Enzyme Precursors

Name
Enzyme Precursors
Accession Number
DBCAT002051
Description

Physiologically inactive substances that can be converted to active enzymes.

Drugs
DrugDrug Description
SaruplaseNot Annotated
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
Factor IX Complex (Human)A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy.
Coagulation factor VII humanA coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia.
Coagulation Factor IX HumanA coagulation factor used to treat hemophilia B or factor IX hemophilia.
PlasminogenPlasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia).
ThrombinA coagulation factor used to stop bleeding during surgery.
ProthrombinA coagulation factor used for emergency reversal of vitamin K antagonist therapy.
Drotrecogin alfaA form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII.
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
Factor XIII (human)A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency.
Coagulation factor X humanA coagulation factor used to treat Factor X deficiency to control bleeding.
Trenonacog alfaHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
Drugs & Drug Targets
DrugTargetType
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
Coagulation factor VII humanTissue factortarget
Coagulation factor VII humanCoagulation factor Xtarget
Coagulation factor VII humanCoagulation factor IXtarget
Coagulation Factor IX HumanCoagulation factor Xtarget
Coagulation Factor IX HumanCoagulation factor XItarget
Coagulation Factor IX HumanCoagulation factor VIItarget
Coagulation Factor IX HumanCoagulation factor VIIItarget
Coagulation Factor IX HumanProthrombintarget
Coagulation Factor IX HumanProlow-density lipoprotein receptor-related protein 1target
Coagulation Factor IX HumanVitamin K-dependent gamma-carboxylasetarget
PlasminogenTissue-type plasminogen activatorenzyme
PlasminogenUrokinase-type plasminogen activatorenzyme
ThrombinProteinase-activated receptor 1target
ThrombinProteinase-activated receptor 4target
ThrombinCoagulation factor XItarget
ThrombinCoagulation factor XIII A chaintarget
ThrombinCoagulation factor XIII B chaintarget
ThrombinFibrinogen alpha chaintarget
ThrombinFibrinogen beta chaintarget
ThrombinFibrinogen gamma chaintarget
ThrombinCoagulation factor Vtarget
ThrombinCoagulation factor VIIItarget
ProthrombinFibrinogen alpha chaintarget
ProthrombinFibrinogen beta chaintarget
ProthrombinCoagulation factor XIII A chaintarget
ProthrombinCarboxypeptidase B2target
ProthrombinCoagulation factor Xenzyme
Drotrecogin alfaCoagulation factor VIIItarget
Drotrecogin alfaCoagulation factor Vtarget
Drotrecogin alfaPlasminogen activator inhibitor 1target
Drotrecogin alfaThrombomodulintarget
Drotrecogin alfaVitamin K-dependent protein Starget
Drotrecogin alfaProthrombintarget
Drotrecogin alfaPlatelet factor 4target
Drotrecogin alfaPlasma serine protease inhibitortarget
Drotrecogin alfaSerpin B6target
Drotrecogin alfaEndothelial protein C receptortarget
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget