- Anti-Dyskinesia Agents
- Accession Number
Drugs used in the treatment of movement disorders. Most of these act centrally on dopaminergic or cholinergic systems. Among the most important clinically are those used for the treatment of Parkinson disease (ANTIPARKINSON AGENTS) and those for the tardive dyskinesias.
Drug Drug Description Botulinum toxin type B A purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. Carbidopa A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. Benzatropine An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Ropinirole A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome. Trihexyphenidyl An antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS). Procyclidine An antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms. Pramipexole A non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). Entacapone A selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. Haloperidol An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. Lisuride For the management of Parkinson's Disease Biperiden A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. Progabide Indicated for the treatment of epilepsy. Amantadine A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. Memantine An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. Pimozide An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder. Orphenadrine A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. 3,5-Dinitrocatechol Not Available Opicapone A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor. Deanol Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. Deanol has been used in the treatment... Tolcapone A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Dexetimide A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. Piribedil A dopamine agonist used with or without levodopa in the treatment of Parkinson's disease. Benserazide A medication used to treat Parkinson's disease, parkinsonism, and restless leg syndrome. Melevodopa A methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease. Budipine Not Annotated Dexpramipexole Dexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of...
- Drugs & Drug Targets