Urothelial Cancer (DBCOND0039244)

Identifiers

Synonyms
F. Urothelial Cancer / UC (Urothelial Cancer)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05059522
Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closingtreatment3active_not_recruiting
NCT05489211
Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)treatment2recruiting
NCT06011954
A Study to Survey Adults in South Korea With Cancer Who Receive PADCEV InjectionNot AvailableNot Availablerecruiting
NCT02365597
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancertreatment2active_not_recruiting
NCT03207867
A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphomatreatment2terminated
NCT03390504
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrationstreatment3active_not_recruiting
NCT02379429
Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer TissueNo drug interventionsNot AvailableNot Availablerecruiting
NCT02769962
Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancertreatment1 / 2recruiting
NCT04235777
Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignanciestreatment1recruiting
NCT04923178
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract MalignanciesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05645692
A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancertreatment2recruiting
NCT03096054
A CR-UK Phase I Trial of LY3143921No drug interventionstreatment1active_not_recruiting
NCT04294277
Safety and Efficacy of Pemigatinib in Patients With High-risk Urothelial Cancer After Radical Surgerytreatment2terminated
NCT03288545
A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancertreatment1 / 2active_not_recruiting
NCT02880345
RADVAX™: A Trial of Combined Pembrolizumab and Hypofractionated Radiation in Patients With Advanced Urothelial Cancer Who Have Progressed on Anti-PD-1/PD-L1 Monotherapytreatment1withdrawn
NCT03036098
Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Participants With Untreated Inoperable or Metastatic Urothelial Cancertreatment3active_not_recruiting
NCT04180371
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expressiontreatment1 / 2recruiting
NCT04223856
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancertreatment3active_not_recruiting
NCT01801137
The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urotheliumtreatment2completed
NCT02661100
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patientstreatment1 / 2withdrawn
NCT04044859
ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)No drug interventionstreatment1recruiting
NCT02256436
A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)treatment3completed
NCT03955913
A Study to Identify Participants With Urothelial Cancer and Fibroblast Growth Factor Receptor Gene AberrationsNo drug interventionsNot AvailableNot Availablecompleted
NCT04152018
Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.No drug interventionstreatment1active_not_recruiting
NCT04724018
Sacituzumab Govitecan Plus EV in Metastatic UCtreatment1active_not_recruiting
NCT02516241
Study of MEDI4736 (Durvalumab) With or Without Tremelimumab Versus Standard of Care Chemotherapy in Urothelial Cancertreatment3active_not_recruiting
NCT04131634
Stereotactic Ablative Radiation for Oligo-Progression of Urothelial CancerNo drug interventionstreatment2terminated
NCT02335424
Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-052)treatment2completed
NCT05259696
Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)treatment1 / 2active_not_recruiting
NCT05219435
Study of NIVOLUMAB/IPILIMUMAB Maintenance in Unresectable Locally Advanced or Metastatic Urothelial Cancertreatment2recruiting
NCT01206426
Genetic Determinants of Response to Neoadjuvant Cisplatin-based Chemotherapy in Urothelial CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT00578526
SU011248 for Platinum-Refractory Urothelial Cancer Evaluation Trialtreatment2completed
NCT00821327
Gemzar, Cisp, Sunitinib Urothelial Catreatment2completed
NCT04501094
A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinomatreatment2terminated
NCT03425201
Niraparib in Combination With Cabozantinib (XL184) in Patients With Advanced Urothelial Cancer (NICARAGUA)other1 / 2completed
NCT00872495
Evaluation of Non-Invasive Assays for the Detection of Urothelial CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02111850
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positivetreatment1 / 2completed
NCT00902590
A Genotype-Phenotype Urothelial Cancer RegistryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05279690
Pilot Trial of Colchicine in Urothelial Cancer and Other Solid Tumorstreatment1recruiting
NCT06448364
A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combinationtreatment1active_not_recruiting
NCT03219333
A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancertreatment2completed
NCT05126433
Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors (EMERGE-201)treatment2completed
NCT03983954
Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumorstreatment1active_not_recruiting
NCT02891161
Durvalumab And Radiation Therapy Followed by Adjuvant Durvalumab in Patients With Urothelial Cancer (T2-4 N0-2 M0) of the Bladdertreatment1 / 2unknown_status
NCT02033993
Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen.treatment2completed
NCT02052778
A Study of TAS-120 in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT00995488
Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of Advanced Urothelial Cancertreatment2terminated
NCT03474107
A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)treatment3active_not_recruiting
NCT01663285
Clinical Trial Of Neoadjuvant Chemotherapy (NAC)In Upper Tract Urothelial Carcinoma (UTUC)treatment2terminated
NCT02603432
A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)treatment3completed
NCT04114136
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignanciestreatment2recruiting
NCT05233436
PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumorstreatment1terminated
NCT03317496
Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignanciestreatment1 / 2terminated
NCT04629339
Study of INCB086550 in Select Solid Tumorstreatment2terminated
NCT05366725
A Study to Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After ChemotherapyNot AvailableNot Availablecompleted
NCT02393248
Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)treatment1 / 2terminated
NCT00790426
Phase II Study of TKI258 in Advanced Urothelial Carcinomatreatment2completed
NCT03576131
GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid TumorsNo drug interventionstreatment1 / 2terminated
NCT03472560
A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)treatment2terminated
NCT01700010
Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial Cancertreatment2withdrawn
NCT03406650
Neoadjuvant and Adjuvant Durvalumab in Combination With Neoadjuvant Chemotherapy in Patients With Operable Urothelial Cancer.treatment2active_not_recruiting
NCT03374488
Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial Carcinomatreatment3completed
NCT02178722
Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancerstreatment1 / 2completed
NCT02646748
Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumorstreatment1completed
NCT02872714
A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Urothelial Carcinoma - (FIGHT-201)treatment2completed
NCT02903914
Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumorstreatment1 / 2completed
NCT02298153
A Study of Atezolizumab (MPDL3280A) in Combination With Epacadostat (INCB024360) in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma (ECHO-110)treatment1terminated
NCT02318277
A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)treatment1 / 2completed
NCT03361865
Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)treatment3completed