Ferrous chloride

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Ferrous chloride is an iron supplement indicated in parenteral nutrition.

Generic Name
Ferrous chloride
DrugBank Accession Number
DB13569
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 126.75
Monoisotopic: 125.872641
Chemical Formula
Cl2Fe
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Alendronic acidFerrous chloride can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium PhosphateFerrous chloride can cause a decrease in the absorption of Calcium Phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium phosphate dihydrateFerrous chloride can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
CarbidopaFerrous chloride can cause a decrease in the absorption of Carbidopa resulting in a reduced serum concentration and potentially a decrease in efficacy.
CinoxacinFerrous chloride can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Ferrous chloride tetrahydrateNot Available13478-10-9WSSMOXHYUFMBLS-UHFFFAOYSA-L
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Nutritrace Concentrate for solution for infusionFerrous chloride tetrahydrate (6.958 mg/10ml) + Chromic chloride hexahydrate (0.053 mg/10ml) + Cupric chloride dihydrate (2.046 mg/10ml) + Manganese chloride tetrahydrate (1.979 mg/10ml) + Potassium Iodide (0.166 mg/10ml) + Sodium selenite pentahydrate (0.0789 mg/10ml) + Sodium fluoride (1.26 mg/10ml) + Sodium molybdate dihydrate (0.0242 mg/10ml) + Zinc chloride (6.815 mg/10ml)SolutionIntravenousB. BRAUN SINGAPORE PTE LTD2013-04-22Not applicableSingapore flag
Tracutil - Konzentrat zur Herstellung einer InfusionslösungFerrous chloride (695.8 mcg/ml) + Chromic chloride (5.3 mcg/ml) + Cupric Chloride (204.6 mcg/ml) + Manganese chloride (197.9 mcg/ml) + Potassium Iodide (16.6 mcg/ml) + Sodium selenite (7.89 mcg/ml) + Sodium fluoride (126 mcg/ml) + Sodium molybdate (2.42 mcg/ml) + Zinc chloride (681.5 mcg/ml)Injection, solution, concentrateIntravenousB. Braun Melsungen Ag2001-02-16Not applicableAustria flag
TRACUTIL® 10 ML AMPOLLASFerrous chloride tetrahydrate (6.958 mg) + Chromic chloride hexahydrate (0.053 mg) + Cupric chloride dihydrate (2.046 mg) + Manganese chloride tetrahydrate (1.979 mg) + Potassium Iodide (0.166 mg) + Sodium selenite pentahydrate (0.0789 mg) + Sodium fluoride (1.26 mg) + Sodium molybdate dihydrate (0.0242 mg) + Zinc chloride (6.815 mg)Solution, concentrateIntravenousB. BRAUN MEDICAL S.A.2006-11-102015-08-10Colombia flag

Categories

ATC Codes
B03AA05 — Ferrous chloride
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as transition metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal salts
Sub Class
Transition metal chlorides
Direct Parent
Transition metal chlorides
Alternative Parents
Inorganic chloride salts
Substituents
Inorganic chloride salt / Inorganic salt / Transition metal chloride
Molecular Framework
Not Available
External Descriptors
iron coordination entity (CHEBI:30812)
Affected organisms
Not Available

Chemical Identifiers

UNII
S3Y25PHP1W
CAS number
7758-94-3
InChI Key
NMCUIPGRVMDVDB-UHFFFAOYSA-L
InChI
InChI=1S/2ClH.Fe/h2*1H;/q;;+2/p-2
IUPAC Name
λ²-iron(2+) ion dichloride
SMILES
[Cl-].[Cl-].[Fe++]

References

General References
  1. BASG: Tracutil (Chromic Chloride, Cupric Chloride, Ferrous Chloride, Manganese, Potassium Iodide, Selenious Acid, Sodium Fluoride, Sodium Molybdate, Zinc Chloride) Intravenous Injection [Link]
ChemSpider
22866
RxNav
24940
ChEBI
30812
ChEMBL
CHEMBL3183704
Wikipedia
Iron(II)_chloride

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravenous0.053 mg/10ml
Injection, solution, concentrateIntravenous
Solution, concentrateIntravenous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility33.1 mg/mLALOGPS
logP0.98ALOGPS
logP0.61Chemaxon
logS-0.58ALOGPS
pKa (Strongest Acidic)-7Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity5.62 m3·mol-1Chemaxon
Polarizability2.39 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 23, 2017 20:44 / Updated at May 29, 2021 18:11