- Enzyme Precursors
- Accession Number
Physiologically inactive substances that can be converted to active enzymes.
Drug Drug Description Saruplase Not Annotated Protein C A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. Factor IX Complex (Human) A Factor IX complex used to prevent and treat bleeding episodes in hemophilia B or vitamin K antagonist therapy. Coagulation factor VII human A coagulation factor used to treat bleeding disorders such as hemophilia and Glanzmann's thrombasthenia. Coagulation Factor IX Human A coagulation factor used to treat hemophilia B or factor IX hemophilia. Plasminogen Plasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia). Thrombin A coagulation factor used to stop bleeding during surgery. Prothrombin A coagulation factor used for emergency reversal of vitamin K antagonist therapy. Drotrecogin alfa A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII. Eftrenonacog alfa A recombinant Factor IX used to treat and prevent bleeding in hemophilia B. Factor XIII (human) A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency. Coagulation factor X human A coagulation factor used to treat Factor X deficiency to control bleeding. Trenonacog alfa Human coagulation factor IX (EC 220.127.116.11, Christmas factor, plasma thromboplastin component), produced in CHO cells. Albutrepenonacog alfa A recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B. Nonacog beta pegol A recombinant coagulation Factor IX derivative used to treat hemophilia B.
- Drugs & Drug Targets