polyproteintarget
CephalexinAlbumincarrier
CephalexinOrganic cation/carnitine transporter 2transporter
CephalexinSolute carrier family 15 member 1transporter
CephalexinSolute carrier family 15 member 2transporter
CephalexinSolute carrier family 22 member 6transporter
CephalexinOrganic anion transporter 3transporter
CephalexinMultidrug and toxin extrusion protein 1transporter
CephalexinPenicillin-binding protein 3target
CephalexinPenicillin-binding protein 2atarget
CephalexinPenicillin-binding protein 1btarget
CephalexinPenicillin-binding protein 1Atarget
CephalexinPenicillin-binding protein 2Btarget
CefapirinPenicillin-binding protein 1Atarget
CefadroxilOrganic cation/carnitine transporter 2transporter
CefadroxilSolute carrier family 15 member 1transporter
CefadroxilSolute carrier family 15 member 2transporter
CefadroxilSolute carrier family 22 member 6transporter
CefadroxilOrganic anion transporter 3transporter
CefadroxilPenicillin-binding protein 3target
CefadroxilPenicillin-binding protein 1Atarget
CefadroxilPenicillin-binding protein 1btarget
CefadroxilPenicillin-binding protein 2Btarget
CefazolinSerum paraoxonase/arylesterase 1target
CefazolinAlbumincarrier
CefazolinSolute carrier family 22 member 6transporter
CefazolinOrganic anion transporter 3transporter
CefazolinSolute carrier family 22 member 11transporter
CefazolinPenicillin-binding protein 1Atarget
CefazolinPenicillin-binding protein 1Btarget
CefazolinPenicillin-binding protein 2target
CefazolinPenicillin-binding protein 1Ctarget
CefazolinPeptidoglycan synthase FtsItarget
CefazolinATP-binding cassette sub-family C member 4transporter
CefazolinThiopurine S-methyltransferaseenzyme
CefazolinInterleukin-15target
CefazolinInterleukin-2target
CefradineOrganic cation/carnitine transporter 2transporter
CefradineSolute carrier family 15 member 1transporter
CefradineSolute carrier family 15 member 2transporter
CefradineSolute carrier family 22 member 6transporter
CefradinePenicillin-binding protein 1Atarget
CefradineCytochrome P450 3A4enzyme
CefradineMultidrug and toxin extrusion protein 1transporter
CefacetrilePenicillin-binding protein 1Atarget
CefacetrilePenicillin-binding protein 1Btarget
CefacetrileSolute carrier family 22 member 6transporter
CefacetrileOrganic anion transporter 3transporter
CefaloridineSolute carrier family 22 member 6transporter
CefaloridineOrganic anion transporter 3transporter
CefroxadineBeta-lactamaseenzyme
CefroxadinePenicillin-binding protein 1Btarget
CephaloglycinOrganic cation/carnitine transporter 2transporter
CephaloglycinPenicillin-binding protein 1Btarget
CeftobiproleMecAtarget
CeftobiprolePenicillin-binding protein 2xtarget
CeftobiprolePeptidoglycan synthase FtsItarget
CeftobiprolePenicillin-binding protein 2Btarget
CeftobiprolePenicillin-binding protein 2Xtarget
CeftobiproleSolute carrier organic anion transporter family member 1B1transporter
CeftobiproleSolute carrier organic anion transporter family member 1B3transporter
CeftobiproleATP-binding cassette sub-family C member 2transporter
CeftobiproleBile salt export pumptransporter
BacitracinAlpha-2-macroglobulintarget
BacitracinInsulin-degrading enzymetarget
BacitracinC55-isoprenyl pyrophosphatetarget
BacitracinBacitracin transport ATP-binding protein BcrAtransporter
BacitracinBacitracin transport permease protein BCRBtransporter
BacitracinBacitracin transport permease protein BcrCtransporter
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirOrganic anion transporter 3transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirAlbumincarrier
ValaciclovirThymidine kinasetarget
ValaciclovirDNA polymerase catalytic subunittarget
ValaciclovirSolute carrier family 15 member 1transporter
ValaciclovirSolute carrier family 15 member 2transporter
ValaciclovirOrganic anion transporter 3transporter
ValaciclovirSolute carrier family 22 member 6transporter
ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
ValaciclovirIleal sodium/bile acid cotransportertransporter
ValaciclovirGuanylate kinaseenzyme
ValaciclovirThymidine kinaseenzyme
MethotrexateDihydrofolate reductasetarget
MethotrexateAldehyde oxidaseenzyme
MethotrexateMethylenetetrahydrofolate reductase (NADPH)enzyme
MethotrexateAlbumincarrier
MethotrexateATP-binding cassette sub-family C member 3transporter
MethotrexateATP-binding cassette sub-family C member 4transporter
MethotrexateMultidrug resistance-associated protein 1transporter
MethotrexateSolute carrier family 22 member 6transporter
MethotrexateATP-binding cassette sub-family C member 10transporter
MethotrexateOrganic anion transporter 3transporter
MethotrexateATP-binding cassette sub-family C member 2transporter
MethotrexateATP-dependent translocase ABCB1transporter
MethotrexateSolute carrier organic anion transporter family member 1A2transporter
MethotrexateMonocarboxylate transporter 1transporter
MethotrexateATP-binding cassette sub-family C member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1B3transporter
MethotrexateSolute carrier family 22 member 11transporter
MethotrexateSolute carrier organic anion transporter family member 1C1transporter
MethotrexateSolute carrier organic anion transporter family member 3A1transporter
MethotrexateBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
MethotrexateSolute carrier family 22 member 7transporter
MethotrexateSolute carrier organic anion transporter family member 1B1transporter
Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MethotrexateProton-coupled folate transportertransporter
MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
MethotrexateGamma-glutamyl hydrolaseenzyme
MethotrexateDihydrofolate reductaseenzyme
MethotrexateThymidylate synthaseenzyme
MethotrexateBifunctional purine biosynthesis protein ATICenzyme
MethotrexateSolute carrier organic anion transporter family member 4C1transporter
MethotrexateReduced folate transportertransporter
MethotrexateFolate receptor alphatransporter
MethotrexateCytochrome P450 3A4enzyme
MethotrexateThymidylate synthasetarget
MethotrexateBifunctional purine biosynthesis protein ATICtarget
MethotrexateFolate receptor betatransporter
MethotrexateSolute carrier family 15 member 1transporter
MethotrexateProton-coupled amino acid transporter 1transporter
MethotrexateCarboxypeptidase G2enzyme
MethotrexateProton-coupled folate transportertarget
MethotrexateReduced folate transportertarget
TacrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
TacrolimusCytochrome P450 3A4enzyme
TacrolimusCytochrome P450 3A5enzyme
TacrolimusATP-dependent translocase ABCB1transporter
TacrolimusCholesterol transporter ABCA5transporter
TacrolimusAlbumincarrier
TacrolimusAlpha-1-acid glycoprotein 1carrier
TacrolimusSolute carrier organic anion transporter family member 1B1transporter
TacrolimusProtein phosphatase 3 catalytic subunit alphatarget
AdefovirProtein Ptarget
AdefovirDNA polymerase catalytic subunittarget
Adefovir dipivoxilProtein Ptarget
Adefovir dipivoxilSolute carrier family 22 member 6transporter
Adefovir dipivoxilATP-binding cassette sub-family C member 4transporter
Adefovir dipivoxilATP-binding cassette sub-family C member 5transporter
Adefovir dipivoxilSolute carrier family 22 member 3transporter
Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
CidofovirDNA polymerase catalytic subunittarget
CidofovirSolute carrier family 22 member 6transporter
CidofovirThymidine phosphorylaseenzyme
CidofovirDNA polymerase catalytic subunittarget
Pamidronic acidFarnesyl pyrophosphate synthasetarget
Pamidronic acidHydroxylapatitetarget
Pamidronic acidGeranylgeranyl pyrophosphate synthasetarget
Pamidronic acidCaspase-3target
Pamidronic acidCaspase-9target
LopinavirPol polyproteintarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirATP-dependent translocase ABCB1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirAlbumincarrier
InotersenTransthyretin mRNAtarget
InotersenTransthyretintarget
ColistinBacterial outer membranetarget
ColistinDihydropteroate synthasetarget
Lithium cationInositol monophosphatase 2target
Lithium cationInositol monophosphatase 1target
Lithium cationGlycogen synthase kinase-3 betatarget
Lithium cationGlutamate receptor 3target
AtazanavirPol polyproteintarget
AtazanavirCytochrome P450 3A4enzyme
AtazanavirCytochrome P450 2C9enzyme
AtazanavirATP-dependent translocase ABCB1transporter
AtazanavirMultidrug resistance-associated protein 1transporter
AtazanavirAlbumincarrier
AtazanavirUDP-glucuronosyltransferase 1A1enzyme
AtazanavirSolute carrier organic anion transporter family member 1B1transporter
AtazanavirSolute carrier organic anion transporter family member 1B3transporter
AtazanavirCytochrome P450 2C8enzyme
AtazanavirBile salt export pumptransporter
Atazanaviralpha1-acid glycoproteincarrier
AtazanavirCytochrome P450 1A2enzyme
AtazanavirSolute carrier organic anion transporter family member 2B1transporter
AtazanavirCytochrome P450 3A5enzyme
AtazanavirCytochrome P450 3A7enzyme
AtazanavirGag-Pol polyproteintarget
FurosemideSolute carrier family 12 member 1target
FurosemideAlbumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideOrganic cation/carnitine transporter 2transporter
FurosemideOrganic anion transporter 3transporter
FurosemideATP-binding cassette sub-family C member 2transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1A1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
Etacrynic acidSolute carrier family 12 member 1target
Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
Etacrynic acidGlutathione S-transferase A2enzyme
Etacrynic acidAlbumincarrier
Etacrynic acidSolute carrier family 22 member 6transporter
Etacrynic acidLymphoid enhancer-binding factor 1target
Etacrynic acidGlutathione S-transferase Ptarget
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideHepatic sodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideOrganic anion transporter 3transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideAlbumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideATP-binding cassette sub-family C member 4transporter
HydrochlorothiazideOrganic anion transporter 3transporter
HydrochlorothiazideAngiotensin-converting enzymetarget
TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
TriamtereneAmiloride-sensitive sodium channel subunit betatarget
TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
TriamtereneCytochrome P450 1A2enzyme
PhenazopyridineSodium channel protein type 1 subunit alphatarget
PhenazopyridineGroup A nerve fiberstarget
Lithium carbonateInositol monophosphatase 2target
Lithium carbonateInositol monophosphatase 1target
Lithium carbonateGlycogen synthase kinase-3 betatarget
Lithium carbonateGlutamate receptor 3target
Lithium carbonateAmiloride-sensitive sodium channel subunit alphatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit betatransporter
Lithium carbonateAmiloride-sensitive sodium channel subunit gammatransporter
Lithium citrateInositol monophosphatase 2target
Lithium citrateInositol monophosphatase 1target
Lithium citrateGlycogen synthase kinase-3 betatarget
Lithium citrateGlutamate receptor 3target
GivosiranALAS1 mRNAtarget
Givosiran5-aminolevulinate synthase, non-specific, mitochondrialtarget